Association is not causation: treatment effects cannot be estimated from observational data in heart failure [PDF]
, 2018 Aims: Treatment ‘effects’ are often inferred from non-randomized and observational studies. These studies have inherent biases and limitations, which may make therapeutic inferences based on their results unreliable.
Campbell, Ross T. +4 more
core +1 more source
Mitigation of Radiation Induced Pulmonary Vascular Injury by Delayed Treatment with Captopril [PDF]
, 2012 Background and Objective: A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary ...
Fish, Brian L. +5 more
core +2 more sources
The choice of combination antihypertensive therapy in patients with type 2 diabetes
Медицинский совет, 2015 The article tells about optimum choice of combination antihypertensive therapy in patients with diabetes mellitus 2. The article discusses the efficacy of combination therapy based on two types of RAAS blockade (angiotensin-converting enzyme inhibitor or
O. A. Koshelskaya +2 more
doaj +1 more source
Angiotensin II Inhibits Insulin Binding to Endothelial Cells [PDF]
Diabetes & Metabolism Journal, 2011 BackgroundInsulin-mediated glucose uptake in insulin target tissues is correlated with interstitial insulin concentration, rather than plasma insulin concentration.
Su-Jin Oh +8 more
doaj +1 more source
A novel mechanism of action for angiotensin-(1-7) via the angiotensin type 1 receptor [PDF]
, 2016 No abstract ...
Nicklin, Stuart A.
core +1 more source
Journal of Pharmacological Sciences, 2013 .: In the present study, we investigated the effects of angiotensin AT1–receptor blockers, KT3-671 and losartan, on the cardiac vagal neurotransmission in pithed rats.
Fumiko Yamaki +4 more
doaj +1 more source
Blood pressure control versus atrial fibrillation management in stroke prevention [PDF]
, 2015 Hypertension is one of the major risk factors for atrial fibrillation which in turn is the most prevalent concomitant condition in hypertensive patients. While both these pathological conditions are independent risk factors for stroke, the association of
Sada, Lidia +2 more
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BMC NeuroscienceBackground Astrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity.
Daniel Navin Olschewski +12 more
doaj +1 more source
Increased hazard of myocardial infarction with insulin‐provision therapy in actively smoking patients with diabetes mellitus and stable ischemic heart disease: The BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial [PDF]
, 2017 Background In the BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial, randomization of diabetic patients with stable ischemic heart disease to insulin provision ( IP
Brown, David L +3 more
core +2 more sources
Journal of Nobel Medical College, 2020 Background: Hypertension is leading cause of deaths in the world. It is a modifiable and major risk factor for cardiovascular, renal and brain diseases. This study was done to see the current trend of prescription patterns of antihypertensive drugs in a ...
Kamal Sharma Lamsal +2 more
doaj +1 more source