Results 21 to 30 of about 25,584,253 (297)
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
Nature, 2003 Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells. Here we identify a metallopeptidase, angiotensin-converting
Wen-Hui Li +11 more
semanticscholar +1 more source
Journal of Medical Virology, 2020 This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms. ACE2 is a crucial component of the renin‐angiotensin system (RAS).
Hao Cheng, Yan Wang, Gui-Qiang Wang
semanticscholar +1 more source
Inverse association between hypertension treatment and COVID-19 prevalence in Japan
International Journal of Infectious Diseases, 2021 Objectives: Cell entry of SARS-CoV-2 depends on angiotensin-converting enzyme II. Angiotensin-converting enzyme II is homologous with, but acts antagonistically to, angiotensin-converting enzyme and has the critical function of protecting the lungs ...
Masako Kinoshita +4 more
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Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
Clinical science, 2020 A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of ...
D. Batlle, J. Wysocki, K. Satchell
semanticscholar +1 more source
Pathological Role of Angiotensin II in Severe COVID-19
TH Open, 2020 The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
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Angiotensin-converting enzyme 2 protects from severe acute lung failure
Nature, 2005 Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a devastating clinical syndrome with a high mortality rate (30–60%) (refs 1–3). Predisposing factors for ARDS are diverse and include sepsis, aspiration, pneumonias
Y. Imai +17 more
semanticscholar +1 more source
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
Cell, 2020 COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human angiotensin-converting enzyme 2 (hACE2) as the entry ...
Ren-di Jiang +19 more
semanticscholar +1 more source
Oftalʹmologiâ, 2020 Diabetic retinopathy (DR) is becoming more and more widespread disease. Investigation of local changes of metabolic pathways in the eye improves our knowledge about diabetic retinopathy pathogenesis and provide perspective for the development of new ...
V. V. Neroev +6 more
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Angiotensin converting enzyme 2 (ACE2) - the major receptor for SARS-CoV-2 virus [PDF]
Farmacja Polska, 2021 The renin-angiotensin-aldosterone system (RAS) plays a significant role in the regulation of the water and electrolyte balance. Renin from the kidneys converts angiotensinogen to angiotensin I. Angiotensin converting enzyme (ACE) catalyzes the conversion
Sonia Frankowska +3 more
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Progress of angiotensin converting enzyme 2 in cardiovascular diseases [PDF]
Jichu yixue yu linchuang, 2020 Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system.
JIAO Xiao-lu, QIN Yan-wen
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