Results 71 to 80 of about 450,783 (333)

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

Annals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale, Arkadiusz Nawrocki, Johanne J. Korsbæk, Nadja S. Hansen, Fabian Foettinger, Nik Krajnc, Mathias J. Norvig, Niclas L. Eriksen, Stefan Macher, Berthold Pemp, Connar S.J. Westgate, Christian B. Pedersen, Frantz R. Poulsen, Sune Munthe, Gabriel Bsteh, Martin R. Larsen, Rigmor H. Jensen, Dagmar Beier   +17 more
wiley   +1 more source

Metabolic syndrome and angiotensin II receptor antagonists

Кардиоваскулярная терапия и профилактика, 2007
Aim. To investigate the effects of angiotensin II receptor antagonist irbesartan on blood pressure (BP), tissue insulin sensitivity, carbohydrate and lipid metabolism, cerebral perfusion parameters in patients with arterial hypertension (AH), metabolic ...
K. M. Mamyrbayeva, V. B. Mychka, V. B. Sergienko, I. E. Chazova   +3 more
doaj  

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

The Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Emerging Benefits of AT1 Receptor Antagonists With Pleiotropic Anti-Inflammatory Activity

, 2011
In summary, angiotensin receptor antagonists with pleiotropic properties, such as telmisartan, have a great deal to recommend them in the treatment of the metabolic syndrome: they are antihypertensive, anti-inflammatory, may lower blood glucose ...
L. Brown, C. Sernia, Brown, Lindsay, Sernia, Conrad   +3 more
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

RENIN-ANGIOTENSIN PROFILE AND COMPARATIVE EFFECTIVENESS OF FIRST-LINE MEDICATIONS IN MONOTHERAPY OF ESSENTIAL ARTERIAL HYPERTENSION

Российский кардиологический журнал, 2010
The study investigated the rational antihypertensive therapy in 966 patients with essential arterial hypertension (AH) and various renin-angiotensin blood profiles.
Sh. V. Akhadov, G. R. Ruzbanova, G. S. Molchanova   +2 more
doaj  

Comparative Mortality in Heart Failure on Guideline‐Directed Medical Therapy Versus Malignant Cancer: A Report From a Global Federated Research Network

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Guideline‐directed medical therapy (GDMT), including angiotensin receptor‐neprilysin inhibitor, angiotensin‐converting enzyme inhibitors, beta blockers, mineralocorticoid receptor antagonists, and sodium‐glucose cotransporter‐2 inhibitors, has
Luca Monzo, Guillaume Baudry, Kevin Duarte, Gema Hernandez, Olivier Denquin, Gianluigi Savarese, Nicolas Girerd   +6 more
doaj   +1 more source

Hormone treatments in congestive heart failure

Journal of International Medical Research, 2018
The common ultimate pathological feature for all cardiovascular diseases, congestive heart failure (CHF), is now considered as one of the main public health burdens that is associated with grave implications. Neurohormonal systems play a critical role in
Lei Lei, Yuanjie Mao
doaj   +1 more source

Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells

Brazilian Journal of Medical and Biological Research, 2001
A construct (AT1R-NF) containing a "Flag" sequence added to the N-terminus of the rat AT1 receptor was stably expressed in Chinese hamster ovary cells and quantified in the cell membrane by confocal microscopy after reaction with a fluorescein-labeled ...
A.J. Merjan, C.A. Kanashiro, J.E. Krieger, S.W. Han, A.C.M. Paiva   +4 more
doaj   +1 more source

Angiotensin II type 1 receptor antagonists in the treatment of hypertension in elderly patients: focus on patient outcomes

, 2011
Artavazd Tadevosyan1, Eric J MacLaughlin2, Vardan T Karamyan31Departments of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, QC, Canada; 2Department of Pharmacy Practice, 3Department of Pharmaceutical ...
Eric J MacLaughlin, Artavazd Tadevosyan, Vardan T Karamyan   +2 more
core