Results 121 to 130 of about 303,460 (358)
Arthritis &Rheumatology, EarlyView.Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato +9 more
wiley +1 more source
RAMIPRIL IN THERAPY OF PATIENTS AFTER MYOCARDIAL INFARCTION
Рациональная фармакотерапия в кардиологии, 2015 Angiotensin converting enzyme inhibitors are the first line medicine for the treatment of the most of cardiovascular diseases. There is no class-effect for these drugs in myocardial infarction therapy.
I. V. Szirov, E. V. Malichenko
doaj +3 more sources
The Application of Clinical Genetics, 2019 Mohanad Yasir Al-Radeef,1 Hayder Adnan Fawzi,2 Ali Abdulmajid Allawi31Department of Clinical Pharmacy, College of Pharmacy, Tikrit University, Tikrit, Iraq; 2Department of Clinical Pharmacy, Baghdad Medical City Hospital, Baghdad, Iraq; 3Department of ...
Al-Radeef MY, Fawzi HA, Allawi AA
doaj
Frontiers in Physiology, 2014 Hypertension is a major risk factor for stroke, coronary events, heart and renal failure, and the renin-angiotensin system (RAS) plays a major role in its pathogenesis.
Sheila K Patel +7 more
doaj +1 more source
Reduced cortical renal GLUT1 expression induced by angiotensin-converting enzyme inhibition in diabetic spontaneously hypertensive rats [PDF]
, 2008 Diabetes in spontaneously hypertensive rats is associated with cortical renal GLUT1 and GLUT2 overexpression. Our objective was to evaluate the effect of the angiotensin-converting enzyme blockade on cortical renal GLUT1 and GLUT2 expression, urinary ...
AZAMBUJA, F. +8 more
core +2 more sources
Angiotensin Converting Enzymes
, 2016 Angiotensin converting enzyme (ACE) is well known for its dual actions in converting inactive Ang I to active Ang II and degrade active bradykinin (BK), which play an important role in the control of blood pressure. Since the bottle neck step is the production of pressor Ang II, this was targeted pharmacologically in 1970s and successful ACE inhibitors
openaire +1 more source
Identification of functionally related enzymes by learning-to-rank methods [PDF]
arXiv, 2014 Enzyme sequences and structures are routinely used in the biological sciences as queries to search for functionally related enzymes in online databases. To this end, one usually departs from some notion of similarity, comparing two enzymes by looking for correspondences in their sequences, structures or surfaces. For a given query, the search operation
arxiv
Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Pediatric Patients with Mid to Severe Aortic Valve Regurgitation [PDF]
, 2018 The long-term benefit of angiotensin-converting enzyme inhibitors in pediatric patients with aortic valve regurgitation is under consideration.
Bauersfeld, Urs +3 more
core
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]
, 2016 Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H. +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet +6 more
wiley +1 more source