Results 171 to 180 of about 275,373 (195)

Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events

Current Opinion in Lipidology, 2010
Angiopoietin-like proteins (Angptls) comprise a family of secreted glycoproteins with high homology to angiopoietins which are important regulators of angiogenesis. Angptl3 and Angptl4 inhibit lipoprotein lipase in mice. This article reviews recent human studies on Angptls and their effects on lipoprotein profiles and cardiovascular disease.Population ...
Takashi, Miida, Satoshi, Hirayama
openaire   +2 more sources

Genetics and regulation of angiopoietin-like proteins 3 and 4

Current Opinion in Lipidology, 2006
Lipoprotein lipase activity in a given tissue is the rate limiting step for the uptake of triglyceride-derived fatty acids. Imbalances in the partitioning of fatty acids have major metabolic consequences. Given the central role of lipoprotein lipase in energy metabolism, the discovery of new molecules that affect the activity of lipoprotein lipase ...
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Serum angiopoietin-like protein 3 concentrations in rheumatic diseases

European Journal of Dermatology, 2012
Angiopoietin-like protein 3 (Angptl3) is one of the angiogenic cytokines that stimulates endothelial cell adhesion, migration, and neovascularization. No link has been established between Angptl3 and rheumatic diseases such as systemic sclerosis or dermatomyositis (DM).
Yasuyo, Hayashi, Masatoshi, Jinnin, Takamitsu, Makino, Ikko, Kajihara, Katsunari, Makino, Noritoshi, Honda, Wakana, Nakayama, Kuniko, Inoue, Satoshi, Fukushima, Hironobu, Ihn   +9 more
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Structure and Function of Angiopoietin-like Protein 3 (ANGPTL3) in Atherosclerosis

Current Medicinal Chemistry, 2020
Background: Angiopoietin-Like Proteins (ANGPTLs) are structurally related to the angiopoietins. A total of eight ANGPTLs (from ANGPTL1 to ANGPTL8) have been identified so far. Most ANGPTLs possess multibiological functions on lipid metabolism, atherosclerosis, and cancer.
openaire   +2 more sources

Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity

Heliyon, 2021
Yan Q Chen, Robert W Siegel, Mariam Ehsani   +2 more
exaly  

Angiopoietin‐2 and angiopoietin‐like 4 protein provide prognostic information in patients with suspected acute coronary syndrome

Journal of Internal Medicine, 2021
Reidun Aarsetøy, Thor Ueland, Pal Aukrust   +2 more
exaly  

Inhibition of angiopoietin-like protein 3 as a target for managing hypertriglyceridemia

Current Opinion in Endocrinology, Diabetes & Obesity
Purpose of review To summarize recent advances in therapeutic strategies targeting angiopoietin-like protein 3 (ANGPTL3), a central regulator of triglyceride and remnant lipoprotein metabolism, and to discuss the potential of emerging pharmacologic approaches
Pablo, Corral, Natalia, Nardelli, Laura, Schreier   +2 more
openaire   +2 more sources

A tale of two angiopoietin-like proteins

Current Opinion in Lipidology, 2007
openaire   +2 more sources

Broadening the Scope of Dyslipidemia Therapy by Targeting APOC3 (Apolipoprotein C3) and ANGPTL3 (Angiopoietin-Like Protein 3)

Arteriosclerosis, Thrombosis, and Vascular Biology, 2023
Henry N Ginsberg, Ira J Goldberg
exaly  

Changes in serum levels of angiopoietin-like protein-8 and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 after ezetimibe therapy in patients with dyslipidemia

Clinica Chimica Acta, 2020
Akihito Ideishi, Yasunori Suematsu, Kohei Tashiro   +2 more
exaly