Results 11 to 20 of about 215,305 (295)
Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors. [PDF]
PLoS ONE, 2013 Current inhibitors of angiogenesis comprise either therapeutic antibodies (e.g. bevacicumab binding to VEGF-A) or small molecular inhibitors of receptor tyrosin kinases like e.g. sunitinib, which inhibits PDGFR and VEGFR.
Sabine B Weitensteiner +8 more
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Endogenous inhibitors of angiogenesis [PDF]
Journal of Cell Science, 2001 In the course of embryonic development, during some normal physiological processes in the adult, such as the female reproductive cycle, and also in a variety of pathologies, including tumour growth, new blood vessels develop from the pre-existing vascular network through endothelial cell sprouting,
Ruhrberg, C
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Endogenous Matrix-Derived Inhibitors of Angiogenesis [PDF]
Pharmaceuticals, 2010 Endogenous inhibitors of angiogenesis are proteins or fragments of proteins that are formed in the body, which can inhibit the angiogenic process. These molecules can be found both in the circulation and sequestered in the extracellular matrix (ECM ...
Hans Petter Eikesdal +2 more
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Angiogenesis: Antiangiogenesis Strategy and Angiogenesis Inhibitors [PDF]
, 2010 Angiogenesis is the development of new blood vessels from preexisting vasculature. The angiogenic process is controlled by the net balance between molecules with positive and negative regulatory activity. In the past three decades, the understanding of the fundamental role of angiogenesis in tumor growth, progression and metastasis has led to ...
null Theodora Kerenidi +1 more
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Marine-Derived Angiogenesis Inhibitors for Cancer Therapy [PDF]
Marine Drugs, 2013 Angiogenesis inhibitors have been successfully used for cancer therapy in the clinic. Many marine-derived natural products and their analogues have been reported to show antiangiogenic activities.
Ying-Qing Wang, Ze-Hong Miao
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Angiogenesis: signaling pathways and their inhibitors [PDF]
Медицинская иммунология, 2019 Angiogenesis refers to the formation of new blood vessels from existing ones and is considered a crucial stage in vascular development. Two distinct types of angiogenesis have been identified: branching and non-branching angiogenesis.
Ksenia L. Markova +4 more
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Zhongliu Fangzhi Yanjiu, 2021 Advanced triple-negative breast cancer(TNBC) has less treatments, shorter survival time and poorer prognosis than other subtypes of breast cancer. The rapid development of immunotherapy in recent years is expected to prolong the survival time of advanced
HUANG Shifen, LING Xiaoling
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Oftalʹmologiâ, 2014 Purpose: To evaluate the potential of endostatin, tumstatin and PEDF in avasculargenic therapy.Methods: The avasculargenic potential of the natural angiogenesis inhibitors was explored on the model of alkaline burn, attended with angiogenesis of cornea ...
V. G. Likhvantseva +8 more
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Pharmaceuticals, 2010 Angiogenesis is regulated by the local balance between angiogenesis stimulators and inhibitors. A number of endogenous angiogenesis inhibitors have been found in the body. The origin of these inhibitors is mostly extrinsic to the vasculature.
Yasufumi Sato
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IJU Case Reports, 2020 Introduction Nivolumab is effective for advanced renal cell carcinoma; however, reports are limited wherein nivolumab is combined with sequential therapy of angiogenesis inhibitors and metastasectomy.
Hiroki Hagimoto +8 more
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