Results 81 to 90 of about 99,753 (275)

RHOA G17V induces T follicular helper cell specification and involves angioimmunoblastic T-cell lymphoma via upregulating the expression of PON2 through an NF-κB-dependent mechanism

open access: yesOncoimmunology, 2022
Angioimmunoblastic T-cell lymphoma (AITL) is a malignant hematologic tumor arising from T follicular helper (Tfh) cells. High-throughput genomic sequencing studies have shown that AITL is characterized by a novel highly recurring somatic mutation in RHOA,
Fenglian Que   +5 more
semanticscholar   +1 more source

Loss of 5-hydroxymethylcytosine is a frequent event in peripheral T-cell lymphomas. [PDF]

open access: yes, 2017
International ...
Bernard, O.A.   +12 more
core   +2 more sources

Association Between Moraxella catarrhalis and Nodular Lymphocyte‐Predominant Hodgkin Lymphoma

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Nodular lymphocyte‐predominant Hodgkin Lymphoma (NLPHL) may be an antigen‐driven malignancy. Recent studies demonstrated that in NLPHL patients, lymphoma B‐cell receptor can bind proteins derived from Moraxella catarrhalis (MC) and Rothia mucilaginosa (RM). We examined whether MC and RM can be detected in NLPHL lymph nodes.
Izidore S. Lossos   +7 more
wiley   +1 more source

Clonal haematopoiesis: A common progenitor for cytotoxic peripheral T‐cell lymphoma and angioimmunoblastic T‐cell lymphoma

open access: yesBritish Journal of Haematology
Recent studies have shown that follicular helper T‐cell lymphoma of angioimmunoblastic type (AITL), the most common nodal peripheral T‐cell lymphoma (PTCL), frequently arises in a background of clonal haematopoiesis (CH), a preneoplastic condition ...
Antonio Vogelsberg   +7 more
semanticscholar   +1 more source

Germline defects of familial haemophagocytic lymphohistiocytosis—Related genes may represent a predisposing factor for mature T‐ and natural killer‐cell lymphoma

open access: yesBritish Journal of Haematology, EarlyView.
Summary Peripheral T‐cell lymphoma (PTCL) is relatively prevalent in Asian populations. Previous studies suggest that germline mutations in familial haemophagocytic lymphohistiocytosis (FHL)‐related genes may predispose individuals to lymphoproliferative disorders.
Chong Wei   +4 more
wiley   +1 more source

Nodal peripheral T‐cell lymphoma in Finland between 2007 and 2019: Incidence, late morbidity and survival

open access: yesBritish Journal of Haematology, EarlyView.
Summary Data on late morbidity and survival in nodal peripheral T‐cell lymphoma (PTCL) are scarce. This study investigated the incidence, subtype distribution, late morbidity and survival outcomes of nodal PTCL in Finland. The study compared 998 patients with nodal PTCL diagnosed between 2007 and 2019 with matched controls.
Anu Partanen   +7 more
wiley   +1 more source

Angioimmunoblastic T Cell Lymphoma Mimicking Chronic Urticaria

open access: yesCase Reports in Medicine, 2016
Angioimmunoblastic T cell lymphoma (AITL) is a rare but distinct type of T cell lymphoma with an aggressive course and high mortality. Most patients are diagnosed late in the disease and usually present with generalized lymphadenopathy.
Mohleen Kang   +3 more
doaj   +1 more source

Non-ST Elevation MI as a Unique Presentation of Angioimmunoblastic T-cell Lymphoma [PDF]

open access: yes, 2012
Case A 61-year-old Chinese female with a history of hypertension, hyperlipidemia, asthma, and gastroesophageal reflux disease presented with four days of chest pressure that radiated to her left arm and jaw.
Chandra, MD, Avinash   +4 more
core   +2 more sources

Flow Cytometric Assessment of TRBC1 Expression for the Diagnosis of T‐Cell Lymphoma: Clinical Utility and Pitfalls Related to T‐Cell Clones of Uncertain Significance

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background T‐cell receptor constant beta chain 1 (TRBC1) has emerged as a potential clonal marker for T‐cell lymphoma. This study evaluated TRBC1 expression using flow cytometry in healthy individuals and various clinical specimens, assessing its clinical utility in the diagnosis of T‐cell lymphomas.
SooHo Yu   +4 more
wiley   +1 more source

Hypercalcemia as a rare presentation of angioimmunoblastic T cell lymphoma: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Angioimmunoblastic T cell lymphoma is a rare malignancy, accounting for only 2% of all non-Hodgkin lymphomas, first described in the 1970s and subsequently accepted as a distinct entity in the current World Health Organization classification ...
Sana Chams   +4 more
doaj   +1 more source

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