Results 91 to 100 of about 9,670 (235)

A practical approach to panel design, validation, and interpretation for the evaluation of T‐cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, Volume 108, Issue 6, Page 430-447, November 2025.
Abstract The diagnosis of T‐cell neoplasms remains one of the most challenging areas in hematopathology due to the immunophenotypic heterogeneity and subtle aberrancies often present in these entities. This “Best Practice” manuscript provides a practical framework for laboratories to design, validate, and interpret immunophenotyping studies of immature
Jean Oak, Felipe Magalhaes Furtado, Katherine A. Devitt, Pedro Horna, Jonathan R. Fromm, Lianqun Qiu, Andrea Illingworth, Jolene Cardinali, Wolfgang Kern, Ahmad Al‐Attar, Min Shi   +10 more
wiley   +1 more source

Primary nodal peripheral T-cell lymphomas: diagnosis and therapeutic considerations

Revista Brasileira de Hematologia e Hemoterapia, 2015
Nodal peripheral T-cell lymphomas are a rare group of neoplasms derived from post-thymic and activated T lymphocytes. A review of scientific articles listed in PubMed, Lilacs, and the Cochrane Library databases was performed using the term "peripheral T ...
Luis Alberto de Pádua Covas Lage, Tamara Carvalho dos Santos Cabral, Renata de Oliveira Costa, Marianne de Castro Gonçalves, Debora Levy, Maria Cláudia Nogueira Zerbini, Juliana Pereira   +6 more
doaj   +1 more source

Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine

Frontiers in Oncology, 2020
Peripheral T-cell lymphoma (PTCL) is a rare, heterogenous group of mature T-cell neoplasms that comprise 10–15% of non-Hodgkin lymphoma cases in the United States. All subtypes of PTCL, except for ALK+ anaplastic T-cell lymphoma, are associated with poor
Yumeng Zhang, Dasom Lee, Thomas Brimer, Mohammad Hussaini, Lubomir Sokol   +4 more
doaj   +1 more source

Randomized Phase II Study of Brentuximab‐Vedotin With High‐Dose Chemotherapy in CD30 Positive Lymphoma

Hematological Oncology, Volume 43, Issue 6, November 2025.
ABSTRACT Patients with Hodgkin lymphoma (HL) or peripheral T‐cell lymphoma (PTCL) who relapse after high‐dose chemotherapy (HDCT) have a dismal prognosis. Brentuximab‐vedotin (BV) is a CD30‐targeting antibody‐drug‐conjugate (ADC) used in first‐line‐, salvage‐, and maintenance‐therapy of HL, as well as first‐line‐ and salvage‐therapy of PTCL. In phase I
Christian Rausch, Ulrike Bacher, Manuela Rabaglio, Corinne Vorburger, Anke Klingenberg, Yara Banz, Michael Daskalakis, Thomas Pabst   +7 more
wiley   +1 more source

Angioimmunoblastic T-cell Lymphoma: A Case Report

Pakistan Journal of Medicine and Dentistry
Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive type of non-Hodgkin's lymphoma (NHL) that is mostly diagnosed in elderly patients. Its non-specific clinical presentation (lymphadenopathy, fever, night sweats, weight loss, generalized ...
Sundus Nasim, Dua Azim, Farheen Malik, Faryal Tahir, Zehra Ashraf, Abdul Qayyum   +5 more
doaj   +1 more source

Prognostic Significance of TBX21 and GATA3 Subtype Classification in Indolent Adult T‐Cell Leukemia‐Lymphoma With Cutaneous Lesions

The Journal of Dermatology, Volume 52, Issue 11, Page 1674-1681, November 2025.
ABSTRACT Chronic‐type adult T‐cell leukemia‐lymphoma (ATL) without unfavorable prognostic factors and smoldering‐type ATL are classified as indolent ATL. Indolent ATL patients often present with cutaneous lesions, but their clinical course is diverse. Smoldering‐type ATL presenting with tumoral cutaneous lesions and without lung involvement has a poor ...
Kazuhiro Kawai, Youhei Uchida, Takuro Kanekura   +2 more
wiley   +1 more source

Effect of Valemetostat on the Pharmacokinetics of Midazolam and Digoxin: A Phase 1 Drug–Drug Interaction Study in Patients With Non‐Hodgkin Lymphoma

Clinical and Translational Science, Volume 18, Issue 11, November 2025.
ABSTRACT Valemetostat tosylate (valemetostat) is an oral, potent, dual inhibitor of enhancer of zeste homolog (EZH)2/1, under investigation in non‐Hodgkin lymphomas (NHLs) and solid tumors. In vitro, it inhibits cytochrome P450 3A (CYP3A) and P‐glycoprotein (P‐gp) when combined with sensitive CYP3A or P‐gp substrates.
Masaya Tachibana, Steven Horwitz, Eric Jacobsen, Francine Foss, Pamela Allen, Pierluigi Porcu, Tatyana Feldman, Jia Ruan, Jonathan E. Brammer, Jie Wang, Shinichi Inaba, Yuka Iko, Keiko Nakajima, Yasuyuki Kakurai, Noriaki Kitami, Yang Chen, Yvonne Lau   +16 more
wiley   +1 more source

Annotation Enrichment Analysis: An Alternative Method for Evaluating the Functional Properties of Gene Sets [PDF]

, 2013
Gene annotation databases (compendiums maintained by the scientific community that describe the biological functions performed by individual genes) are commonly used to evaluate the functional properties of experimentally derived gene sets.
Girvan, Michelle, Glass, Kimberly
core   +2 more sources

A Case of Angioimmunoblastic T-Cell Lymphoma

Journal of Clinical and Diagnostic Research
Angioimmunoblastic T-cell Lymphoma (AITL) is a rare type of peripheral T-cell lymphoma characterised by an aggressive clinical course and a poor response to current therapies. There is currently no standard of care for treatment.
Kanchan Dasharthrao Devde, Amol Gajanan Andhale, Amol Shankar Dongre, Himanshi Kaushik, Prerna Tekulware   +4 more
doaj   +1 more source

The Use of Infliximab to Control Recurrent Cytokine Storms in EBV-Associated Angioimmunoblastic Lymphoma and Hemophagocytic Syndrome [PDF]

, 2012
Introduction: Chronic active Epstein-Barr virus infection (CAEBV) has been implicated in several diseases including hemophagocytic lymphohistiocytosis (EBV-HLH) and lymphomas including Angioimmunoblastic T cell lymphoma.
Alpdogan, Onder, Besa, Emmanuel, Gaballa, Sameh   +2 more
core   +1 more source