Results 1 to 10 of about 35,290 (117)

Role of Serum IL-33 in Bothrops Snakebite Victims: Linking Inflammation and Endothelial Dysfunction [PDF]

Toxins
Bothrops snakebites pose a significant public health challenge in low- and middle-income regions, often resulting in inflammation, coagulopathy, and renal complications even after antivenom therapy.
Nicole Coelho Lopes, Ranieri Sales de Souza Santos, Gdayllon Cavalcante Meneses, Leticia Machado de Araújo, Bruna Viana Barroso Martins, Katarina Maria dos Reis Araújo, Marina Coelho Feitosa, Yury Pifano Varela, Fathima Shihana, Sandra Mara Brasileiro Mota, Geraldo Bezerra da Silva Junior, Elizabeth De Francesco Daher, Polianna Lemos Moura Moreira Albuquerque, Alice Maria Costa Martins   +13 more
doaj   +2 more sources

Prognostic Significance of the angiopoietin-2 for Early Prediction of Septic Shock in Severe Sepsis Patients

Future Science OA, 2022
Aim: The current study investigated the plasma levels of angiopoietin-1/-2 and their association with clinical outcomes of sepsis. Methods: Angiopoietin-1 and -2 levels were quantified in plasma from 105 patients with severe sepsis by ELISA.
Hoang Tong, Can Van Mao, Ngo Thu Hang
exaly   +3 more sources

The Role of Angiopoietin-2 in Post-Burn Pneumonia [PDF]

European Burn Journal
Background: Pneumonia contributes to post-burn morbidity and mortality. Understanding the mechanisms that predispose burn patients to pneumonia is crucial to both stratifying patients at increased risk and developing targeted interventions.
Mary Grace Murray, Ryan M. Johnson, Abigail B. Plum, Natalia Carbajal Garcia, Kevin E. Galicia, Alexandra Brady, Madison Kipp, Irene B. Helenowski, Madison M. Tschann, Connor Guzior, Richard P. Gonzalez, Mashkoor A. Choudhry, John C. Kubasiak   +12 more
doaj   +2 more sources

ICU Admission Levels of Endothelial Biomarkers as Predictors of Mortality in Critically Ill COVID-19 Patients

Cells, 2021
Endotheliopathy is suggested to be an important feature of COVID-19 in hospitalized patients. To determine whether endotheliopathy is involved in COVID-19-associated mortality, markers of endothelial damage were assessed in critically ill COVID-19 ...
Alice G. Vassiliou, Chrysi Keskinidou, Edison Jahaj, Parisis Gallos, Ioanna Dimopoulou, Anastasia Kotanidou, Stylianos E. Orfanos   +6 more
doaj   +1 more source

Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angiopoietin-1/angiopoietin-2 ratio, and soluble angiopoietin receptor Tie-2 levels in type 2 diabetic patients with proliferative diabetic retinopathy [PDF]

International Journal of Ophthalmology, 2014
AIM: To determine the effects of laser photocoagulation on serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble angiopoietin receptor Tie-2 (Tie-2), Ang-1/Ang-2 ratio and vascular endothelial growth factor (VEGF) in patients with type ...
Qiao-Ying You, Fu-Yuan Zhuge, Qi-Qian Zhu, Xu-Wei Si   +3 more
doaj   +1 more source

Arsenic trioxide inhibits angiogenesis of hepatocellular carcinoma after insufficient radiofrequency ablation via blocking paracrine angiopoietin-1 and angiopoietin-2

International Journal of Hyperthermia, 2022
Objectives Angiogenesis occurs during tumor progression of hepatocellular carcinoma (HCC) after insufficient radiofrequency ablation (RFA). Arsenic trioxide (ATO) shows promising therapeutic potential in advanced HCC.
Shuying Dong, Zhuxin Li, Jian Kong, Shilun Wu, Jun Gao, Wenbing Sun   +5 more
doaj   +1 more source

Insight into the Role of Angiopoietins in Ageing-Associated Diseases

Cells, 2020
Angiopoietin (Ang) and its receptor, TIE signaling, contribute to the development and maturation of embryonic vasculature as well as vascular remodeling and permeability in adult tissues.
Shin-ichiro Hayashi, Hiromi Rakugi, Ryuichi Morishita   +2 more
doaj   +1 more source

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice

Biomedicines, 2023
In Duchenne muscular dystrophy (DMD), angiogenesis appears to be attenuated. Local administration of angiopoietin 1 (Ang1) has been shown to reduce inflammation, ischemia, and fibrosis in DMD mice.
Yiming Lin, Andrew McClennan, Lisa Hoffman   +2 more
doaj   +1 more source

The Angiopoietin Signaling Pathway Is Involved in Inflammatory Processes in Hospitalized COVID-19 Patients

Microorganisms, 2023
The viral agent SARS-CoV-2 clearly affects several organ systems, including the cardiovascular system. Angiopoietins are involved in vascular integrity and angiogenesis.
Rachelle P. Mendoza, Amir Momeni, Nayanendu Saha, Juwairiya Arshi, Elmer C. Gabutan, Nichole Alejandro, Alejandro Zuretti, Prem K. Premsrirut, Dimitar B. Nikolov   +8 more
doaj   +1 more source

Short-Term Outcomes of Intravitreal Faricimab Injection for Diabetic Macular Edema

Medicina, 2023
Background and Objectives: Faricimab is a novel bispecific antibody with Fab regions inhibiting both vascular endothelial growth factor-A and angiopoietin-2. Therefore, this study aimed to obtain short-term outcomes of intravitreal injection of faricimab
Sentaro Kusuhara, Maya Kishimoto-Kishi, Wataru Matsumiya, Akiko Miki, Hisanori Imai, Makoto Nakamura   +5 more
doaj   +1 more source