Results 181 to 190 of about 94,755 (223)

Elevated ANGPTL8 (Angiopoietin-Like Protein 8) Levels as a Novel Predictor of Atherosclerosis in Type 2 Diabetes: Beyond Lipid Metabolism. [PDF]

J Am Heart Assoc
Ye H, Zhu Q, Zong Q, Luo S, Ji Z, Zhang R, Zou H.   +6 more
europepmc   +1 more source

Effect of empagliflozin on urinary albumin excretion and hypoxic biomarkers in early diabetic kidney disease: A randomised double-blind, placebo-controlled trial. [PDF]

Diabetes Obes Metab
Makino H, Kasahara M, Takashima R, Kasama S, Ozu N, Park H, Chen Q, Tsuruya K, Tochiya M, Omura-Ohata Y, Tamanaha T, Noguchi M, Aiba T, Yoshihara F, Hosoda K.   +14 more
europepmc   +1 more source

Familial combined hypolipidemia: angiopoietin-like protein-3 deficiency

Current Opinion in Lipidology, 2020
Purpose of review Angiopoietin-like protein-3 (ANGPTL3) is emerging as a key player in lipoprotein transport with an expanding role on fatty acid and glucose metabolism. Its deficiency is associated with a favorable metabolic profile.
Arca M., D'Erasmo L., Minicocci I.
openaire   +3 more sources

The angiopoietin-like protein 3

Current Opinion in Lipidology, 2013
Cumulating evidence are revealing roles of angiopoietin-like proteins (ANGPTLs) in lipid, glucose, and energy metabolism. In this review, we discuss the recent developments in understanding the specific role in metabolic processes of the liver-derived ANGPTL3.Several groups have reported clinical and metabolic characterization of individuals with loss ...
ARCA, Marcello, Ilenia Minicocci, MARANGHI, MARIANNA   +2 more
openaire   +4 more sources

Evaluation of angiopoietin-like protein 3 (ANGPTL3) levels in polycystic ovary syndrome

Life Sciences, 2020
Angiopoietin-like protein 3 (ANGPTL3) is recognized as a regulator of lipid metabolism. However, little is known about its association with insulin resistance in polycystic ovary syndrome (PCOS) setting. The present study aimed to investigate the serum levels of ANGPTL3 and adiponectin in PCOS women compared to healthy controls.In this study, a total ...
Akram, Vatannejad, Fouzieh, Salimi, Nariman, Moradi, Fatima Zahraa, Fouani, Zahra, Zandieh, Soheila, Ansaripour, Asie, Sadeghi, Reza, Fadaei   +7 more
openaire   +3 more sources

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Molecular characterization and expression of angiopoietin-like protein 3 in the chicken, Gallus gallus

General and Comparative Endocrinology, 2008
Angiopoietin-like protein 3 (ANGPTL3) is a 70 kDa secretory glycoprotein, which has been identified as a plasma triacylglycerol (TG)-increasing factor in KK/San mice. In this study, we have characterized the expression profile and activity of ANGPTL3 in the chicken, Gallus gallus.
Kan Sato, Yukio Akiba
exaly   +3 more sources

Targeting Triglycerides: The Rise of Apolipoprotein C3 and Angiopoietin-Like Protein 3 Inhibitors

American Journal of Cardiovascular Drugs
Hypertriglyceridemia has been proposed as a risk factor for atherosclerotic cardiovascular disease (ASCVD). Triglycerides (TG) are viewed as a marker for remnant cholesterol in triglyceride-rich lipoproteins, as this remnant cholesterol has been identified as a causal risk factor for ASCVD. The limited number of effective treatments for elevated TG has
Taha Mansoor, Vijay Nambi, Sachin Parikh, Arunima Misra, Mahmoud Ismayl, Claire Sullivan, Laurence Sperling, Salim S. Virani, Mahmoud Al Rifai, Santhosh K. G. Koshy, Dmitry Abramov, Abdul Mannan Khan Minhas   +11 more
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Angiopoietin-Like 3 Protein Inhibition: A New Frontier in Lipid-Lowering Treatment

Cardiology in Review, 2019
Angiopoietin-like 3 protein (ANGPTL3) is an inhibitor of both lipoprotein lipase and endothelial lipase in humans. Population studies indicate a relationship between loss of function mutations in ANGPTL3 and favorable reductions in triglycerides and non- high-density lipoprotein cholesterol.
William, Lang, William H, Frishman
openaire   +3 more sources

Elevated serum angiopoietin-like protein 6 in women with subsequent pregnancy-induced hypertension: a preliminary study

Hypertension in Pregnancy, 2013
Matti J Tikkanen, Risto Kaaja
exaly   +2 more sources

Angiopoietin-like 3: An important protein in regulating lipoprotein levels

Best Practice & Research Clinical Endocrinology & Metabolism, 2023
ANGPTL3 has emerged as a therapeutic target whose inhibition results in profound reductions of plasma lipids, including atherogenic triglyceride-rich lipoproteins and low-density lipoprotein cholesterol. The identification of ANGPTL3 deficiency as a cause of familial combined hypolipidemia in humans hastened the development of anti-ANGPTL3 therapeutic ...
Kendall H, Burks, Debapriya, Basu, Ira J, Goldberg, Nathan O, Stitziel   +3 more
openaire   +2 more sources