Results 31 to 40 of about 577,014 (316)

Quantitative assessment of angiogenesis in murine antigen-induced arthritis by intravital fluorescence microscopy [PDF]

, 2003
Inhibition of angiogenesis might be a therapeutic approach to prevent joint destruction caused by the overgrowing synovial tissue during chronic joint inflammation.
Schmitt-Sody, M., Zysk, S. P., Pellengahr, C., Refior, H. J., Messmer, K., Krombach, F., Landes, J., Veihelmann, A.   +7 more
core   +1 more source

Poststroke Angiogenesis, Con [PDF]

Stroke, 2015
Angiogenesis, the regrowth of new blood vessels, occurs after stroke1 and thus raises hopes that this regeneration is beneficial for patients with stroke. There is no doubt, that the restoration of blood supply, providing oxygen and nutrients to the ischemic brain tissue, is beneficial for stroke recovery.
J. Adamczak, M. Hoehn
openaire   +3 more sources

iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

Nature Communications, 2019
The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre ...
Macarena Fernández-Chacón, Verónica Casquero-García, Wen Luo, Federica Francesca Lunella, Susana Ferreira Rocha, Sergio Del Olmo-Cabrera, Rui Benedito   +6 more
doaj   +1 more source

Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]

, 2007
This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
core   +1 more source

Angiogenesis in Melanoma [PDF]

Seminars in Oncology, 2007
The process of angiogenesis is crucial for progression and metastasis of the majority of solid tumors including melanomas. The current review summarizes existing knowledge of the mechanisms of angiogenesis in melanoma, as well as current anti-angiogenic therapeutic strategies and their targets.
Ganapati H, Mahabeleshwar, Tatiana V, Byzova   +1 more
openaire   +2 more sources

Angiogenesis in tissue engineering : Breathing life into constructed tissue substitutes [PDF]

, 2006
Long-term function of three-dimensional (3D) tissue constructs depends on adequate vascularization after implantation. Accordingly, research in tissue engineering has focused on the analysis of angiogenesis.
Germann, Gunter, Rücker, Martin, Haeufel, Joerg M., Torio-Padron, Nestor, Ruecker, Martin, Carvalho, Carlos, Heberer, Michael, Junker, Dominic, Häufel, Jörg M., Ring, Andrej, Amon, Michaela, Farhadi, Jian, Menger, Michael D., Vollmar, Brigitte, Laschke, Matthias W., Martin, Ivan, Harder, Yves, Schramm, Rene   +17 more
core   +1 more source

Highly tunable delivery of matrix-bound growth factors for therapeutic angiogenesis [PDF]

, 2014
Therapeutic angiogenesis is a promising strategy to treat pathologies characterized by insufficient blood supply to tissue, such as coronary and peripheral artery diseases, but also to promote the engraftment and survival of tissue-engineered constructs ...
Sacchi, Veronica
core   +1 more source

Angiogenesis in implantation [PDF]

Journal of Assisted Reproduction and Genetics, 2007
Implantation failure and early pregnancy loss are common following natural conceptions and they are particularly important clinical hurdles to overcome following assisted reproduction attempts. The importance of adequate vascular development and maintenance during implantation has recently become a major focus of investigation.Review of current ...
Donald S, Torry, Jonathan, Leavenworth, Miao, Chang, Vatsala, Maheshwari, Kathleen, Groesch, Evan R, Ball, Ronald J, Torry   +6 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling

, 2013
The contribution of blood flow to angiogenesis is incompletely understood. We examined the effect of blood flow on Notch signalling in the vasculature of zebrafish embryos, and whether blood flow regulates angiogenesis in zebrafish with constitutively up-
McMahon, Kathryn, Rothman, A.M.K., Gray, Caroline, Haase, A., Haase, Andrea, Novodvorsky, P., Rothman, Alexander M K, Van Eeden, Fredericus J. M., Gering, Martin, Crossman, D.C., Chico, Timothy J. A., Watson, O., Crossman, David C, Chico, Timothy J A, Gering, M., Rothman, Alexander M. K., Crossman, David C., Novodvorsky, Peter, Lawrie, A., McMahon, K., Van Eeden, Fredericus J M, Lawrie, Allan, Van Eeden, F.J.M., Chico, T.J.A., Watson, Oliver, Gray, C.   +25 more
core   +1 more source