Results 41 to 50 of about 303,460 (358)

ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice

open access: yesClinics, 2018
OBJECTIVES: The present study aimed to investigate cardiovascular autonomic modulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene ...
Oscar Albuquerque de Moraes   +9 more
doaj   +1 more source

Direct Single Molecule Imaging of Enhanced Enzyme Diffusion [PDF]

open access: yesPhys. Rev. Lett. 123, 128101 (2019), 2018
Recent experimental results have shown that active enzymes can diffuse faster when they are in the presence of their substrates. Fluorescence correlation spectroscopy (FCS), which relies on analyzing the fluctuations in fluorescence intensity signal to measure the diffusion coefficient of particles, has typically been employed in most of the prior ...
arxiv   +1 more source

ACE inhibitor‐associated intestinal angioedema in orthotopic heart transplantation [PDF]

open access: yes, 2017
Angiotensin‐converting enzyme inhibitor induced angioedema commonly involves the head and neck area. We report a case of angiotensin‐converting enzyme inhibitor induced intestinal angioedema in a heart transplant recipient on mTOR immunosuppression. A 36‐
Byrd   +8 more
core   +1 more source

Controversy of angiotensin receptor blockers (ARBs) and angiotensin converting enzymeinhibitors (ACEIs) prescription for hypertension patients in coronavirus disease 2019 (COVID-19) pandemic [PDF]

open access: yes, 2020
Coronavirus disease 2019 (COVID-19) pandemic has made all the world in a mess. Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 infects human cells through angiotensin-converting enzyme 2 receptors (ACE receptors ...
Yuliana, Yuliana
core   +1 more source

Angiotensin-converting enzyme and male fertility [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
The angiotensin-converting enzyme (ACE; EC3.4.15.1) gene (Ace) encodes both a somatic isozyme found in blood and several other tissues, including the epididymis, and a testis-specific isozyme (testis ACE) found only in developing spermatids and mature sperm.
Oliver Smithies   +8 more
openaire   +3 more sources

Predictors and morphological properties of culprit healed plaques in patients with angina pectoris

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1199-1210, December 2022., 2022
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao   +5 more
wiley   +1 more source

Master curve of boosted diffusion for ten catalytic enzymes [PDF]

open access: yes, 2020
Molecular agitation more rapid than thermal Brownian motion is reported for cellular environments, motor proteins, synthetic molecular motors, enzymes, and common chemical reactions, yet that chemical activity couples to molecular motion contrasts with generations of accumulated knowledge about diffusion at equilibrium. To test the limits of this idea,
arxiv   +1 more source

The effect of chronic peripheral nesfatin-1 application on blood pressure in normal and chronic restraint stressed rats: Related with circulating level of blood pressure regulators [PDF]

open access: yes, 2015
Nesfatin is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is involved in the regulation of homeostasis. Although the effects of nesfatin-1 on nutrition have been studied widely in the literature, the mechanisms of ...
Ayada, C.   +3 more
core   +1 more source

Adherence with cardiovascular medications and the outcomes in patients with coronary arterial disease: “Real‐world” evidence

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1220-1228, December 2022., 2022
Abstract Background Cardiovascular medications are vital for the secondary prevention of coronary arterial disease (CAD). However, the effect of cardiovascular medication may depend on the optimal adherence of the patients. This meta‐analysis aims to determine the magnitude of adherence to vascular medications that influences the absolute and relative ...
Chen Chen   +5 more
wiley   +1 more source

Next Step in Chronic Kidney Disease Therapy

open access: yesPočki, 2016
Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous ...
D.D. Ivanov
doaj   +1 more source

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