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Clinical Pharmacology of the Angiotensin Receptor Antagonists [PDF]

open access: yesThe Journal of Clinical Hypertension, 2001
JOURNAL OF CLINICAL HYPERTENSION 45 OVERVIEW Selective blockade of the angiotensin (AT1) receptor is a novel means by which the renin-angiotensin axis can be interrupted.
D. Sica
semanticscholar   +4 more sources

Pharmacotherapy Review: Angiotensin Receptor Antagonists

open access: yesThe Journal of Clinical Hypertension, 2005
Angiotensin receptor blockers are one of several drug classes that act by interfering with activity of the renin‐angiotensin axis. Drugs in this class are as effective as angiotensin‐converting enzyme inhibitors in the reduction of blood pressure in ...
D. Sica
semanticscholar   +5 more sources

Angiotensin II receptor antagonists for heart failure [PDF]

open access: bronzeHeart, 1998
ACE inhibitors have revolutionised the treatment of chronic heart failure; however, as is often the case with drug treatment, we are remarkably ignorant of exactly how they work. Understanding the mechanisms involved is of fundamental importance because it is a major goal of pharmacological research to produce more specific drugs that act on the ...
Allan D. Struthers
openalex   +6 more sources

Angiotensin-converting enzyme inhibitors, angiotensin-II-receptor antagonists and angiotensin-receptor blocker/neprilysin inhibitor utilization in heart failure patients: Sub-analysis of a nation-wide population-based study in the Czech Republic

open access: yesBiomedical Papers, 2022
Aims. Sub-analysis of a retrospective nation-wide observational analysis of heart failure (HF) epidemiology reported to the Czech National Registry of Reimbursed Health Services between 2012 and 2018 aimed at angiotensin-converting enzyme inhibitors ...
Renata Aiglova   +10 more
doaj   +1 more source

Angiotensin II receptor antagonists in hypertension [PDF]

open access: yesKidney International, 1998
Blockade of the renin-angiotensin system is now recognized as an effective approach to the treatment of hypertension and congestive heart failure. Today, it is possible to antagonize the effects of angiotensin II more specifically by blocking its receptors by using nonpeptide receptor antagonists.
Michel Burnier, Hans R. Brunner
openaire   +3 more sources

Difficult choice: angiotensin receptor antagonists

open access: yesРоссийский кардиологический журнал, 2013
The paper is focussed on the therapeutic choice of angiotensin receptor antagonists (ARA). The author presents the data on the comparison between different sartans and their benefits which are not explained by the blood pressure reduction.
E. O. Taratukhin
doaj   +1 more source

Synthetic nanobodies as angiotensin receptor blockers

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance The G protein-coupled receptor (GPCR) family is responsible for regulating much of human physiology, and GPCRs have become the most successful target class for drug development.
Conor McMahon   +9 more
semanticscholar   +1 more source

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