Results 31 to 40 of about 618,864 (305)
Angiogenesis in tissue engineering : Breathing life into constructed tissue substitutes [PDF]
, 2006 Long-term function of three-dimensional (3D) tissue constructs depends on adequate vascularization after implantation. Accordingly, research in tissue engineering has focused on the analysis of angiogenesis.
Germann, Gunter +17 more
core +1 more source
Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities
EMBO Molecular Medicine, 2016 Cancer cell metabolism has received increasing attention. Despite a boost in the application of clinical metabolic profiling (CMP) in cancer patients, a meta‐analysis has not been performed.
Jermaine Goveia +9 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background The present study demonstrates that the ubiquitin E3 ligase, Pellino‐1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk‐1.
Mahesh Thirunavukkarasu +13 more
doaj +1 more source
Cell Death and Disease, 2021 Dental pulp stem cells (DPSC) are capable of differentiating into vascular endothelial cells. Although the capacity of vascular endothelial growth factor (VEGF) to induce endothelial differentiation of stem cells is well established, mechanisms that ...
Zhaocheng Zhang +3 more
doaj +1 more source
Angiogenesis and angiogenesis inhibitors in paediatric diseases
European Journal of Pediatrics, 1992 Angiogenesis, the generation of new capillaries from existing blood vessels, is rarely observed in the healthy organism, but can present during various paediatric diseases. In this review, we describe recent progress in the understanding of pathological angiogenesis and approaches for an improved therapy of angiogenic childhood diseases.
Schweigerer, L., Fotsis, T.
openaire +3 more sources
Angiogenesis and schistosomiasis [PDF]
Memórias do Instituto Oswaldo Cruz, 2010 Angiogenesis has been recognised as a precursor of fibrosis in several pathologic conditions. Its participation has been demonstrated in schistosomiasis, both during periovular granuloma formation and in the genesis of schistosomal periportal fibrosis. Paradoxically, proliferation of new blood vessels, accompanied by production of vascular-endothelial ...
Andrade, Zilton A. +1 more
openaire +4 more sources
A transgenic Xenopus laevis reporter model to study lymphangiogenesis
Biology Open, 2013 Summary The importance of the blood- and lymph vessels in the transport of essential fluids, gases, macromolecules and cells in vertebrates warrants optimal insight into the regulatory mechanisms underlying their development.
Annelii Ny +13 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
PHD2 regulates arteriogenic macrophages through TIE2 signalling
EMBO Molecular Medicine, 2013 Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previously reported that macrophages genetically modified to express low levels of prolyl hydroxylase domain protein 2 (PHD2) display an arteriogenic phenotype ...
Alexander Hamm +14 more
doaj +1 more source
Angiogenesis, 2010 Imaging of angiogenesis is an important tool in the diagnosis of disease. Small molecule or nanoparticular probes are currently developed to identify angiogenic endothelium with non-invasive imaging techniques such as magnetic resonance and ultrasound imaging. These techniques are very valuable since they would not only contribute to improved diagnosis,
Mulder, Willem J. M. +1 more
openaire +3 more sources