Results 21 to 30 of about 577,014 (316)
Cancer cell survival depends on collagen uptake into tumor-associated stroma
Nature Communications, 2022 Collagen can be a metabolic source to fuel cancer growth. Here the authors show that cell surface protein TEM8 mediates the binding and uptake of collagen in stromal cells and these cells processed the collagen to glutamine, providing an alternative ...
Kuo-Sheng Hsu +21 more
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VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone
npj Regenerative Medicine, 2023 Vascular endothelial growth factor-A (VEGF) physiologically regulates both angiogenesis and osteogenesis, but its application in bone tissue engineering led to contradictory outcomes.
Andrea Grosso +8 more
doaj +1 more source
STAR Protocols, 2021 Summary: Tumor-associated macrophages (TAMs) are highly heterogenous regarding their intratumoral localization, surface marker expression, and molecular properties.
Pawel Bieniasz-Krzywiec +3 more
doaj +1 more source
Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]
, 2005 Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
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The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer [PDF]
, 2005 <b>OBJECTIVE</b>: To test the hypothesis that angiogenesis in prostate cancer is associated with tumour invasion and metastasis, and that this is mediated through increased cyclooxygenase-2 (COX-2) expression.
Mukherjee, R. +3 more
core +1 more source
High mitogenic stimulation arrests angiogenesis
Nature Communications, 2019 High mitogenic stimuli have been suggested to promote endothelial cell proliferation and sprouting during angiogenesis. Here Pontes-Quero et al., by interfering with levels of VEGF and Notch signalling in single endothelial cells in vivo, find that high ...
Samuel Pontes-Quero +9 more
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Publisher Correction: High mitogenic stimulation arrests angiogenesis
Nature Communications, 2019 The original version of this Article contained errors in Fig. 8. In panel a, the labels ‘VEGF’, ‘Notch’, ‘p21’, and ‘P-ERK’ were inadvertently omitted. This has been corrected in the PDF and HTML versions of the Article.
Samuel Pontes-Quero +9 more
doaj +1 more source
How Endothelial Cells Adapt Their Metabolism to Form Vessels in Tumors
Frontiers in Immunology, 2017 Endothelial cells (ECs) line blood vessels, i.e., vital conduits for oxygen and nutrient delivery to distant tissues. While mostly present as quiescent “phalanx” cells throughout adult life, ECs can rapidly switch to a migratory “tip” cell and a ...
Annalisa Zecchin +7 more
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VEGF family members : modulators of tumor angiogenesis and lymphangiogenesis [PDF]
, 2006 Members of the vascular endothelial growth factor (VEGF) family and their receptors (VEGFR) play an essential role in the development and maintenance of the blood and lymphatic vasculature.
Kopfstein, Lucie
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Glycolytic regulation of cell rearrangement in angiogenesis
Nature Communications, 2016 Glycolytic regulator PFKFB3 is a key player in vessel sprouting. Here the authors develop a computational model predicting that PFKFB3 drives endothelial cell rearrangement during vessel sprouting by promoting filopodia formation and reducing ...
Bert Cruys +15 more
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