Results 11 to 20 of about 5,344 (155)

The Significance of Angiopoietin Valency in Vascular Health and Disease [PDF]

Cells
The Angiopoietin–Tie2 pathway is a key regulator of postnatal vascular maintenance and remodeling, regulating vascular barrier function and integrity.
Yan Ting Zhao, Devon D. Ehnes, Julie Mathieu, Hannele Ruohola-Baker   +3 more
doaj   +2 more sources

Angiopoietins as biomarkers of schistosomiasis severity: a cross-sectional study [PDF]

Parasitology
Schistosomiasis, a parasitic disease caused by Schistosoma species, remains highly prevalent in tropical regions, where it contributes significantly to hepatic and vascular complications.
Rachael Lima Sobreira Coimbra, Gdayllon Cavalcante Meneses, Rosângela Lima de Freitas Galvão, Marta Cristhiany Cunha Pinheiro, Luciana Maria de Oliveira, Nicole Coelho Lope, Bruna Viana Barroso Martins, Letícia Machado de Araújo, Rebeca Yasmin Ribeiro Vieira, Reinaldo Barreto Oriá, Alice Maria Costa Martins, Elizabeth de Francesco Daher, Ângela Maria da Silva, Fernando Schemelzer de Moraes Bezerra   +13 more
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Angiopoietin‐1, Angiopoietin‐2 and Vascular Endothelial Growth Factor Levels in Canine Leishmaniosis [PDF]

Veterinary Medicine and Science
Background Canine leishmaniosis (CanL) is a zoonotic vector–borne disease and is primarily associated with systemic inflammation, endothelial dysfunction and immune dysregulation. Although angiopoietins (Ang) and vascular endothelial growth factor (VEGF)
Gamze Gultekin, Erdogan Malatyali, Evren Tileklioglu, Hatice Ertabaklar, Songul Erdogan, Gamze Sevri Ekren Asici, Asude Gulce Oryasin, Serdar Pasa, Kerem Ural, Hasan Erdogan, Mehmet Gultekin   +10 more
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Maternal serum angiopoietins levels in pre‐eclampsia and pregnancy outcomes [PDF]

Health Science Reports
Background and Aims Although the understanding of pre‐eclampsia (PE) has improved, there is still insufficient knowledge on the exact etiology and pathophysiological mechanisms.
Fidelis Bayor, Kwame Adu‐Bonsaffoh, Charles Antwi‐Boasiako   +2 more
doaj   +2 more sources

Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy [PDF]

Biomedicines
Angiopoietins are crucial growth factors for maintaining a healthy, functional endothelium. Patients with type 2 diabetes (T2D) exhibit significant levels of angiogenic markers, particularly Angiopoietin-2, which compromises endothelial integrity and is ...
Eman Alshawaf, Mohamed Abu-Farha, Anwar Mohammad, Sriraman Devarajan, Irina Al-Khairi, Preethi Cherian, Hamad Ali, Hawra Al-Matrouk, Fahd Al-Mulla, Abdulnabi Al Attar, Jehad Abubaker   +10 more
doaj   +2 more sources

Effect of Vitamin E on Serum Levels of Vascular Endothelial Growth Factor and Angiopoietin-1 in Women with Polycystic Ovary Syndrome: A Pilot Randomized, Placebo-Controlled Trial [PDF]

International Journal of Fertility and Sterility, 2021
Background: Angiogenesis disturbances are common in women with polycystic ovary syndrome (PCOS). VitaminE has antiangiogenic properties. Data on the effects of vitamin E on angiogenesis in PCOS is limited, so the currentstudy was conducted to evaluate ...
Shabnam Shirazi, Bahram Pourghassem Gargari, Azimeh Izadi, Shiva Taghizadeh, Marziyeh Parizad   +4 more
doaj   +1 more source

ETS1, ELK1, and ETV4 Transcription Factors Regulate Angiopoietin-1 Signaling and the Angiogenic Response in Endothelial Cells

Frontiers in Physiology, 2021
BackgroundAngiopoietin-1 (Ang-1) is the main ligand of Tie-2 receptors. It promotes endothelial cell (EC) survival, migration, and differentiation. Little is known about the transcription factors (TFs) in ECs that are downstream from Tie-2 receptors ...
Sharon Harel, Sharon Harel, Sharon Harel, Veronica Sanchez, Veronica Sanchez, Veronica Sanchez, Alaa Moamer, Alaa Moamer, Alaa Moamer, Javier E. Sanchez-Galan, Mohammad N. Abid Hussein, Dominique Mayaki, Dominique Mayaki, Dominique Mayaki, Mathieu Blanchette, Sabah N. A. Hussain, Sabah N. A. Hussain, Sabah N. A. Hussain   +17 more
doaj   +1 more source

Proinflammatory Endothelial Phenotype in Very Preterm Infants: A Pilot Study

Biomedicines, 2022
Very preterm infants are exposed to prenatal inflammatory processes and early postnatal hemodynamic and respiratory complications, but limited data are available about the endothelial effect of these conditions.
Giacomo S. Amelio, Livia Provitera, Genny Raffaeli, Ilaria Amodeo, Silvia Gulden, Valeria Cortesi, Francesca Manzoni, Nicola Pesenti, Matteo Tripodi, Valentina Pravatà, Caterina Lonati, Gaia Cervellini, Fabio Mosca, Giacomo Cavallaro   +13 more
doaj   +1 more source

Update Overview of the Role of Angiopoietins in Lung Cancer

Medicina, 2021
Angiogenesis is a biological process that involves the formation of new blood vessels from the existing vasculature, and it plays a fundamental role in the development and progression of several types of cancer, including lung cancer.
Dimitris Tsakogiannis, Asimina Nikolakopoulou, Flora Zagouri, Grigorios Stratakos, Konstantinos Syrigos, Eleni Zografos, Nikolaos Koulouris, Garyfalia Bletsa   +7 more
doaj   +1 more source

Autocrine role of angiopoietins during megakaryocytic differentiation. [PDF]

PLoS ONE, 2012
The tyrosine kinase Tie-2 and its ligands Angiopoietins (Angs) transduce critical signals for angiogenesis in endothelial cells. This receptor and Ang-1 are coexpressed in hematopoietic stem cells and in a subset of megakaryocytes, though a possible role
Ernestina Saulle, Raffaella Guerriero, Alessia Petronelli, Elena Coppotelli, Marco Gabbianelli, Ornella Morsilli, Isabella Spinello, Elvira Pelosi, Germana Castelli, Ugo Testa, Simona Coppola   +10 more
doaj   +1 more source