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Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of ...
D. Batlle+2 more
semanticscholar +1 more source
A new angiotensin-converting enzyme inhibitor from Peperomia pellucida (L.) Kunth
Objective: To isolate, identify, and evaluate a new angiotensin-converting enzyme inhibitor from Peperomia pellucida (L.) Kunth herbs. Methods: A dried sample of Peperomia pellucida herb was successively macerated with n-hexane and ethyl acetate.
Islamudin Ahmad+7 more
doaj +1 more source
Background An angiotensin‐converting enzyme (ACE) gene polymorphism occurs in dogs; however, functional importance is not well studied. Hypothesis We hypothesized that dogs with the polymorphism would show alternative renin‐angiotensin aldosterone system
Darcy Adin+7 more
doaj +1 more source
Angiotensin converting enzyme (ACE) is well known for its dual actions to convert inactive Ang I to active Ang II, and degrades active bradykinin (BK), which plays an important role in controlling blood pressure. Because it is the bottleneck step for the production of pressor Ang II, it was targeted pharmacologically in the 1970s.
openaire +1 more source
Angiotensin-Converting Enzyme Inhibitors [PDF]
Abstract—ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive, and hypertrophic properties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin and alter the metabolism of a number of other ...
Douglas E. Vaughan, Nancy J. Brown
openaire +2 more sources
Angiotensin II and COVID-19. Secrets of interactions
The article describes current data on the relationship of renin-angiotensin system and related drugs with the risk of COVID-19 infection and its outcomes.
A. O. Konradi, A. O. Nedoshivin
doaj +1 more source
The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S.+4 more
core +4 more sources
This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms. ACE2 is a crucial component of the renin‐angiotensin system (RAS).
Hao Cheng, Yan Wang, gui-qiang Wang
semanticscholar +1 more source
Serum angiotensin converting enzyme in pemphigus vulgaris
Background: Pemphigus vulgaris is an autoimmune blistering skin disease with unknown etiology. Drugs such as angiotensin-converting enzyme (ACE) inhibitors may contribute in the pathogenesis of pemphigus.
Reza M Robati+3 more
doaj +1 more source
Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita+123 more
core +1 more source