Results 91 to 100 of about 27,286 (132)

Effects of fenofibrate on angiopoietin-like 3/4/8 proteins and apolipoprotein A5. [PDF]

open access: yesJ Lipid Res
Yang Y   +13 more
europepmc   +1 more source

Structure and Function of Angiopoietin-like Protein 3 (ANGPTL3) in Atherosclerosis

Current Medicinal Chemistry, 2020
Background: Angiopoietin-Like Proteins (ANGPTLs) are structurally related to the angiopoietins. A total of eight ANGPTLs (from ANGPTL1 to ANGPTL8) have been identified so far. Most ANGPTLs possess multibiological functions on lipid metabolism, atherosclerosis, and cancer.
Xinjie Lu
exaly   +3 more sources

Pentraxin-3, Angiopoietin-Like Protein-3, Angiopoietin-Like Protein-4 and Angiopoietin-Like Protein-8 Levels in Morbid Obese Children [PDF]

open access: yesMed One, 2017
A low-grade inflammatory state accompanies obesity and metabolic syndrome (MetS), which are risk factors for cardiovascular diseases (CVD) in children’s future lives. The aim of this study is to investigate possible associations of pentraxin 3 (PTX3), a promising new marker for CVDs, with angiopoietin-like proteins (ANGPTL) in morbid obese (MO ...
exaly   +2 more sources

Angiopoietin-like 3: An important protein in regulating lipoprotein levels

Best Practice & Research Clinical Endocrinology & Metabolism, 2023
ANGPTL3 has emerged as a therapeutic target whose inhibition results in profound reductions of plasma lipids, including atherogenic triglyceride-rich lipoproteins and low-density lipoprotein cholesterol. The identification of ANGPTL3 deficiency as a cause of familial combined hypolipidemia in humans hastened the development of anti-ANGPTL3 therapeutic ...
Kendall H, Burks   +3 more
openaire   +2 more sources

Familial combined hypolipidemia: angiopoietin-like protein-3 deficiency

Current Opinion in Lipidology, 2020
Purpose of review Angiopoietin-like protein-3 (ANGPTL3) is emerging as a key player in lipoprotein transport with an expanding role on fatty acid and glucose metabolism. Its deficiency is associated with a favorable metabolic profile.
Arca M., D'Erasmo L., Minicocci I.
openaire   +2 more sources

The angiopoietin-like protein 3

Current Opinion in Lipidology, 2013
Cumulating evidence are revealing roles of angiopoietin-like proteins (ANGPTLs) in lipid, glucose, and energy metabolism. In this review, we discuss the recent developments in understanding the specific role in metabolic processes of the liver-derived ANGPTL3.Several groups have reported clinical and metabolic characterization of individuals with loss ...
ARCA, Marcello   +2 more
openaire   +3 more sources

Response of Angiopoietin-like Proteins 3 and 4 to Hemodialysis

The International Journal of Artificial Organs, 2014
Background/Aim Patients on chronic hemodialysis (cHD) have decreased activity of lipoprotein lipase (LPL). Angiopoietin-like proteins (ANGPTL) 3 and 4 have been shown to inactivate LPL. The aim of this study was to investigate the levels of the ANGPTLs in plasma of cHD-patients and to evaluate if cHD may alter ...
Dana, Mahmood   +4 more
openaire   +2 more sources

Serum angiopoietin-like protein 3 concentrations in rheumatic diseases

European Journal of Dermatology, 2012
Angiopoietin-like protein 3 (Angptl3) is one of the angiogenic cytokines that stimulates endothelial cell adhesion, migration, and neovascularization. No link has been established between Angptl3 and rheumatic diseases such as systemic sclerosis or dermatomyositis (DM).
Yasuyo, Hayashi   +9 more
openaire   +2 more sources

Evaluation of angiopoietin-like protein 3 (ANGPTL3) levels in polycystic ovary syndrome

Life Sciences, 2020
Angiopoietin-like protein 3 (ANGPTL3) is recognized as a regulator of lipid metabolism. However, little is known about its association with insulin resistance in polycystic ovary syndrome (PCOS) setting. The present study aimed to investigate the serum levels of ANGPTL3 and adiponectin in PCOS women compared to healthy controls.In this study, a total ...
Akram, Vatannejad   +7 more
openaire   +2 more sources

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