Results 21 to 30 of about 35,409 (231)

Update Overview of the Role of Angiopoietins in Lung Cancer

Medicina, 2021
Angiogenesis is a biological process that involves the formation of new blood vessels from the existing vasculature, and it plays a fundamental role in the development and progression of several types of cancer, including lung cancer.
Dimitris Tsakogiannis, Asimina Nikolakopoulou, Flora Zagouri, Grigorios Stratakos, Konstantinos Syrigos, Eleni Zografos, Nikolaos Koulouris, Garyfalia Bletsa   +7 more
doaj   +1 more source

Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance

Investigative Opthalmology & Visual Science, 2022
Defects in the iridocorneal angle tissues, including the trabecular meshwork (TM) and Schlemm's canal (SC), impair aqueous humor flow and increase the intraocular pressure (IOP), eventually resulting in glaucoma. Activation of endothelial tyrosine kinase receptor Tie2 by angiopoietin-1 (Angpt1) has been demonstrated to be essential for SC formation ...
Kapiainen, E. (Emmi), Elamaa, H. (Harri), Miinalainen, I. (Ilkka), Izzi, V. (Valerio), Eklund, L. (Lauri)   +4 more
openaire   +3 more sources

Serum Angiopoietin-1/Angiopoietin-2 at 16-18 Weeks of Gestation to Predict Preeclampsia

Journal of Health Science and Medical Research (JHSMR), 2021
Objective: To determine whether serum angiopoietin-1/angiopoietin-2 ratio can predict preeclampsia in women at 16–18 weeks of gestation, or not. Material and Methods: This was a prospective observational study that was conducted in pregnant women with ...
Vorapong Phupong, Patau Tanbirojn, Ruangsak Lertkhachonsuk   +2 more
doaj   +1 more source

Cellular and molecular aspects of diabetic nephropathy; the role of VEGF-A

Nefrología (English Edition), 2015
The prevalence of diabetes mellitus increased during the last century and it is estimated that 45% of the patients are not diagnosed. In South America the prevalence of diabetes and chronic kidney disease (CKD) increased, with a great disparity among the
Katherine Carranza, Dolores Veron, Alicia Cercado, Noemi Bautista, Wilson Pozo, Alda Tufro, Delma Veron   +6 more
doaj   +1 more source

Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

Journal of Lipid Research, 2019
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a widespread recognition of adipose tissue as an endocrine organ.
Jan-Bernd Funcke, Philipp E. Scherer
doaj   +1 more source

Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis

Biomolecules, 2013
The main function of the lymphatic system is to control and maintain fluid homeostasis, lipid transport, and immune cell trafficking. In recent years, the pathological roles of lymphangiogenesis, the generation of new lymphatic vessels from preexisting ...
Kazuaki Takabe, Masayuki Nagahashi, Wei-Ching Huang, Krista P. Terracina   +3 more
doaj   +1 more source

Prognostic value of circulatory growth factors to predict responsiveness to chemotherapy and remission status of patients with acute myeloid leukemia

Archives of Medical Science
Introduction Tumor neovascularization, an essential requirement for malignant disease progression and metastasis, depends on the dysregulation of pro-angiogenic and anti-angiogenic activities.
Mohammad Ahmad Bani-Ahmad, Duaa Ghanem
doaj   +1 more source

The role of proangiogenic cytokines in predicting sepsis in febrile neutropenic children with cancer

The Turkish Journal of Pediatrics
Background. We assessed the relationship between sepsis occurrence and the serum levels of angiopoietin (Ang-1, Ang-2), vascular endothelial growth factor (VEGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) in pediatric patients with cancer-related ...
Selma Çakmakcı, Neriman Sarı, Çiğdem Sönmez, İnci Ergürhan İlhan   +3 more
doaj   +1 more source

Association of Ang/Tie2 pathway mediators with endothelial barrier integrity and disease severity in COVID-19

Frontiers in Physiology, 2023
Endothelial barrier (EB) disruption contributes to acute lung injury in COVID-19, and levels of both VEGF-A and Ang-2, which are mediators of EB integrity, have been associated with COVID-19 severity.
Carla Roberta Peachazepi Moraes, Ivanio Teixeira Borba-Junior, Franciele De Lima, Jéssica Ribeiro Alves Silva, Bruna Bombassaro, André C. Palma, Eli Mansour, Lício Augusto Velloso, Lício Augusto Velloso, Fernanda Andrade Orsi, Fábio Trindade Maranhão Costa, Erich Vinicius De Paula, Erich Vinicius De Paula   +12 more
doaj   +1 more source

Normalization of the serum angiopoietin-1 to angiopoietin-2 ratio reflects response in refractory/resistant multiple myeloma patients treated with bortezomib

Haematologica, 2008
Neoangiogenesis is involved in the pathophysiology of multiple myeloma and angiopoietins possibly contribute to myeloma-induced neovascularization. Bortezomib’s antineoplastic potential includes an anti-angiogenic effect.
Konstantinos Anargyrou, Evangelos Terpos, Theodoros P. Vassilakopoulos, Anastasia Pouli, Sotirios Sachanas, Tatiana Tzenou, Stavroula Masouridis, Dimitrios Christoulas, Maria K. Angelopoulou, Evangelia M. Dimitriadou, Christina Kalpadakis, Konstantinos Tsionos, Panayiotis Panayiotidis, Meletios A. Dimopoulos, Gerassimos A. Pangalis, Marie-Christine Kyrtsonis   +15 more
doaj   +1 more source