Results 11 to 20 of about 35,409 (231)

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Biological characterization of angiopoietin‐3 and angiopoietin‐4

The FASEB Journal, 2004
ABSTRACT The angiopoietin (Ang) family of growth factors includes Ang1, Ang2, Ang3, and Ang4, all of which bind to the endothelial receptor tyrosine kinase Tie2. Ang3 (mouse) and Ang4 (human) are interspecies orthologs.
Lee, HJ, Cho, CH, Hwang, SJ, Choi, HH, Kim, KT, Ahn, SY, Kim, JH, Oh, JL, Lee, GM Lee, Gyun-Min, Koh, GY Koh, Gou Young   +9 more
  +8 more sources

Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors [PDF]

, 2017
Tumor blood vessel formation (angiogenesis) is essential for tumor growth and metastasis. Two main endothelial ligand–receptor pathways regulating angiogenesis are vascular endothelial growth factor (VEGF) receptor and angiopoietin-TIE receptor pathways.
Kiss, Elina A., Saharinen, Pipsa
openaire   +1 more source

Angiopoietin-1/Angiopoietin-2 Ratio for Prediction of Preeclampsia [PDF]

American Journal of Hypertension, 2009
A number of different biophysical and biochemical markers have been proposed as predictors of preeclampsia. Factors involved in the angiogenic balance are suggested as candidate markers. The purpose of this prospective, longitudinal cohort study was to determine whether a ratio between Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) can be used to ...
Marie, Bolin, Eva, Wiberg-Itzel, Anna-Karin, Wikström, Margareta, Goop, Anders, Larsson, Matts, Olovsson, Helena, Akerud   +6 more
openaire   +2 more sources

Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2

EMBO Molecular Medicine, 2015
Angiopoietin‐1 (Ang1) activation of Tie2 receptors on endothelial cells (ECs) reduces adhesion by tumor cells (TCs) and limits junctional permeability to TC diapedesis. We hypothesized that systemic therapy with Vasculotide (VT)—a purported Ang1 mimetic,
Florence TH Wu, Christina R Lee, Elena Bogdanovic, Aaron Prodeus, Jean Gariépy, Robert S Kerbel   +5 more
doaj   +1 more source

Serum Angiopoietin-1 and -2 and VEGF are associated with severe disease in vivax malaria

Journal of Vector Borne Diseases, 2020
Background & objectives: Malaria continues to be a significant public health problem in tropical countries including India; however, there are limited tools to predict occurrence of severe disease due to malaria.
Srinivas H Gowda, Hiren Anghan, Hridesh Mishra, Kunzang Chosdol, Manasvini Bhatt, Vinod Kumar, Piyush Ranjan, Praveen Aggarwal, Naveet Wig, Manish Soneja   +9 more
doaj   +1 more source

Angiogenesis, Lymphangiogenesis, and Inflammation in Chronic Obstructive Pulmonary Disease (COPD): Few Certainties and Many Outstanding Questions

Cells, 2022
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation, predominantly affecting the lung parenchyma and peripheral airways, that results in progressive and irreversible airflow obstruction.
Remo Poto, Stefania Loffredo, Francesco Palestra, Gianni Marone, Vincenzo Patella, Gilda Varricchi   +5 more
doaj   +1 more source

Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy

Frontiers in Cell and Developmental Biology, 2020
Diabetic retinopathy (DR) is a frequent diabetes-associated complication. Pericyte dropout can cause increased vascular permeability and contribute to vascular occlusion.
Heiner Kremer, Heiner Kremer, Julian Gebauer, Julian Gebauer, Susanne Elvers-Hornung, Susanne Elvers-Hornung, Stefanie Uhlig, Stefanie Uhlig, Stefanie Uhlig, Hans-Peter Hammes, Elena Beltramo, Lothar Steeb, Martin C. Harmsen, Carsten Sticht, Harald Klueter, Harald Klueter, Harald Klueter, Karen Bieback, Karen Bieback, Karen Bieback, Karen Bieback, Karen Bieback, Agnese Fiori, Agnese Fiori, Agnese Fiori   +24 more
doaj   +1 more source

Alteration of Angiogenic Gene Expression in Heart, Muscle and Adipose Tissue by Exercise [PDF]

운동과학, 2018
PURPOSE Exercise is one of the strongest stimuli for the induction of angiogenesis that is defined as a formation of new blood vessel. However, underlying mechanism of exercise-induced angiogenesis is not fully uncovered.
Hyuek Jong Lee
doaj   +1 more source

Serum angiopoietin-2 as a noninvasive diagnostic marker of stages of liver fibrosis in chronic hepatitis C patients

The Egyptian Journal of Internal Medicine, 2016
Background The process of fibrogenesis is associated with the development of disease-specific markers. The management of chronic hepatitis C (CHC) depends on the staging of liver fibrosis. Use of noninvasive methods is preferable in diagnosis and follow-
Mohamed M Makhlouf, Mahmoud A Osman, Shereen A.B. Saleh, Wael A Yousry, Mohamed L Soliman, Wahid H Doss, Fayrouz S Wahba   +6 more
doaj   +1 more source