Results 1 to 10 of about 57,083 (310)

Prognostic Significance of the angiopoietin-2 for Early Prediction of Septic Shock in Severe Sepsis Patients

Future Science OA, 2022
Aim: The current study investigated the plasma levels of angiopoietin-1/-2 and their association with clinical outcomes of sepsis. Methods: Angiopoietin-1 and -2 levels were quantified in plasma from 105 patients with severe sepsis by ELISA.
Hoang Van Tong, Ngo Thu Hang, Can van Mao   +2 more
exaly   +4 more sources

ICU Admission Levels of Endothelial Biomarkers as Predictors of Mortality in Critically Ill COVID-19 Patients

Cells, 2021
Endotheliopathy is suggested to be an important feature of COVID-19 in hospitalized patients. To determine whether endotheliopathy is involved in COVID-19-associated mortality, markers of endothelial damage were assessed in critically ill COVID-19 ...
Alice G. Vassiliou, Chrysi Keskinidou, Edison Jahaj, Parisis Gallos, Ioanna Dimopoulou, Anastasia Kotanidou, Stylianos E. Orfanos   +6 more
doaj   +1 more source

Angiopoietin/Tie2 signalling and its role in retinal and choroidal vascular diseases: a review of preclinical data

Eye, 2021
The angopoietin/tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development and maintenance.
A. Joussen, F. Ricci, Liliana P. Paris, C. Korn, Carlos Quezada-Ruiz, M. Zarbin   +5 more
semanticscholar   +1 more source

Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angiopoietin-1/angiopoietin-2 ratio, and soluble angiopoietin receptor Tie-2 levels in type 2 diabetic patients with proliferative diabetic retinopathy [PDF]

International Journal of Ophthalmology, 2014
AIM: To determine the effects of laser photocoagulation on serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble angiopoietin receptor Tie-2 (Tie-2), Ang-1/Ang-2 ratio and vascular endothelial growth factor (VEGF) in patients with type ...
Qiao-Ying You, Fu-Yuan Zhuge, Qi-Qian Zhu, Xu-Wei Si   +3 more
doaj   +1 more source

Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism

Journal of Lipid Research, 2021
Triglycerides are carried in the bloodstream as the components of very low-density lipoproteins and chylomicrons. These circulating triglycerides are primarily hydrolyzed in muscle and adipose tissue by the enzyme lipoprotein lipase (LPL).
S. Kersten
semanticscholar   +1 more source

Arsenic trioxide inhibits angiogenesis of hepatocellular carcinoma after insufficient radiofrequency ablation via blocking paracrine angiopoietin-1 and angiopoietin-2

International Journal of Hyperthermia, 2022
Objectives Angiogenesis occurs during tumor progression of hepatocellular carcinoma (HCC) after insufficient radiofrequency ablation (RFA). Arsenic trioxide (ATO) shows promising therapeutic potential in advanced HCC.
Shuying Dong, Zhuxin Li, Jian Kong, Shilun Wu, Jun Gao, Wenbing Sun   +5 more
doaj   +1 more source

Angiopoietin-2 inhibition attenuates kidney fibrosis by hindering chemokine C-C motif ligand 2 expression and apoptosis of endothelial cells.

Kidney International, 2022
Plasma levels of angiopoietin-2 are increased in patients with chronic kidney disease (CKD). Moreover, mouse models of progressive kidney disease also demonstrate increased angiopoietin-2 in both plasmas and kidneys.
F. Chang, Chia-Hao Liu, An Luo, Thomas Tao-Min Huang, Ming-Hsuan Tsai, Yu-Jhen Chen, Chun-Fu Lai, Chih-Kang Chiang, Tzu-Hung Lin, Wen-Chih Chiang, Yung-Ming Chen, T. Chu, Shuei-Liong Lin   +12 more
semanticscholar   +1 more source

Insight into the Role of Angiopoietins in Ageing-Associated Diseases

Cells, 2020
Angiopoietin (Ang) and its receptor, TIE signaling, contribute to the development and maturation of embryonic vasculature as well as vascular remodeling and permeability in adult tissues.
Shin-ichiro Hayashi, Hiromi Rakugi, Ryuichi Morishita   +2 more
doaj   +1 more source

Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients

Angiogenesis, 2020
Background Coronavirus disease-2019 (COVID-19), a respiratory disease has been associated with ischemic complications, coagulation disorders, and an endotheliitis.
D. Smadja, C. Guerin, R. Chocron, N. Yatim, J. Boussier, N. Gendron, L. Khider, J. Hadjadj, Guillaume Goudot, B. Debuc, P. Juvin, C. Hauw‐Berlemont, J. Augy, N. Péron, E. Messas, B. Planquette, O. Sanchez, B. Charbit, P. Gaussem, D. Duffy, B. Terrier, T. Mirault, J. Diehl   +22 more
semanticscholar   +1 more source

Angiopoietin-Like Protein 3 (ANGPTL3) Modulates Lipoprotein Metabolism and Dyslipidemia

International Journal of Molecular Sciences, 2021
Dyslipidemia is characterized by increasing plasma levels of low-density lipoprotein-cholesterol (LDL-C), triglycerides (TGs) and TG-rich lipoproteins (TGRLs) and is a major risk factor for the development of atherosclerotic cardiovascular disorders ...
Pei-Yi Chen, Wan-Yun Gao, J. Liou, Ching-Yen Lin, Ming-Jiuan Wu, J. Yen   +5 more
semanticscholar   +1 more source