Results 61 to 70 of about 636,232 (298)

Osmotic Adaptation by Na⁺-Dependent Transporters and ACE2: Correlation with Hemostatic Crisis in COVID-19

Biomedicines, 2020
COVID-19 symptoms, including hypokalemia, hypoalbuminemia, ageusia, neurological dysfunctions, D-dimer production, and multi-organ microthrombosis reach beyond effects attributed to impaired angiotensin-converting enzyme 2 (ACE2) signaling and elevated ...
Danah Muhanna, Shanvanth R. Arnipalli, Shashi B. Kumar, Ouliana Ziouzenkova   +3 more
doaj   +1 more source

Angiotensin-Converting Enzyme 2 (ACE2) in the Context of Respiratory Diseases and Its Importance in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

Pharmaceuticals, 2021
Angiotensin-Converting Enzyme 2 (ACE2) is an 805 amino acid protein encoded by the ACE2 gene expressed in various human cells, especially in those located in the epithelia. The primary function of ACE2 is to produce angiotensin (1–7) from angiotensin II (
Enrique Ambrocio-Ortiz, Gloria Pérez-Rubio, Alma D. Del Ángel-Pablo, Ivette Buendía-Roldán, Leslie Chávez-Galán, Rafael de Jesús Hernández-Zenteno, Alejandra Ramírez-Venegas, Jorge Rojas-Serrano, Mayra Mejía, Rogelio Pérez-Padilla, Cristóbal Guadarrama-Pérez, Ramcés Falfán-Valencia   +11 more
doaj   +1 more source

Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome

Endocrine Connections
Background: Arterial hypertension and left ventricular hypertrophy and remodeling are independent cardiovascular risk factors in patients with Cushing’s syndrome. Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be
Peter Wolf, Simon Travers, Oliver Domenig, Stephanie Baron, Anne Blanchard, Khaoula Bouazizi, Nadjia Kachenoura, Sylvie Salenave, Marko Poglitsch, Alban Redheuil, Severine Trabado, Jacques Young, Philippe Chanson, Peter Kamenický   +13 more
doaj   +1 more source

Angiotensin II-Induced Cardiovascular Fibrosis Is Attenuated by NO-Sensitive Guanylyl Cyclase1

Cells, 2020
In the NO/cGMP signaling cascade, relevant in the cardiovascular system, two NO-sensitive guanylyl cyclase (NO-GC) isoforms are responsible for NO-dependent cGMP generation.
Kathrin Broekmans, Jan Giesen, Lukas Menges, Doris Koesling, Michael Russwurm   +4 more
doaj   +1 more source

Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations

Frontiers in Endocrinology, 2021
BackgroundSomatic gene mutations that facilitate inappropriate intracellular calcium entrance have been identified in most aldosterone-producing adenomas (APAs).
Jung Soo Lim, Jung Soo Lim, Samuel W. Plaska, Juilee Rege, William E. Rainey, William E. Rainey, Adina F. Turcu   +6 more
doaj   +1 more source

Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]

, 2002
Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
Hausmann, Dirk, Koschyk, Dietmar H., Grip, Lars, Ferrari, Markus, de Jaegere, Peter, Rieber, Johannes, Figulla, Hans R., Mudra, Harald, Schächinger, Volker, Rothman, Martin, Voudris, Vassilis   +10 more
core   +1 more source

Angiotensin, vascular endothelial growth factor and caspase-3 levels in blood serum of smoking students [PDF]

The Ukrainian Biochemical Journal
Smoking cigarettes is currently considered a widespread behavioral habit among university students due to psychological, social, and behavioral factors.
I. A. A. K. Al-Samarai, A. J. Al Samer, H. N. Mohammed   +2 more
doaj   +1 more source

Treatment of hypertension with angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers and resting metabolic rate: A cross‐sectional study

The Journal of Clinical Hypertension, 2021
Hypertension in obese and overweight patients is associated with an elevated resting metabolic rate (RMR). The aim of this study was to determine whether RMR is reduced in hypertensive patients treated with angiotensin‐converting enzyme inhibitors (ACEI)
Pablo B. Pedrianes‐Martin, Marcos Martin‐Rincon, David Morales‐Alamo, Ismael Perez‐Suarez, Mario Perez‐Valera, Victor Galvan‐Alvarez, David Curtelin, Pedro dePablos‐Velasco, Jose A.L. Calbet   +8 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth? [PDF]

, 2005
Background Raised activity of the renin-angiotensin system (RAS) may both amplify inflammatory and free radical responses and decrease tissue metabolic efficiency and thus enhance cerebral injury in the preterm infant.
Montgomery, H, Harding, DR, Devadason David, Humphries, S, Whitelaw, A, David Davedason, Marlow Neil, Montgomery Hugh E, Marlow, N, Hugh E Montgomery, Davedason, D, Andrew Whitelaw, Humphries, SE, Neil Marlow, Montgomery, HE, Whitelaw Andrew, Humphries Steve E, Dhamrait Sukhbir, Devadason, D, Dhamrait, S, Steve E Humphries, Harding David R, David R Harding, Sukhbir Dhamrait   +23 more
core   +1 more source