Results 1 to 10 of about 80,027 (384)

Angiotensin II receptor antagonists for heart failure [PDF]

open access: bronzeHeart, 1998
ACE inhibitors have revolutionised the treatment of chronic heart failure; however, as is often the case with drug treatment, we are remarkably ignorant of exactly how they work. Understanding the mechanisms involved is of fundamental importance because it is a major goal of pharmacological research to produce more specific drugs that act on the ...
Allan D. Struthers
openalex   +6 more sources

Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension? [PDF]

open access: yesVascular Health and Risk Management, 2007
Marc P Maillard, Michel BurnierService of Nephrology, Department of Internal Medicine, Lausanne University Hospital, SwitzerlandAbstract: Blockade of the renin-angiotensin system with selective AT1 receptor antagonists is recognized as an effective mean ...
Marc P Maillard, Michel Burnier
doaj   +2 more sources

Angiotensin-converting enzyme inhibitors, angiotensin-II-receptor antagonists and angiotensin-receptor blocker/neprilysin inhibitor utilization in heart failure patients: Sub-analysis of a nation-wide population-based study in the Czech Republic

open access: yesBiomedical Papers, 2022
Aims. Sub-analysis of a retrospective nation-wide observational analysis of heart failure (HF) epidemiology reported to the Czech National Registry of Reimbursed Health Services between 2012 and 2018 aimed at angiotensin-converting enzyme inhibitors ...
Renata Aiglova   +10 more
doaj   +1 more source

Angiotensin II receptor antagonists in hypertension [PDF]

open access: yesKidney International, 1998
Blockade of the renin-angiotensin system is now recognized as an effective approach to the treatment of hypertension and congestive heart failure. Today, it is possible to antagonize the effects of angiotensin II more specifically by blocking its receptors by using nonpeptide receptor antagonists.
Michel Burnier, Hans R. Brunner
openaire   +3 more sources

Difficult choice: angiotensin receptor antagonists

open access: yesРоссийский кардиологический журнал, 2013
The paper is focussed on the therapeutic choice of angiotensin receptor antagonists (ARA). The author presents the data on the comparison between different sartans and their benefits which are not explained by the blood pressure reduction.
E. O. Taratukhin
doaj   +1 more source

Historical overview, development and new approaches in design of angiotensin converting enzyme inhibitors and angiotensin receptor antagonists. Part I [PDF]

open access: yes, 2016
The renin-angiotensin system (RAS) plays an important role in pathogenesis of hypertension, congestive heart failure, and chronic renal failure. In addition to a discussion of the current understanding of the chemical structures and the modes of action ...
Drapak, Iryna   +3 more
core   +2 more sources

In-Silico evidence for two receptors based strategy of SARS-CoV-2 [PDF]

open access: yesFront. Mol. Biosci., 09 June 2021, 2020
We propose a novel numerical method able to determine efficiently and effectively the relationship of complementarity between portions of proteins surfaces. This innovative and general procedure, based on the representation of the molecular iso-electron density surface in terms of 2D Zernike polynomials, allows the rapid and quantitative assessment of ...
arxiv   +1 more source

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