Results 101 to 110 of about 4,326 (177)

Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness.

open access: yes, 2006
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hypoxia in both tumor and endothelial cells as well as in hypoxic perinecrotic areas of numerous cancers.
Mir, Lluis, M.   +12 more
core   +1 more source

Diverse roles of angiopoietin-like 4 : a literature review.

open access: yes, 2011
Angiopoietin-like (ANGPTL) proteins are a protein family structurally alike to angiopoietins, possessing analogous N-terminal coiled-coil and C-terminal fibrinogen-like domains (FLDs).
Chin, Alison Hwee Fang.
core  

The Characterization of Angiopoietin-like Protein 4 Overexpression in Triple Negative Breast Cancer

open access: yes, 2021
Triple Negative Breast Cancer (TNBC) is highly invasive and metastatic with approximately 15% of patients developing liver metastases. The primary treatment of metastatic TNBC is chemotherapy, however, there is an increased chance of resistance to this ...
Simeon, Jodi
core  

Adipocytes-induced ANGPTL4/KLF4 axis drives glycolysis and metastasis in triple-negative breast cancer

open access: yesJournal of Experimental & Clinical Cancer Research
Background The adipocyte-rich tumor microenvironment (TME) is recognized as a key factor in promoting cancer progression. A distinct characteristic of peritumoral adipocytes is their reduced lipid content and the acquisition of a proinflammatory ...
Dou Yin   +10 more
doaj   +1 more source

The Role of Angiopoietin-like 4 in Lipid Homeostasis [PDF]

open access: yes, 2012
The Role of Angiopoietin-like 4 in Lipid HomeostasisbyNora Elizabeth Forbes GrayDoctor of Philosophy in Molecular and Biochemical NutritionUniversity of California, BerkeleyProfessor Jen-Chywan Wang, ChairAlterations in the regulation of lipid ...
Gray, Nora
core  

Role of angiopoietin-like 4 in tumor growth.

open access: yes, 2011
Cancer is a leading cause of death worldwide. Tumor cells exploit various signaling molecules to promote their growth and metastasis. The angiopoietin-like 4 protein (ANGPTL4) has well-studied roles in metabolism, yet its role in cancer biology remains ...
Zhu, Pengcheng.
core   +1 more source

Serum Angiopoietin‐Like Protein 4 as a Biomarker for Acute Ischemic Stroke Severity and Dynamic Changes

open access: yesBrain and Behavior
Background Angiopoietin‐like protein 4 (ANGPTL4) is critical for vascular integrity and reducing inflammation in ischemic and hypoxic brain injuries. However, limited studies have evaluated ANGPTL4's role in acute ischemic stroke (AIS) assessment, and ...
Fang Guo   +6 more
doaj   +1 more source

Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue

open access: yes, 2018
Background: Elevated plasma triglycerides are increasingly viewed as a causal risk factor for coronary artery disease. One protein that raises plasma triglyceride levels and that has emerged as a modulator of coronary artery disease risk is angiopoietin ...
Schutte, Sophie   +6 more
core   +1 more source

The role of angiopoietin-like 4 in skin wound repair.

open access: yes, 2011
A dynamic cell-matrix interaction is crucial for a rapid cellular response to changes in the environment. Using mice deficient in angiopoietin-like 4 (ANGPTL4) either by gene ablation or immuno-neutralization, we show that ANGPTL4 is important for the ...
Goh, Yan Yih.
core   +1 more source

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