Results 81 to 90 of about 365,351 (311)
Advanced Science, EarlyView.NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song +12 more
wiley +1 more source
Journal of International Medical ResearchObjective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive function.
Yongli Han +7 more
doaj +1 more source
Особенности использования антигипертензивных препаратов у больных сахарным диабетом [PDF]
, 2004 In this article the modern data about pharmaceuticals drugs that used for treatment of patients with arterial hypertension and diabetes mellitus are submitted.
Rachynskyi, Ivan Danylovych +3 more
core
Advanced Science, EarlyView.This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
PLoS ONEThe renin-angiotensin system is known for its role in renal physiology by regulating renal hemodynamics and natriuresis. Overactivation of this system exerts pathological effects in the kidney, primarily mediated by its main effector peptide angiotensin ...
Debora Kaiser-Graf +4 more
doaj +1 more source
Preeclampsia, the Renin-Angiotensin-Aldosterone System and beyond [PDF]
, 2015 __Abstract__ The renin-angiotensin-aldosterone system (RAAS) plays an essential role in the regulation of blood pressure and body fluid homeostasis, but also contributes importantly to the pathophysiology of hypertension, renal disease and heart ...
Verdonk, K. (Koen)
core +1 more source
Angiotensin II and VEGF are Involved in Angiogenesis Induced by Short-Term Exercise Training [PDF]
, 2001 Results from our laboratory have suggested a pathway involving angiotensin II type 1 (AT1) receptors and vascular endothelial growth factor (VEGF) in angiogenesis induced by electrical stimulation.
Amaral, Sandra L. +2 more
core +2 more sources
The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity
AGING MEDICINE, EarlyView.Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley +1 more source
AGING MEDICINE, EarlyView.The AWGS 2025 consensus shifts focus from diagnosing sarcopenia to promoting muscle health across the lifespan. It simplifies diagnosis to low muscle mass plus low strength, expands screening to middle‐aged adults, and integrates muscle health into the WHO ICOPE framework for early intervention and healthy aging.
Bi Jianghan, Li Jiaojiao, Kang Lin
wiley +1 more source