Results 41 to 50 of about 57,083 (310)

Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8

Journal of Lipid Research, 2021
High plasma triglyceride (TG) levels and low HDL-C levels are risk factors for atherosclerosis and cardiovascular disease. Both plasma TG and HDL-C levels are regulated in part by the circulating inhibitor, angiopoietin-like 3 (ANGPTL3). ANGPTL3 inhibits
Kelli L. Sylvers-Davie, Ashley Segura-Roman, Alicia M. Salvi, Kylie J. Schache, Brandon S. J. Davies   +4 more
semanticscholar   +1 more source

Serum angiopoietin-2 as a noninvasive diagnostic marker of stages of liver fibrosis in chronic hepatitis C patients

The Egyptian Journal of Internal Medicine, 2016
Background The process of fibrogenesis is associated with the development of disease-specific markers. The management of chronic hepatitis C (CHC) depends on the staging of liver fibrosis. Use of noninvasive methods is preferable in diagnosis and follow-
Mohamed M Makhlouf, Mahmoud A Osman, Shereen A.B. Saleh, Wael A Yousry, Mohamed L Soliman, Wahid H Doss, Fayrouz S Wahba   +6 more
doaj   +1 more source

Update Overview of the Role of Angiopoietins in Lung Cancer

Medicina, 2021
Angiogenesis is a biological process that involves the formation of new blood vessels from the existing vasculature, and it plays a fundamental role in the development and progression of several types of cancer, including lung cancer.
Dimitris Tsakogiannis, Asimina Nikolakopoulou, Flora Zagouri, Grigorios Stratakos, Konstantinos Syrigos, Eleni Zografos, Nikolaos Koulouris, Garyfalia Bletsa   +7 more
doaj   +1 more source

THE ANGIOPOIETIN/TIE PATHWAY IN RETINAL VASCULAR DISEASES: A REVIEW [67/135 characters].

Retina, 2020
PURPOSE To provide a concise overview for ophthalmologists and practicing retina specialists of available clinical evidence of manipulating the angiopoietin/tyrosine kinase with immunoglobulin-like and endothelial growth factor-like domains (Tie) pathway
J. Heier, Rishi P. Singh, C. Wykoff, K. Csaky, T. Lai, A. Loewenstein, P. Schlottmann, Liliana P. Paris, P. Westenskow, Carlos Quezada-Ruiz   +9 more
semanticscholar   +1 more source

Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling

Endocrinology, 2021
Pericytes regulate vascular development, stability, and quiescence; their dysfunction contributes to diabetic retinopathy. To explore the role of insulin receptors in pericyte biology, we created pericyte insulin receptor knockout mice (PIRKO) by ...
N. Warmke, Fiona Platt, Alexander F. Bruns, Claire H. Ozber, N. Haywood, Yilizila Abudushalamu, C. Slater, V. Palin, P. Sukumar, S. Wheatcroft, N. Yuldasheva, M. Kearney, K. Griffin, R. Cubbon   +13 more
semanticscholar   +1 more source

Cellular and molecular aspects of diabetic nephropathy; the role of VEGF-A

Nefrología (English Edition), 2015
The prevalence of diabetes mellitus increased during the last century and it is estimated that 45% of the patients are not diagnosed. In South America the prevalence of diabetes and chronic kidney disease (CKD) increased, with a great disparity among the
Katherine Carranza, Dolores Veron, Alicia Cercado, Noemi Bautista, Wilson Pozo, Alda Tufro, Delma Veron   +6 more
doaj   +1 more source

Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

Journal of Lipid Research, 2019
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a widespread recognition of adipose tissue as an endocrine organ.
Jan-Bernd Funcke, Philipp E. Scherer
doaj   +1 more source

Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis

Biomolecules, 2013
The main function of the lymphatic system is to control and maintain fluid homeostasis, lipid transport, and immune cell trafficking. In recent years, the pathological roles of lymphangiogenesis, the generation of new lymphatic vessels from preexisting ...
Kazuaki Takabe, Masayuki Nagahashi, Wei-Ching Huang, Krista P. Terracina   +3 more
doaj   +1 more source

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis.

, 2011
OBJECTIVE: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel biomarkers of morbidity and mortality in patients with severe sepsis. DESIGN: Multicenter longitudinal cohort study.
Hawkes, Michael, Michael Hawkes, Nimerta Rajwans, W. Conrad Liles, Fox-Robichaud, Alison, Lisa J. Toltl, Alison Fox-Robichaud, Patricia C. Liaw, Cook, Deborah J, Ricciuto, Daniel R, Lafferty, Erin I, Rajwans, Nimerta, Kain, Kevin C, Andrea L. Conroy, Kevin C. Kain, Conroy, Andrea L, Daniel R. Ricciuto, Deborah J. Cook, Kahnamoui, Kamyar, Erin I. Lafferty, dos Santos, Claudia C, Liaw, Patricia C, Liles, W Conrad, Kamyar Kahnamoui, Toltl, Lisa J, Claudia C. dos Santos   +25 more
core   +1 more source

Angiopoietin-2 and platelet-derived growth-BB factor cooperatively affect peripheral blood monocyte fibrinolysis [PDF]

, 2007
Includes bibliographical ...
Bezuidenhout, Louise
core   +1 more source