Results 21 to 30 of about 6,404 (202)

Basophils from allergy to cancer

Frontiers in Immunology, 2022
Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, beginning with their isolation and more recently in the ...
Remo Poto, Remo Poto, Remo Poto, Adriana Rosa Gambardella, Adriana Rosa Gambardella, Gianni Marone, Gianni Marone, Gianni Marone, Gianni Marone, John T. Schroeder, Fabrizio Mattei, Giovanna Schiavoni, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +15 more
doaj   +1 more source

Angiopoietins and prediction of vitreous hemorrhage in type 2 diabetes patients with diabetic retinopathy

Journal of Ophthalmology, 2022
Background: Various types of vitreoretinal surgery are used for the treatment of severe diabetic retinopathy (DR), with vitreous hemorrhage being a common postoperative complication. Impaired angiopoietin system function in type 2 diabetes mellitus (T2DM)
S. O. Rykov, S. Iu. Mogilevskyy, S. S. Lytvynenko, S. V. Ziablitsev   +3 more
doaj   +1 more source

Clinical Significance of Tie-2-Expressing Monocytes/Macrophages and Angiopoietins in the Progression of Ovarian Cancer—State-of-the-Art

Cells, 2022
Tumour growth and metastasis are specific to advanced stages of epithelial ovarian cancer (EOC). Tumour angiogenesis is an essential part of these processes.
Wiktoria Skiba, Dorota Suszczyk, Anna Pawłowska, Karolina Włodarczyk, Anna Pańczyszyn, Iwona Wertel   +5 more
doaj   +1 more source

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Nature Communications, 2017
The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific.
Martin Teichert, Laura Milde, Annegret Holm, Laura Stanicek, Nicolas Gengenbacher, Soniya Savant, Tina Ruckdeschel, Zulfiyya Hasanov, Kshitij Srivastava, Junhao Hu, Stella Hertel, Arne Bartol, Katharina Schlereth, Hellmut G. Augustin   +13 more
doaj   +1 more source

Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma

Frontiers in Oncology, 2017
Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers. Among them, the two clinically interrelated subtypes, proneural and mesenchymal, are the most aggressive with proneural liable ...
Aman Sharma, Aman Sharma, Ajinkya Bendre, Abir Mondal, Dattatraya Muzumdar, Naina Goel, Anjali Shiras   +6 more
doaj   +1 more source

Mechanisms of angiogenesis in chronic inflammatory liver disease

Annals of Hepatology, 2007
Intrahepatic hypoxia may occur during the inflammatory and fibrotic processes that characterize several chronic liver diseases of viral and autoimmune origin.
María Chaparro, Paloma Sanz-Cameno, María Trapero-Marugán, Luisa García-Buey, Ricardo Moreno-Otero   +4 more
doaj   +1 more source

Impact of Angiopoietin-2 on Kidney Diseases

Kidney Diseases, 2023
Background: Angiopoietins (Ang) are essential angiogenic factors involved in angiogenesis, vascular maturation, and inflammation. The most studied angiopoietins, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), behave antagonistically to each other in ...
Mei Li, Zoran Popovic, Chang Chu, Christoph Reichetzeder, Wolfgang Pommer, Bernhard K. Krämer, Berthold Hocher   +6 more
doaj   +1 more source

The misunderstood link between SARS-CoV-2 and angiogenesis. A narrative review

Pulmonology, 2023
Novel Coronavirus Disease 2019 (Covid-19) is associated with multi-systemic derangement, including circulatory dysfunction with features of endothelial dysfunction, microangiopathic thrombosis and angiocentric inflammation.
G. Madureira, R. Soares
doaj   +1 more source

Angiopoietins differentially influence in vitro angiogenesis by endothelial cells of different origin [PDF]

, 2011
Angiopoietins are important growth factors for vascular development and quiescence. They are promising targets for pro-or anti-angiogenic therapies in diverse pathologies, but the mechanisms of the ANGPT/TIE2 system are complex and not well understood ...
Cornillie, Pieter, Bahramsoltani, Mahtab, De Spiegelaere, Ward, Plendl, Johanna, Van Den Broeck, Wim   +4 more
core   +1 more source

Is There a Role for Basophils in Cancer?

Frontiers in Immunology, 2020
Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes.
Giancarlo Marone, Giancarlo Marone, John T. Schroeder, Fabrizio Mattei, Stefania Loffredo, Stefania Loffredo, Stefania Loffredo, Stefania Loffredo, Adriana Rosa Gambardella, Remo Poto, Remo Poto, Amato de Paulis, Amato de Paulis, Amato de Paulis, Giovanna Schiavoni, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +18 more
doaj   +1 more source