Results 41 to 50 of about 1,135,948 (149)

Mobola plum seed methanolic extracts exhibit mixed type inhibition of angiotensin Ⅰ-converting enzyme in vitro

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To explore the possible inhibitory potentials and mechanism by Mobola plum (Parinari curatellifolia) seeds crude methanol (CE) and flavonoid-rich (FE) extracts on angiotensin-1-converting enzyme (ACE Ⅰ).
Olamide Olajusi Crown, Olanrewaju Sam Olayeriju, Ayodele Oluwaseyi Kolawole, Afolabi Clement Akinmoladun, Mary Tolulope Olaleye, Afolabi Akintunde Akindahunsi   +5 more
doaj   +1 more source

Study of the ACE Inhibitory Effect of Medicinal Plants Used in Iranian Folk-Medicine as Antihypertensive Remedy

Journal of Medicinal Plants, 2006
Background: Angiotensin converting enzyme (ACE) is an exopeptidase which converts angiotensin I to angiotensin II. Angiotensin II causes vasoconstriction and aldosteron secretion and inactivate bradykinin, so ACE has major role on blood pressure ...
SA Ziai, Sh Rezazadeh, A Dastpak, A Shabestari, M Taghizadeh, HA Naghdibadi, L Poorhoseini   +6 more
doaj  

Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis

Neural Plasticity, 2020
Electroacupuncture (EA) can effectively alleviate anxiety disorders and memory impairments caused by various neurodegenerative diseases; however, the molecular mechanisms underlying its neuroprotective effects are unclear.
Peipei Feng, Zemin Wu, Hao Liu, Yafang Shen, Xu Yao, Xinwei Li, Zui Shen   +6 more
doaj   +1 more source

Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS). [PDF]

, 2008
Current literature suggests that ACE SNP rs4343, ACE 2350A>G in exon 17, T202T, may be the best proxy for the ACE Alu I/D whereas rs4363 and rs4362 may be slightly stronger predictors of ACE levels. Considering reported difficulties in genotyping ACE I/D
Day, Ian N M, Rodriguez, Santiago, Gaunt, Tom R, Gaunt, TR, Huang, S, Lawlor, D, Guthrie, Philip Alexander Isles, Smith, George Davey, Abdollahi, Mohammad Reza, Lawlor, Debbie A, Abdollahi, MR, Ebrahim, S, Guthrie, PAI, Huang, Shuwen, Rodríguez, S, Day, INM, Day, Ian NM, Davey Smith, G, Ebrahim, Shah   +18 more
core   +1 more source

ACE insertion/deletion (I/D) polymorphism and diabetic nephropathy [PDF]

Journal of Nephropathology, 2012
Context: Angiotensin converting enzyme (ACE) gene encodes ACE, a key component of renin angiotensin system (RAS), plays an important role in blood pressure homeostasis by generating the vasoconstrictor peptide angiotensin II.
Zohreh Rahimi
doaj   +1 more source

Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial [PDF]

, 2014
<br>Background: Loss of muscle mass and strength with ageing is a major cause for falls, disability, and morbidity in older people. Previous studies have found that angiotensin-converting enzyme inhibitors (ACEi) may improve physical function in ...
Sumukadas, Deepa, Cvoro, Vera, McMurdo, Marion, Lloyd, Suzanne M., Band, Margaret, Miller, Suzanne, Witham, Miles, Struthers, Allan, McConnachie, Alex   +8 more
core   +1 more source

Mechanism & inhibition kinetics of bioassay-guided fractions of Indian medicinal plants and foods as ACE inhibitors

Journal of Traditional and Complementary Medicine, 2019
Hypertension is a becoming a major threat to the world. Angiotensin converting enzyme (ACE) is a key part in the renin angiotensin aldosterone system (RAAS) which control blood pressure.
Mohammad Yaseen Khan, Vimal Kumar
doaj   +1 more source

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with COVID-19: General Considerations and Clinical Implications

Journal of Cardiac Arrhythmias, 2020
Initially reported in China at the end of 2019, the coronavirus pandemic has now reached an international scale with more than1.5 million cases worldwide and more than 80,000 deaths by April 8th of this year.
Neiberg de Alcantara Lima, Pedro Yuri Paiva Lima, Ricardo Lessa de Castro Junior, Eric Martin Sieloff, Stela Maria Vitorino Sampaio   +4 more
doaj   +1 more source

Luteolin restores the renin-angiotensin system to alleviate blood pressure and cardiac changes in secondary hypertensive rats

Journal of Functional Foods
This study evaluates the effects of luteolin, a natural flavonoid, and its possible mechanisms on hypertension, cardiac dysfunction, and remodeling in rats with secondary hypertension.
Sudarat Rongpan, Piman Pocasap, Metee Iampanichakul, Terdthai Tong-Un, Putcharawipa Maneesai, Picha Kittipreeya, Parichat Prachaney, Poungrat Pakdeechote   +7 more
doaj   +1 more source

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس, پناهپور, حمداله   +1 more
core   +1 more source