The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer [PDF]
, 2005 <b>OBJECTIVE</b>: To test the hypothesis that angiogenesis in prostate cancer is associated with tumour invasion and metastasis, and that this is mediated through increased cyclooxygenase-2 (COX-2) expression.
Mukherjee, R. +3 more
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VEGF family members : modulators of tumor angiogenesis and lymphangiogenesis [PDF]
, 2006 Members of the vascular endothelial growth factor (VEGF) family and their receptors (VEGFR) play an essential role in the development and maintenance of the blood and lymphatic vasculature.
Kopfstein, Lucie
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Glycolytic regulation of cell rearrangement in angiogenesis
Nature Communications, 2016 Glycolytic regulator PFKFB3 is a key player in vessel sprouting. Here the authors develop a computational model predicting that PFKFB3 drives endothelial cell rearrangement during vessel sprouting by promoting filopodia formation and reducing ...
Bert Cruys +15 more
doaj +1 more source
Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]
, 2007 This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
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Poststroke Angiogenesis, Con [PDF]
Stroke, 2015 Angiogenesis, the regrowth of new blood vessels, occurs after stroke1 and thus raises hopes that this regeneration is beneficial for patients with stroke. There is no doubt, that the restoration of blood supply, providing oxygen and nutrients to the ischemic brain tissue, is beneficial for stroke recovery.
J. Adamczak, M. Hoehn
openaire +3 more sources
iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
Nature Communications, 2019 The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre ...
Macarena Fernández-Chacón +6 more
doaj +1 more source
Quantitative assessment of angiogenesis in murine antigen-induced arthritis by intravital fluorescence microscopy [PDF]
, 2003 Inhibition of angiogenesis might be a therapeutic approach to prevent joint destruction caused by the overgrowing synovial tissue during chronic joint inflammation.
Schmitt-Sody, M. +7 more
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EGFL7 meets miRNA-126 : an angiogenesis alliance [PDF]
, 2010 Blood vessels form de novo through the tightly regulated programs of vasculogenesis and angiogenesis. Both processes are distinct but one of the steps they share is the formation of a central lumen, when groups of cells organized as vascular cords ...
Plate, Karl +5 more
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Highly tunable delivery of matrix-bound growth factors for therapeutic angiogenesis [PDF]
, 2014 Therapeutic angiogenesis is a promising strategy to treat pathologies characterized by insufficient blood supply to tissue, such as coronary and peripheral artery diseases, but also to promote the engraftment and survival of tissue-engineered constructs ...
Sacchi, Veronica
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Prioritization and functional validation of target genes from single-cell transcriptomics studies
Communications Biology, 2023 Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional validation, it
Liliana Sokol +12 more
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