Results 81 to 90 of about 636,232 (298)
Children With Short Stature Display Reduced ACE2 Expression in Peripheral Blood Mononuclear Cells
Frontiers in Endocrinology, 2022 BackgroundThe cause of short stature remains often unknown. The renin-angiotensin system contributes to growth regulation. Several groups reported that angiotensin-converting enzyme 2 (ACE2)-knockout mice weighed less than controls.
Federica Tonon +10 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Hepatic Mitochondrial Renin-Angiotensin Systems [PDF]
, 2015 Introduction: The circulating renin-angiotensin system (RAS) was originally described as a key endocrine regulator of intravascular homeostasis; however, the existence of a local (tissue) RAS has become increasingly reported in a variety of tissues ...
Skipworth, JRA
core
Frontiers in Pharmacology, 2014 Over the last decade an increasing number of studies have focused on the ability of G protein-coupled receptors to form heteromers and explored how receptor heteromerization modulates the binding, signaling and trafficking properties of individual ...
Ivone eGomes +3 more
doaj +1 more source
Angiotensin-converting enzyme 2 protects from severe acute lung failure
Nature, 2005 Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a devastating clinical syndrome with a high mortality rate (30–60%) (refs 1–3). Predisposing factors for ARDS are diverse and include sepsis, aspiration, pneumonias
Y. Imai +17 more
semanticscholar +1 more source
Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic
Nature Reviews Nephrology, 2020 The current COVID-19 pandemic is associated with unprecedented morbidity and mortality. Early reports suggested an association between disease severity and hypertension but did not account for sources of confounding. However, the responsible virus — SARS-
A. South +4 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source
Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]
, 2005 Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
core +1 more source
The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
Physiological Reviews, 2017 The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular system and hydroelectrolyte balance, with an influence on organs and functions throughout the body.
R. Santos +6 more
semanticscholar +1 more source
Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?
Journal of Hypertension, 2020 DOI:10.1097/HJH.0000000000002450 T he novel coronavirus causing the COVID-19 pandemic, SARS-CoV-2, gains entry to pulmonary cells after binding to membrane ACE2 [1].
M. Esler, D. Esler
semanticscholar +1 more source