Results 41 to 50 of about 373,608 (350)

Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid

open access: yeseLife, 2021
Disorders of the transparent cornea affect millions of people worldwide. However, how to maintain and/or regenerate this organ remains unclear. Here, we show that Rela (encoding a canonical NF-κB subunit) ablation in K14+ corneal epithelial stem cells ...
Qian Yu   +5 more
doaj   +1 more source

PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]

open access: yes, 2019
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit   +7 more
core   +1 more source

Homeobox genes in normal and abnormal vasculogenesis [PDF]

open access: yes, 2008
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M   +3 more
core   +1 more source

Endogenous inhibitors of angiogenesis [PDF]

open access: yesJournal of Cell Science, 2001
In the course of embryonic development, during some normal physiological processes in the adult, such as the female reproductive cycle, and also in a variety of pathologies, including tumour growth, new blood vessels develop from the pre-existing vascular network through endothelial cell sprouting,
openaire   +3 more sources

Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two

open access: yesOftalʹmologiâ, 2014
Purpose: To evaluate of retinal morphology and function progress in patients with diabetes type 2 and DME consistent with the level of pathogenetic factor in tear fluid.Methods: The progress of visual acuity, retinal thickness and photosensitivity after ...
L. K. Moshetova   +5 more
doaj   +3 more sources

Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis [PDF]

open access: yes, 2016
This is the preprint version of our manuscript, corresponding to the article that has been 
published in final form at FOOD CHEMISTRY with DOI: 10.1016/j.foodchem.2016.10.111The health benefits of olive oil are attributed to their bioactive compounds ...
García-Vilas, Javier A.   +2 more
core   +1 more source

A case of vascularized corneal opacity treated with aflibercept

open access: yesJournal of Ophthalmology, 2020
Background: Corneal neovascularization (CNV) is a serious condition that can lead to a profound decline in vision. Current research on treating CNV with angiogenesis inhibitors is underway in numerous centers, and a number of studies have demonstrated ...
A.S. Cholak   +4 more
doaj   +1 more source

Angelica Dahurica ethanolic extract improves impaired wound healing by activating angiogenesis in diabetes. [PDF]

open access: yesPLoS ONE, 2017
Abnormal angiogenesis plays an important role in impaired wound healing and development of chronic wounds in diabetes mellitus. Angelica dahurica radix is a common traditional Chinese medicine with wide spectrum medicinal effects.
Xiao-Na Zhang   +6 more
doaj   +1 more source

Efficacy and safety of low‐dose apatinib in ovarian cancer patients with platinum‐resistance or platinum‐refractoriness: A single‐center retrospective study

open access: yesCancer Medicine, 2020
Background This study aimed to evaluate the efficacy and safety of apatinib with a low dose of 250 mg/d in the treatment of platinum‐resistant or platinum‐refractory ovarian cancer patients. Methods Patients with platinum‐resistant or platinum‐refractory
Wei Chen   +3 more
doaj   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

open access: yes, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

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