Results 101 to 110 of about 19,335,566 (141)

Angiopoietin‐Like Protein 4 Is a High‐Density Lipoprotein (HDL) Component for HDL Metabolism and Function in Nondiabetic Participants and Type‐2 Diabetic Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundANGPTL4 (angiopoietin‐like protein 4) is a LPL (lipoprotein lipase) inhibitor and is present in high‐density lipoprotein (HDL). However, it is not defined whether ANGPTL4 in HDLs could affect HDL metabolism and function in type 2 diabetes ...
Long‐Yan Yang, Cai‐Guo Yu, Xu‐Hong Wang, Sha‐Sha Yuan, Li‐Jie Zhang, Jia‐Nan Lang, Dong Zhao, Ying‐Mei Feng   +7 more
doaj   +1 more source

Novel triglyceride-lowering therapies to reduce the risk of acute pancreatitis in hypertriglyceridaemia: a protocol for systematic review and meta-analysis

BMJ Open
Introduction Hypertriglyceridaemia is a major risk factor and rising aetiology for acute pancreatitis (AP), a condition associated with significant morbidity and mortality.
Wei Huang, John Windsor, Na Shi, Robert Sutton, Wenhua He, Rajarshi Mukherjee, Shiyu Liu, Jingwen Rao, Yongzi Wu, Wenjuan Luo   +9 more
doaj   +1 more source

Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis

, 2020
Nickel (Ni), which is a carcinogenic workplace hazard, increases the risk of lung cancer. Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine that is involved in both angiogenesis and metastasis, but its role in lung cancer is still not ...
Wen-Cheng Hsu, Hui-Chun Tai, Yu-Ting Kang, Kun-Tu Yeh, Hui-Ting Hsu, Chu-Chyn Ou, Jiunn-Liang Ko   +6 more
core   +1 more source

The role of angiopoietin-like protein 4 in phenylephrine-induced cardiomyocyte hypertrophy

, 2019
Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional secreted protein that can be induced by fasting, hypoxia and glucocorticoids. ANGPTL4 has been associated with a variety of diseases; however, the role of ANGPTL4 in cardiac hypertrophy remains ...
Yugang Dong, Yu Sun, Chen Liu, Ruicong Xue, Bin Dong, Jun Liu, Yi Li, Longyun Peng, Huiling Huang   +8 more
core   +1 more source

Increased Angiopoietin Like Protein 4 (Angptl4) Is Associated With Higher Concentration Of Ldl- Triglycerides In Type 2 Diabetes [PDF]

Atherosclerosis, 2019
Y. Ito, H. Nagaike
openaire   +1 more source

Diverse roles of angiopoietin-like 4 : a literature review.

, 2011
Angiopoietin-like (ANGPTL) proteins are a protein family structurally alike to angiopoietins, possessing analogous N-terminal coiled-coil and C-terminal fibrinogen-like domains (FLDs).
Chin, Alison Hwee Fang.
core  

Comparison of the Effect of Two Personalized Low Volume-High Intensity and Combined (Strength-Aerobic) Exercises on Angiopoietin-like Protein 4 (ANGPTL4) Serum Levels in Women with Type 2 Diabetes: A Short Report [PDF]

Journal of Rafsanjan University of Medical Sciences, 2020
M. Karami, M. Ghafari, E. Banitalebi
openaire   +1 more source

Angiopoietin-Like Protein 4 and Postprandial Skeletal Muscle Lipid Metabolism in Overweight and Obese Prediabetics

, 2016
Context: Angiopoietin-like protein 4 (ANGPTL4) decreases plasma triacylglycerol (TAG) clearance by inhibiting lipoprotein lipase (LPL) and may contribute to impairments in lipid metabolism under compromised metabolic conditions.
Goossens, Gijs H.; id_orcid, Blaak, Ellen E., Goossens, Gijs H., Jocken, Johan W., van der Kolk, Birgitta W., Kersten, Sander   +5 more
core   +1 more source

Adipocytes-induced ANGPTL4/KLF4 axis drives glycolysis and metastasis in triple-negative breast cancer

Journal of Experimental & Clinical Cancer Research
Background The adipocyte-rich tumor microenvironment (TME) is recognized as a key factor in promoting cancer progression. A distinct characteristic of peritumoral adipocytes is their reduced lipid content and the acquisition of a proinflammatory ...
Dou Yin, Nana Fang, Yaling Zhu, Xiaoqing Bao, Juan Yang, Qingyu Zhang, Ruimeng Wang, Jiahui Huang, Qibing Wu, Fang Ma, Xiaohui Wei   +10 more
doaj   +1 more source

Serum Angiopoietin‐Like Protein 4 as a Biomarker for Acute Ischemic Stroke Severity and Dynamic Changes

Brain and Behavior
Background Angiopoietin‐like protein 4 (ANGPTL4) is critical for vascular integrity and reducing inflammation in ischemic and hypoxic brain injuries. However, limited studies have evaluated ANGPTL4's role in acute ischemic stroke (AIS) assessment, and ...
Fang Guo, Chong Zheng, Tao Yang, Fang‐Wei Hu, Yan‐Gui Chen, Chia‐Wei Liou, Bin Cai   +6 more
doaj   +1 more source