Results 11 to 20 of about 209,193 (336)
Current Oncology, 2021 Solid organ transplant recipients on long-term immunosuppressive medication are at increased risk of developing malignancy, and treatment of advanced cancers with angiogenesis inhibitors in this context has not been widely studied.
Lawrence Kasherman +6 more
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Thalidomide is an inhibitor of angiogenesis. [PDF]
Proceedings of the National Academy of Sciences, 1994 Thalidomide is a potent teratogen causing dysmelia (stunted limb growth) in humans. We have demonstrated that orally administered thalidomide is an inhibitor of angiogenesis induced by basic fibroblast growth factor in a rabbit cornea micropocket assay.
Michael S. Loughnan +3 more
openaire +4 more sources
Cardiotoxic effects of angiogenesis inhibitors [PDF]
Clinical Science, 2021 Abstract The development of new therapies for cancer has led to dramatic improvements in survivorship. Angiogenesis inhibitors represent one such advancement, revolutionising treatment for a wide range of malignancies. However, these drugs are associated with cardiovascular toxicities which can impact optimal cancer treatment in the ...
Dobbin, Stephen J.H. +4 more
openaire +4 more sources
Frontiers in Pharmacology, 2023 Currently, for ovarian cancer, which has the highest mortality rate among all gynecological cancers, the standard treatment protocol is initial tumor cytoreductive surgery followed by platinum-based combination chemotherapy.
Xu Huang +7 more
doaj +1 more source
Angiogenesis Inhibitors in NSCLC [PDF]
International Journal of Molecular Sciences, 2017 Angiogenesis is a complex biological process that plays a relevant role in sustaining the microenvironment, growth, and metastatic potential of several tumors, including non-small cell lung cancer (NSCLC). Bevacizumab was the first angiogenesis inhibitor approved for the treatment of patients with advanced NSCLC in combination with chemotherapy ...
Nicola Normanno +10 more
openaire +3 more sources
Body Composition to Define Prognosis of Cancers Treated by Anti-Angiogenic Drugs
Diagnostics, 2023 Background: Body composition could help to better define the prognosis of cancers treated with anti-angiogenics. The aim of this study is to evaluate the prognostic value of 3D and 2D anthropometric parameters in patients given anti-angiogenic treatments.
Pierre Decazes +10 more
doaj +1 more source
On-Target Side Effects of Targeted Therapeutics of Cancer
Pathology and Oncology Research, 2022 The concept of precision medicine is based on the identification of hallmarks of cancer to exploit them as drug targets. The basic idea was that in this way the therapeutic modalities will be more effective and the side effects will be less.
József Tímár, Andrea Uhlyarik
doaj +1 more source
Российский офтальмологический журнал, 2023 Purpose: data analysis of Russia’s first register of neovascular age-related macular degeneration (nAMD) — a web-based system for clinical monitoring of nAMD patients designed to collect and accumulate the data on such patients, their demographic, social
V. V. Neroev +4 more
doaj +1 more source
Computational modelling of angiogenesis: The importance of cell rearrangements during vascular growth [PDF]
WIREs Mechanisms of Disease, e1634 (2023), 2023 Angiogenesis is the process wherein endothelial cells (ECs) form sprouts that elongate from the pre-existing vasculature to create new vascular networks. In addition to its essential role in normal development, angiogenesis plays a vital role in pathologies such as cancer, diabetes and atherosclerosis.
arxiv +1 more source
Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use
Case Reports in Dentistry, 2020 Objective. An angiogenesis inhibitor can cause medication-related osteonecrosis of the jaw (MRONJ). To our knowledge, there has been no report that an angiogenesis inhibitor causes delayed healing of tooth extraction socket.
Yosuke Iijima +5 more
doaj +1 more source