Results 161 to 170 of about 57,083 (310)
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic +3 more
wiley +1 more source
Peripheral capillaries are damaged, and Raynaud’s phenomenon occurs frequently in patients with systemic sclerosis (SSc). Treatment with vasodilators often results in adverse effects, such as headache and facial flushing, and does not lead to sufficient ...
Yoshihito Shima, Akane Watanabe
doaj +1 more source
Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello +3 more
wiley +1 more source
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.
F. Arai +8 more
semanticscholar +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Overexpression of Angiopoietin-1 Reduces Doxorubicin-Induced Apoptosis in Cardiomyocytes
Doxorubicin (Dox) is a major anticancer chemotherapeutic agent. However, it causes cardiomyopathy due to the side effect of cardiomyocyte apoptosis.
Ha, Tuanzhu +5 more
core +1 more source
Understanding exosomes in diabetic wound healing
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Periodontitis and metabolic dysfunction‐associated steatotic liver disease
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon +6 more
wiley +1 more source
Inosculation potential of angiopoietin-4-immobilized pHEMA-based bone scaffolds
Although angiopoietin-1has potential therapeutic use in angiogenesis, the biological role of angiopoietin-4, especially in its immobilized form, is already unknown. In this study, vascularization potential of angiopoietin-4 either alone or in combination
Yurtsever, Merve Capkin +3 more
core +1 more source
Aim. To study the urinary excretion of the molecular factors regulating angiogenesis, such as vascular endothelial growth factor type A (VEGF-A), thrombospondin 1 (THBS1), and angiopoietin 2 (ANGPT2), versus that of the urinary markers of renal injury ...
M Yu Shvetsov +5 more
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