Results 1 to 10 of about 5,344 (155)

Reduced angiopoietin-2 as a predictive biomarker for clomiphene citrate resistance in polycystic ovary syndrome

Journal of Human Reproductive Sciences, 2021
Background: Even though angiopoeitin-2 and interleukin (IL)-23 are known to be altered in polycystic ovary syndrome (PCOS), their association with clomiphene citrate (CC) resistance has not been studied. Aim: The objective of the study was to investigate
Luxmipratha Rajendiran, Hanumanthappa Nandeesha, Thyagaraju Chitra   +2 more
doaj   +1 more source

Basophils from allergy to cancer

Frontiers in Immunology, 2022
Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, beginning with their isolation and more recently in the ...
Remo Poto, Remo Poto, Remo Poto, Adriana Rosa Gambardella, Adriana Rosa Gambardella, Gianni Marone, Gianni Marone, Gianni Marone, Gianni Marone, John T. Schroeder, Fabrizio Mattei, Giovanna Schiavoni, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +15 more
doaj   +1 more source

Angiopoietins and prediction of vitreous hemorrhage in type 2 diabetes patients with diabetic retinopathy

Journal of Ophthalmology, 2022
Background: Various types of vitreoretinal surgery are used for the treatment of severe diabetic retinopathy (DR), with vitreous hemorrhage being a common postoperative complication. Impaired angiopoietin system function in type 2 diabetes mellitus (T2DM)
S. O. Rykov, S. Iu. Mogilevskyy, S. S. Lytvynenko, S. V. Ziablitsev   +3 more
doaj   +1 more source

Clinical Significance of Tie-2-Expressing Monocytes/Macrophages and Angiopoietins in the Progression of Ovarian Cancer—State-of-the-Art

Cells, 2022
Tumour growth and metastasis are specific to advanced stages of epithelial ovarian cancer (EOC). Tumour angiogenesis is an essential part of these processes.
Wiktoria Skiba, Dorota Suszczyk, Anna Pawłowska, Karolina Włodarczyk, Anna Pańczyszyn, Iwona Wertel   +5 more
doaj   +1 more source

Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis

Cells, 2020
Angiopoietin-1 (Ang-1) is a ligand of Tie-2 receptors that promotes angiogenesis. It has been established that regulatory loops exist between angiogenic growth factors and distinct pro or anti-angiogenic miRNAs, but the nature and the roles of Ang-1 ...
Sharon Harel, Veronica Sanchez-Gonzalez, Raquel Echavarria, Dominique Mayaki, Sabah NA Hussain   +4 more
doaj   +1 more source

Type I Interferons induce endothelial destabilization in Systemic Lupus Erythematosus in a Tie2-dependent manner

Frontiers in Immunology, 2023
Endothelial cell (EC) dysfunction is a hallmark of Systemic Lupus Erythematosus (SLE) and Tie2 is a receptor essential for vascular stability. Inflammatory processes promote inhibition of Tie2 homeostatic activation, driving vascular dysfunction. In this
Carlos Rafael-Vidal, Carlos Rafael-Vidal, Sara Martínez-Ramos, Sara Martínez-Ramos, Beatriz Malvar-Fernández, Beatriz Malvar-Fernández, Irene Altabás-González, Irene Altabás-González, Coral Mouriño, Douglas J. Veale, Douglas J. Veale, Achilleas Floudas, Ursula Fearon, Ursula Fearon, José María Pego Reigosa, José María Pego Reigosa, Samuel García, Samuel García   +17 more
doaj   +1 more source

Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma

Frontiers in Oncology, 2017
Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers. Among them, the two clinically interrelated subtypes, proneural and mesenchymal, are the most aggressive with proneural liable ...
Aman Sharma, Aman Sharma, Ajinkya Bendre, Abir Mondal, Dattatraya Muzumdar, Naina Goel, Anjali Shiras   +6 more
doaj   +1 more source

Baseline Ang-2 Serum Levels as a Predictive Factor for Survival in NSCLC and SCLC

Life, 2022
Angiopoietin-2 (Ang-2) has been implicated in the development of several types of cancer, including lung malignancy. In the present study, we examined the impact of Ang-2 serum concentration on the development, dissemination, and 5-year overall survival ...
Asimina Nikolakopoulou, Dimitris Tsakogiannis, Flora Zagouri, Eleni Zografos, Lamprini Tzioga, Grigorios Stratakos, Nikolaos Koulouris, Konstantinos Syrigos, Garyfalia Bletsa   +8 more
doaj   +1 more source

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Nature Communications, 2017
The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific.
Martin Teichert, Laura Milde, Annegret Holm, Laura Stanicek, Nicolas Gengenbacher, Soniya Savant, Tina Ruckdeschel, Zulfiyya Hasanov, Kshitij Srivastava, Junhao Hu, Stella Hertel, Arne Bartol, Katharina Schlereth, Hellmut G. Augustin   +13 more
doaj   +1 more source

Mechanisms of angiogenesis in chronic inflammatory liver disease

Annals of Hepatology, 2007
Intrahepatic hypoxia may occur during the inflammatory and fibrotic processes that characterize several chronic liver diseases of viral and autoimmune origin.
María Chaparro, Paloma Sanz-Cameno, María Trapero-Marugán, Luisa García-Buey, Ricardo Moreno-Otero   +4 more
doaj   +1 more source