Results 21 to 30 of about 5,425 (227)

Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma

open access: yesFrontiers in Oncology, 2017
Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers. Among them, the two clinically interrelated subtypes, proneural and mesenchymal, are the most aggressive with proneural liable ...
Aman Sharma   +6 more
doaj   +1 more source

Clinical Significance of Tie-2-Expressing Monocytes/Macrophages and Angiopoietins in the Progression of Ovarian Cancer—State-of-the-Art

open access: yesCells, 2022
Tumour growth and metastasis are specific to advanced stages of epithelial ovarian cancer (EOC). Tumour angiogenesis is an essential part of these processes.
Wiktoria Skiba   +5 more
doaj   +1 more source

Angiopoietin-1/Angiopoietin-2 Ratio for Prediction of Preeclampsia [PDF]

open access: yesAmerican Journal of Hypertension, 2009
A number of different biophysical and biochemical markers have been proposed as predictors of preeclampsia. Factors involved in the angiogenic balance are suggested as candidate markers. The purpose of this prospective, longitudinal cohort study was to determine whether a ratio between Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) can be used to ...
Marie, Bolin   +6 more
openaire   +2 more sources

Mechanisms of angiogenesis in chronic inflammatory liver disease

open access: yesAnnals of Hepatology, 2007
Intrahepatic hypoxia may occur during the inflammatory and fibrotic processes that characterize several chronic liver diseases of viral and autoimmune origin.
María Chaparro   +4 more
doaj   +1 more source

Impact of Angiopoietin-2 on Kidney Diseases

open access: yesKidney Diseases, 2023
Background: Angiopoietins (Ang) are essential angiogenic factors involved in angiogenesis, vascular maturation, and inflammation. The most studied angiopoietins, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), behave antagonistically to each other in ...
Mei Li   +6 more
doaj   +1 more source

Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance

open access: yesInvestigative Opthalmology & Visual Science, 2022
Defects in the iridocorneal angle tissues, including the trabecular meshwork (TM) and Schlemm's canal (SC), impair aqueous humor flow and increase the intraocular pressure (IOP), eventually resulting in glaucoma. Activation of endothelial tyrosine kinase receptor Tie2 by angiopoietin-1 (Angpt1) has been demonstrated to be essential for SC formation ...
Kapiainen, E. (Emmi)   +4 more
openaire   +3 more sources

The misunderstood link between SARS-CoV-2 and angiogenesis. A narrative review

open access: yesPulmonology, 2023
Novel Coronavirus Disease 2019 (Covid-19) is associated with multi-systemic derangement, including circulatory dysfunction with features of endothelial dysfunction, microangiopathic thrombosis and angiocentric inflammation.
G. Madureira, R. Soares
doaj   +1 more source

Angiopoietins stimulate pancreatic islet development from stem cells

open access: yesScientific Reports, 2021
In vitro differentiation of human induced pluripotent stem cells (iPSCs) into functional islets holds immense potential to create an unlimited source of islets for diabetes research and treatment.
Soujanya S. Karanth   +4 more
doaj   +1 more source

Is There a Role for Basophils in Cancer?

open access: yesFrontiers in Immunology, 2020
Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes.
Giancarlo Marone   +18 more
doaj   +1 more source

Angiogenic inflammation and formation of necrosis in the tumor microenvironment influence patient survival after radical surgery for de novo hepatocellular carcinoma in non-cirrhosis

open access: yesWorld Journal of Surgical Oncology, 2019
Background Tumor escape mechanisms mediated in the tumor microenvironment can significantly reduce the capacity of the anti-tumor function of the immune system. TIE2-expressing monocytes (TEMs), related angiopoietins, and tumor necrosis are considered to
Georgi Atanasov   +8 more
doaj   +1 more source

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