Results 11 to 20 of about 25,584,253 (297)

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae. [PDF]

, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Isaac, R. Elwyn, Lee, Alison J., Smith, Judith A., Shirras, Alan D., Burnham, Susan   +4 more
core   +6 more sources

Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]

, 2002
Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E., Rumley, A., Lowe, G.D., Montgomery, H.E., Sanders, J., Brull, D.J.   +5 more
core   +8 more sources

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

Critical Care, 2020
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global pandemic.
W. Ni, Xiu-Wen Yang, Deqing Yang, J. Bao, Ran Li, Yong-Jiu Xiao, Chang-Jun Hou, Haibin Wang, Jie Liu, Donghong Yang, Yu Xu, Zhaolong Cao, Zhancheng Gao   +12 more
semanticscholar   +1 more source

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

Circulation Research, 2020
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory ...
M. Gheblawi, Kai-Ming Wang, A. Viveiros, Q. Nguyen, J. Zhong, A. Turner, M. Raizada, M. Grant, G. Oudit   +8 more
semanticscholar   +1 more source

Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice

Frontiers in Pharmacology, 2022
Angiotensin-converting enzyme 2 (ACE2) is the established cellular receptor for SARS-CoV-2. However, it is unclear whether ACE1 inhibitors (e.g., lisinopril) or angiotensin receptor blockers (e.g., losartan) alter tissue ACE2 expression.
Steven D. Brooks, Rachel L. Smith, Aline S. Moreira, Hans C. Ackerman   +3 more
doaj   +1 more source

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

Journal of Pathology, 2020
Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus responsible for the current devastating worldwide pandemic of coronavirus disease 2019
A. Bourgonje, A. Abdulle, W. Timens, J. Hillebrands, G. Navis, S. Gordijn, M. Bolling, Gerard Dijkstra, A. Voors, A. Osterhaus, P. V. D. van der Voort, D. Mulder, H. van Goor   +12 more
semanticscholar   +1 more source

Angiotensin Converting Enzyme 2 - at the Heart of the COVID-19 pandemic

Cell, 2023
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the COVID-19 pandemic, it has become one of the most therapeutically-targeted human molecules in biomedicine.
G. Oudit, Kai-Ming Wang, A. Viveiros, Max J. Kellner, J. Penninger   +4 more
semanticscholar   +1 more source

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.

Journal of the American Medical Association (JAMA), 2020
This study compares angiotensin-converting enzyme 2 (ACE2) gene expression, which has been associated with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.
S. Bunyavanich, Anh N. Do, A. Vicencio
semanticscholar   +1 more source

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Nature Medicine, 2005
During several months of 2003, a newly identified illness termed severe acute respiratory syndrome (SARS) spread rapidly through the world. A new coronavirus (SARS-CoV) was identified as the SARS pathogen, which triggered severe pneumonia and acute ...
K. Kuba, Y. Imai, Shuan Rao, Hong Gao, F. Guo, Bin Guan, Yi Huan, Peng-Fei Yang, Yan-Li Zhang, Wei Deng, L. Bao, Binlin Zhang, Guang Liu, Z. Wang, M. Chappell, Yanxin Liu, D. Zheng, A. Leibbrandt, T. Wada, Arthur S Slutsky, De-Pei Liu, C. Qin, Cheng-Yu Jiang, J. Penninger   +23 more
semanticscholar   +1 more source

Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19)

Journal of Clinical Medicine, 2020
The epicenter of the original outbreak in China has high male smoking rates of around 50%, and early reported death rates have an emphasis on older males, therefore the likelihood of smokers being overrepresented in fatalities is high.
S. Brake, K. Barnsley, Wen-Ying Lu, K. Mcalinden, M. Eapen, S. Sohal   +5 more
semanticscholar   +1 more source