Results 181 to 190 of about 5,061,790 (379)
Semiparametric Joint Modeling to Estimate the Treatment Effect on a Longitudinal Surrogate with Application to Chronic Kidney Disease Trials [PDF]
In clinical trials where long follow-up is required to measure the primary outcome of interest, there is substantial interest in using an accepted surrogate outcome that can be measured earlier in time or with less cost to estimate a treatment effect.
arxiv
Propensity scores using missingness pattern information: a practical guide [PDF]
Electronic health records are a valuable data source for investigating health-related questions, and propensity score analysis has become an increasingly popular approach to address confounding bias in such investigations. However, because electronic health records are typically routinely recorded as part of standard clinical care, there are often ...
arxiv
Differential involvement of hippocampal angiotensin 1 receptors in learning and memory processes in bulbectomized rats [PDF]
There is conflicting evidence regarding the effect of AT1 receptor antagonists on learning and memory processes. The effects of angiotensin II and losartan administration into CA1 hippocampal area on the avoidance performance in olfactory bulbectomized ...
Belcheva, Iren+3 more
core +1 more source
The radioimmunoassay of angiotensin II [PDF]
G. W. Boyd, J. Landon, W. S. Peart
openalex +1 more source
Background Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes and decreased nephrin production.
Rhea Bhargava+9 more
wiley +1 more source
Effect of rabbit antibodies against angiotensin‐II on the pressor response to angiotensin‐II and renal hypertension in the rat [PDF]
P. R. Hedwall
openalex +1 more source
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin+9 more
wiley +1 more source
Angiotensin II for the Treatment of Vasodilatory Shock
A. Khanna+32 more
semanticscholar +2 more sources
INCREASED SUSCEPTIBILITY TO PYELONEPHRITIS DURING ACUTE HYPERTENSION BY ANGIOTENSIN II AND NOREPINEPHRINE* [PDF]
R. K. Jones, Alvin P. Shapiro
openalex +1 more source
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia+4 more
wiley +1 more source