Results 171 to 180 of about 86,631 (266)

Impact of Dapagliflozin on MRI‐Derived Epicardial Adipose Tissue: Secondary Imaging Analysis of a Randomized Trial

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium–glucose cotransporter‐2 (SGLT2) inhibitors reduce EAT thickness in patients with type 2 diabetes mellitus (T2DM). However, it is unclear whether this is
Min Jae Cha, Negar Firoozeh, Anna V. Naumova, Peter Muzi, Karen G. Ordovas, Dennis D. Wang, Daniel Isquith, Chuck Maynard, Xue‐Qiao Zhao, Francis Kim   +9 more
wiley   +1 more source

COVID-19 Pandemic Waves and 2024-2025 Winter Season in Relation to Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers and Amantadine. [PDF]

Healthcare (Basel)
Puigdellívol-Sánchez A, Juanes-González M, Calderón-Valdiviezo AI, Losa-Puig H, González-Salvador M, León-Pérez M, Pueyo-Antón L, Franco-Romero M, Lozano-Paz C, Cortés-Borra A, Valls-Foix R.   +10 more
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Reducing the Risk of Developing Diabetes: The Role of Angiotensin Receptor Blockers and Angiotensin Converting Enzyme Inhibitors in Patients With Hypertension Combined Prediabetes. [PDF]

J Clin Hypertens (Greenwich)
Yang C, Hu Z, Sa R, Li R, Li Y, Wu Y, Shi G, Qiu L, Li C.   +8 more
europepmc   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

Retrospective analysis of neoplasms in patients using angiotensin receptor blockers. [PDF]

Sci Rep
Sharma AK, Rastogi S, Goyal RK.
europepmc   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo, Shang‐Yong Feng, Hui Chen, Dun‐Min She, Yan Liu, Ying Li, Cai‐Feng Yan, Zhen‐Wen Zhang, Jing Chen, Xiao‐Li Cai, Gao‐Yu Zhao, Hui Yu, Yan Wang   +12 more
wiley   +1 more source

ACE Inhibitors and Angiotensin Receptor Blockers for the Prevention of Cardiovascular Outcomes: Recommendations from the 2024 Egyptian Cardiology Expert Consensus. [PDF]

Cardiol Ther
Poulter N.
europepmc   +1 more source

Comparative Effects of Angiotensin Receptor Blockers on Blood Pressure and Serum Urate in Patients With Hypertension and Hyperuricaemia: A Systematic Review and Network Meta‐Analysis

Medicine Bulletin, EarlyView.
Allisartan ranked best for serum urate reduction and showed favourable blood pressure control, whereas losartan also performed well overall. These rankings may inform ARB selection but should be interpreted cautiously because of inconsistency, heterogeneity and sparse direct evidence.
Xuanyao Li, Xinyi Wang, Xiaolei Ren, Yalin Wang, Hua Shao, Xueli Zhang   +5 more
wiley   +1 more source

Angiotensin receptor blockers use and lung cancer risk in Chinese patients with chronic obstructive pulmonary disease: a population-based cohort study. [PDF]

Respir Res
Li W, Yang Q, Chen Y, Sun Y, Shen P, Sun F, Jia J.   +6 more
europepmc   +1 more source