Results 31 to 40 of about 323,752 (284)

High endothelial venules predict response to PD-1 inhibitors combined with anti-angiogenesis therapy in NSCLC

Scientific Reports, 2023
Tumor-associated high endothelial venules (TA-HEVs) mediate lymphocyte entry into tumors. Therefore, combined anti-angiogenesis therapy and programmed death-1 (PD-1) inhibitors might stimulate tumor immunity.
Dafu Ye, Yao Jin, Yiming Weng, Xue Cui, Jinsong Wang, Min Peng, Qibin Song   +6 more
doaj   +1 more source

The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells [PDF]

, 2016
The angiogenic inducer CCN1 (Cysteine-rich 61, CYR61) is differentially activated in metastatic breast carcinomas. However, little is known about the precise mechanisms that underlie the pro-metastatic actions of CCN1. Here, we investigated the impact of
Espinoza, Ingrid, Lupu, Ruth, Menendez, Javier A., Vellón, Luciano   +3 more
core   +1 more source

Anti-angiogenesis in prostate cancer: knocked down but not out

Asian Journal of Andrology, 2014
Angiogenesis is a very complex physiological process, which involves multiple pathways that are dependent on the homeostatic balance between the growth factors (stimulators and inhibitors).
Marijo Bilusic, Yu-Ning Wong
doaj   +1 more source

MTOR cross-talk in cancer and potential for combination therapy [PDF]

, 2018
The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions.
Bazzichetto, C., Bria, E., Ciuffreda, L., Cognetti, F., Conciatori, F., Falcone, I., Milella, M, Pilotto, S.   +7 more
core   +3 more sources

Endogenous Matrix-Derived Inhibitors of Angiogenesis

Pharmaceuticals, 2010
Endogenous inhibitors of angiogenesis are proteins or fragments of proteins that are formed in the body, which can inhibit the angiogenic process. These molecules can be found both in the circulation and sequestered in the extracellular matrix (ECM ...
Hans Petter Eikesdal, Malin Sund, Pia Nyberg   +2 more
doaj   +1 more source

The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer [PDF]

, 2005
<b>OBJECTIVE</b>: To test the hypothesis that angiogenesis in prostate cancer is associated with tumour invasion and metastasis, and that this is mediated through increased cyclooxygenase-2 (COX-2) expression.
Bartlett, J.M.S., Edwards, J., Mukherjee, R., Underwood, M.A.   +3 more
core   +1 more source

The Role of a Single Angiogenesis Inhibitor in the Treatment of Recurrent Glioblastoma Multiforme: A Meta-Analysis and Systematic Review.

PLoS ONE, 2016
BackgroundCurrently, the standard treatment for newly diagnosed glioblastoma multiforme (GBM) is maximal safe surgical resection followed by radiation therapy with concurrent and adjuvant temozolomide.
Yawei Wang, Dan Xing, Meng Zhao, Jie Wang, Yang Yang   +4 more
doaj   +1 more source

Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis [PDF]

, 2016
This is the preprint version of our manuscript, corresponding to the article that has been 
published in final form at FOOD CHEMISTRY with DOI: 10.1016/j.foodchem.2016.10.111The health benefits of olive oil are attributed to their bioactive compounds ...
García-Vilas, Javier A., Medina, Miguel Ángel, Quesada, Ana R.   +2 more
core   +1 more source

Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors [PDF]

, 2015
Over the past few years, knowledge regarding the molecular pathology of sporadic pancreatic neuroendocrine tumors (PNETs) has increased substantially, and a number of targeted agents have been tested in clinical trials in this tumor type.
Ahn, Balogh, Bergers, Berruti, Capurso, Capurso, Carew, Castellano, Chamberlain, Chan, Chan, Chen, Clynes, Corbo, Corbo, Couvelard, De Wilde, Di Florio, Di Florio, Di Florio, Fazio, Fendrich, Gaur, Gurung, Han, Heaphy, Heaphy, Hobday, Hopfner, House, Jacinto, Jensen, Jiao, Karnik, Karnik, Komori, Kulke, Laplante, Loewith, Lovejoy, Luzi, Marinoni, Marion-Audibert, Mendel, Meric-Bernstam, Missiaglia, Mocellin, Panzuto, Papouchado, Passacantilli, Perren, Pàez-Ribes, Raymond, Sarbassov, Scoazec, Shah, Shi, Tang, Vinagre, Wang, Yang, Yao, Yuan, Zhang, Zhang   +64 more
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Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz, Ahmadzadeh, Al-Zhoughbi, Albina, Alkan, Allard, Allen, Altman, Alves-Filho, Amelio, Araújo, Argilés, Arora, Arts, Aslanian, Astaldi, Attieh, Augsten, Auvinen, Babbar, Baker, Balasubramanian, Baltazar, Bauer, Bello-Fernandez, Beloribi-Djefaflia, Berchner-Pfannschmidt, Berge, Berrone, Birendra, Bloch-Frankenthal, Bock, Bock, Bonuccelli, Boros, Boudreau, Boukalova, Britten, Brooks, Broome, Bueno, Buqué, Burnet, Cadamuro, Cahlin, Cantelmo, Cao, Carito, Carmeliet, Carmeliet, Caro, Carrascosa, Casazza, Caspani, Catane, Cavalcante, Chakravarty, Chakravarty, Chakravarty, Chang, Chang, Chang, Chappell, Chaudhary, Chen, Chen, Chen, Chiarini, Chittezhath, Choi, Choi, Clark, Clem, Clem, Cohen, Colegio, Collins, Commisso, Covarrubias, Covarrubias, Dang, Dang, Das, Dasgupta, Daurkin, DeBerardinis, DeBerardinis, Delgoffe, Delgoffe, Dell’ Antone, Desai, DiNapoli, Dirat, Dobrina, Doherty, Dong, Draoui, Dufour, Eason, Eelen, El Sayed, Elia, Elwood, Eminel, Fallarino, Farabegoli, Farber, Feun, Fields, Figueras, Filipp, Fischer, Flaig, Flint, Floor, Floridi, Folkman, Folkman, Franklin, Gacche, Ganeshan, Garber, García-Caballero, García-Faroldi, García-Faroldi, Gatenby, Gazi, Geiger, Gentric, Gerner, Gershtein, Ghashghaeinia, Gonen, Goveia, Granchi, Grieninger, Grivennikov, Gross, Gunnink, Guo, Guo, Guppy, Guth, Halestrap, Han, Hanahan, Hanahan, Hanai, Harjes, Harjes, Haskell, Hatzivassiliou, Hayakawa, Hessini, Hitosugi, Ho, Ho, Hoff, Holm, Hosono, Huang, Hubler, Hui, Häusler, Hée, Ignatenko, Ioannesyants, Ip, Jiménez-Valerio, Jiménez-Valerio, Jochems, Johansen, Jones, Kabat, Kafkewitz, Kamphorst, Kamphorst, Kamphorst, Kannan, Karpel-Massler, Katt, Kawasaki, Kelly, Kim, Klimp, Ko, Koliaraki, Kouidhi, Koukourakis, Kridel, Krishna, Kroemer, Krützfeldt, Kubatka, Kucharzewska, la Cueva, Labow, Laing, Lampropoulou, Le, Lechowski, Lee, Lee, Leek, Leighton, Leopold, LePage, Lerma Barbaro, Li, Lin, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Lopes-Coelho, Lu, Lucca, Lukey, Lunt, Luo, López-Lázaro, Löb, Ma, Madaan, Maity, Marchiq, Martinez-Outschoorn, Martinez-Outschoorn, Maráz, Mashima, Masri, Matusewicz, McCann, McKee, McLaughlin, Medina, Medina, Merchan, Meyer, Mider, Missiaen, Mitra, Mockler, Moreno-Sánchez, Morrison, Mu, Murray-Stewart, Márquez, Márquez, Nacev, Nancolas, Newsholme, Nieman, Nisoli, Noman, Norrby, Noy, Nurjhan, Nyberg, Ocaña, Ohmura, Oka, Opitz, Orimo, Pallangyo, Palm, Panda, Papandreou, Parra-Bonilla, Parry, Pascual, Pasquier, Patsoukis, Pavlides, Pavlova, Pelicano, Pellerin, Pennisi, Penny, Peters, Pisarsky, Pizer, Polanski, Polet, Pollard, Polyak, Possemato, Potente, Potente, Prager, Prager, Pushkina, Pérez-Escuredo, Quatromoni, Quesada, Quesada, Rabold, Ramjiawan, Rashid, Rattigan, Reihill, Reitzer, Ribatti, Ribatti, Ribeiro, Richard, Rider, Roberts, Rodríguez-González, Rodríguez-Prados, Rohle, Romero, Romero-García, Roy, Roy, Ruan, Ruiz-Pérez, Russell, Ryu, Saez, Salimian Rizi, Salimian Rizi, Samal, Samudio, Santos, Sanuphan, Sasaki, Saulnier Sholler, Scherz-Shouval, Schoors, Schulze, Segura, Sekar, Selak, Seltzer, Serafini, Shapot, Shapot, Shapot, Sharkia, Shime, Shin, Shurbaji, Sieber, Siu, Skelton, Song, Sonveaux, Sonveaux, Souba, Sousa, Spahr, Spinelli, Spolarics, Stacpoole, Stern, Stuart, Stumvoll, Su, Sukumar, Sánchez-López, Tachibana, Takigawa, Talekar, Tanese, Tang, Tannahill, Tebbe, Thomas, Thomas, Thornburg, Tisdale, Torosian, Torres, Trudeau, Ullah, Uray, Urdiales, Vander Heiden, Vander Heiden, Varricchi, Vasudevan, Velaei, Vera, Vornovitskaya, Végran, Wagner, Wakil, Wang, Wang, Wang, Wang, Warburg, Warburg, Wen, Whitaker-Menezes, Williams-Ashman, Wilson, Wood, Woodward, Woster, Wu, Wu, Xie, Yamanishi, Yang, Yang, Yau, Yen, Yoshida, Yoshizaki, Yu, Yuan, Yuan, Yuan, Yun, Zabala-Letona, Zahalka, Zhan, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zhou, Zhu, Ziegler   +431 more
core   +2 more sources