Results 71 to 80 of about 14,294,829 (187)

Peripheral T‐Cell Lymphomas in Southern Taiwan: Epidemiology, Treatment Patterns, and Long‐Term Outcomes

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Peripheral T‐cell lymphomas (PTCLs) are heterogeneous neoplasms with poor prognosis and marked geographic variation. Data from Taiwan remain limited. We conducted a 15‐year retrospective cohort study of 249 patients diagnosed with PTCL at two major centers in southern Taiwan between 2010 and 2024 to characterize regional epidemiology, real ...
Bo‐Yu Huang, Li‐Chang Chang, Sheng‐Yen Hsiao, Ya‐Ping Chen, Sin‐Syue Li, Pei‐An Fu, Chen Chang, Kung‐Chao Chang, Tsai‐Yun Chen, Ya‐Ting Hsu   +9 more
wiley   +1 more source

Mosunetuzumab Successfully Treated Rituximab‐Refractory Lymphoma‐Associated Protein‐Losing Enteropathy With Concomitant Immune Thrombocytopenia in Follicular Lymphoma: A Case Report

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Protein‐losing enteropathy (PLE) is a rare but potentially severe complication of malignant lymphoma characterized by excessive gastrointestinal loss of plasma proteins, leading to hypoalbuminemia, edema, and serous effusions. We report a case of follicular lymphoma complicated by severe PLE and concomitant immune thrombocytopenia (ITP ...
Takashi Matsunaga, Naohi Sahara, Mai Mizusawa, Yukiko Miura, Seiichiro Kobayashi, Tomoki Fujii, Nobuhiro Oono   +6 more
wiley   +1 more source

Severe Adult HLH/MAS With SPTCL‐Like Panniculitis: A Phenotype‐Guided, Resource‐Adapted Therapeutic Strategy Without Cytotoxic Therapy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract illustrating the phenotype‐guided therapeutic approach in severe adult HLH/MAS with SPTCL‐like panniculitis, demonstrating clinical and biochemical response following sequential treatment with therapeutic plasma exchange, intravenous immunoglobulin, and cyclosporine.
Hatem Mousa Taha, Omar Marouf, Khaled Hatem Taha   +2 more
wiley   +1 more source

Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma

Haematologica, 2007
Background and Objectives In the present paper we report that SAP, an intracytoplasmic molecule that is involved in cell signaling, is an immunohistologic marker for germinal center T cells in paraffin-embedded tissue.
Giovanna Roncador, José-Francisco García Verdes-Montenegro, Sara Tedoldi, Jennifer C. Paterson, Wolfram Klapper, Erica Ballabio, Lorena Maestre, Stefano Pileri, Martin-Leo Hansmann, Miguel A. Piris, David Y. Mason, Teresa Marafioti   +11 more
doaj   +1 more source

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 9, May 2026.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Angioimmunoblastic T-cell Lymphoma: A Case Report

Pakistan Journal of Medicine and Dentistry
Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive type of non-Hodgkin's lymphoma (NHL) that is mostly diagnosed in elderly patients. Its non-specific clinical presentation (lymphadenopathy, fever, night sweats, weight loss, generalized ...
Sundus Nasim, Dua Azim, Farheen Malik, Faryal Tahir, Zehra Ashraf, Abdul Qayyum   +5 more
doaj   +1 more source

Granulomatous Vasculitis: An Unusual Manifestation of Metastatic Crohn’s Disease

Australasian Journal of Dermatology, Volume 67, Issue 5, Page e333-e334, August 2026.
Ethan Wei Min Lee, Helen Yiling Sun, Christopher W. Toon, Lachlan Andrew Byth   +3 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration

British Journal of Haematology, Volume 208, Issue 5, Page 1525-1534, May 2026.
Summary Mature T‐cell lymphomas comprise a heterogeneous group of aggressive non‐Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) represents a biologically distinct subtype driven by constitutive activation of ALK fusion ...
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +13 more
wiley   +1 more source

BCL2 expression in CD105 positive neoangiogenic cells and tumor progression in angioimmunoblastic T-cell lymphoma. [PDF]

, 2012
International audienceThe angiogenic microenvironment has been known to be a component of angioimmunoblastic T-cell lymphoma since its initial characterization.
Zhao, Wei-Li, Wang, Li, Janin, Anne, Leboeuf, Christophe, Loisel-Ferreira, Irmine, Ratajczak, Philippe, Brière, Josette, Thiéblemont, Catherine   +7 more
core   +1 more source