Results 101 to 110 of about 6,209,552 (299)
Background Endothelial prolyl hydroxylase‐2 (PHD2) is essential for pulmonary remodeling and hypertension. In the present study, we investigated the role of endothelial PHD2 in angiotensin II–mediated arterial stiffness, pericyte recruitment, and cardiac
Bo Liu +6 more
doaj +1 more source
Roles and functions of Atp6ap2 in the brain
The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke +1 more
doaj +1 more source
Effect of renal denervation on Renin-Angiotensin-Aldosterone System (RAAS).
Plasma levels of rennin (A), angiotensin-II (B) and aldosterone (C) in the sham-operated, abdominal aortic constriction (AAC), abdominal aortic constriction with renal denervation (AAC-RD) groups.
Yong Wei (44544) +5 more
core +1 more source
Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
SARS-CoV-2 interacting with its receptor, angiotensin-converting enzyme 2 (ACE2), turns the host response to viral infection into a dysregulated uncontrolled inflammatory response. This is because ACE2 limits the production of the peptide angiotensin II (
Richard Head (2217217) +6 more
core
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
ANGIOTENSIN II AND MYOCARDIAL INFARCTION
The role of angiotensin II in pathogenesis of cardiovascular diseases is discussed. Angiotensin II participates in development of acute myocardial infarction (MI) in patients with atherosclerosis.
O. P. Shevchenko, А. О. Shevchenko
doaj +1 more source
Transepithelial projections from basal cells are luminal sensors in pseudostratified epithelia
Basal cells are by definition located on the basolateral side of several epithelia, and they have never been observed reaching the lumen. Using high-resolution 3D confocal imaging, we report that basal cells extend long and slender cytoplasmic ...
McKee, Mary +5 more
core +1 more source
Aim Temporal shifts in patient characteristics can influence comparative treatment effects within a certain indication. We investigated patient characteristics and comparative effectiveness and safety for direct oral anticoagulants (DOACs) and warfarin over the time period where DOACs replaced warfarin as preferred stroke prophylaxis in patients with ...
Raoul B. L. J. van den Hemel +6 more
wiley +1 more source
Effect of Angiotensin II on Blood Flow in Acute and Chronically Inflamed Knee Joints of Rabbits: The Role of Nitric Oxide [PDF]
Background: Angiotensin converting enzyme (ACE) upregulationin stromal cells of joints affected by rheumatoid arthritismay lead to higher tissue angiotensin II that is a vasoconstrictorand mitogen factor.
Hamid Najafipour +3 more
doaj

