Results 181 to 190 of about 24,454,690 (224)
Angiopoietin-Like 4 Induces Upregulation of VEGF and sVCAM1 Through JNK/c-Jun and JAK2/STAT5 Signaling Pathways. [PDF]
Invest Ophthalmol Vis SciOsorio DL +5 more
europepmc +1 more source
Association Between Serum ANGPTL8 Levels and PCOS and Its Clinical Utility in Diagnosis. [PDF]
J Obstet Gynaecol ResWang Y +6 more
europepmc +1 more source
Familial combined hypolipidemia: angiopoietin-like protein-3 deficiency
Current Opinion in Lipidology, 2020 Purpose of review Angiopoietin-like protein-3 (ANGPTL3) is emerging as a key player in lipoprotein transport with an expanding role on fatty acid and glucose metabolism. Its deficiency is associated with a favorable metabolic profile.
Arca M., D'Erasmo L., Minicocci I.
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Targeting Triglycerides: The Rise of Apolipoprotein C3 and Angiopoietin-Like Protein 3 Inhibitors
American Journal of Cardiovascular DrugsHypertriglyceridemia has been proposed as a risk factor for atherosclerotic cardiovascular disease (ASCVD). Triglycerides (TG) are viewed as a marker for remnant cholesterol in triglyceride-rich lipoproteins, as this remnant cholesterol has been identified as a causal risk factor for ASCVD. The limited number of effective treatments for elevated TG has
Taha Mansoor +11 more
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Angiopoietin-like 3: An important protein in regulating lipoprotein levels
Best Practice & Research Clinical Endocrinology & Metabolism, 2023ANGPTL3 has emerged as a therapeutic target whose inhibition results in profound reductions of plasma lipids, including atherogenic triglyceride-rich lipoproteins and low-density lipoprotein cholesterol. The identification of ANGPTL3 deficiency as a cause of familial combined hypolipidemia in humans hastened the development of anti-ANGPTL3 therapeutic ...
Kendall H, Burks +3 more
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Angiopoietin-like 2 Protein and Hidradenitis Suppurativa: A New Biomarker for Disease Severity [PDF]
Biomedicines, 2023 Hidradenitis suppurativa (HS) is a chronic inflammatory disease whose pathogenesis is not fully understood at present. The role of proinflammatory cytokines, several adipokines, retinol-binding protein 4, angiopoietin-2 and other molecules has been ...
Jose Luis Hernandez +2 more
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The angiopoietin-like protein 3
Current Opinion in Lipidology, 2013Cumulating evidence are revealing roles of angiopoietin-like proteins (ANGPTLs) in lipid, glucose, and energy metabolism. In this review, we discuss the recent developments in understanding the specific role in metabolic processes of the liver-derived ANGPTL3.Several groups have reported clinical and metabolic characterization of individuals with loss ...
ARCA, Marcello +2 more
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Response of Angiopoietin-like Proteins 3 and 4 to Hemodialysis
The International Journal of Artificial Organs, 2014Background/Aim Patients on chronic hemodialysis (cHD) have decreased activity of lipoprotein lipase (LPL). Angiopoietin-like proteins (ANGPTL) 3 and 4 have been shown to inactivate LPL. The aim of this study was to investigate the levels of the ANGPTLs in plasma of cHD-patients and to evaluate if cHD may alter ...
Dana, Mahmood +4 more
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Serum angiopoietin-like protein 3 concentrations in rheumatic diseases
European Journal of Dermatology, 2012Angiopoietin-like protein 3 (Angptl3) is one of the angiogenic cytokines that stimulates endothelial cell adhesion, migration, and neovascularization. No link has been established between Angptl3 and rheumatic diseases such as systemic sclerosis or dermatomyositis (DM).
Yasuyo, Hayashi +9 more
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