Results 191 to 200 of about 86,631 (266)

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Angiotensin Receptor Blockers for Hypertension and Risk of Epilepsy.

JAMA Neurol
Wen X, Otoo MN, Tang J, Brothers T, Ward KE, Asal N, Meador KJ.   +6 more
europepmc   +1 more source

Angiotensin Receptor Blockers and Cognition: a Scoping Review. [PDF]

Curr Hypertens Rep
Zhou Z, Orchard SG, Nelson MR, Fravel MA, Ernst ME.   +4 more
europepmc   +1 more source

YK‐4‐250, a synthetic telmisartan–tempol conjugate: crystal structure of a stabilized free radical containing an angiotensin AT1 receptor inhibitor

Acta Crystallographica Section C, EarlyView.
The first crystal structure of the telmisartan–tempol conjugate YK‐4‐250 is reported, revealing the intramolecular C–H…π interactions that stabilize the nitroxide radical while preserving the angiotensin AT1 receptor antagonist pharmacophore.We report the first crystal structure of the telmisartan–tempol conjugate 2,2,6,6‐tetramethyl‐1‐(λ′‐oxidaneyl ...
Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton   +4 more
wiley   +1 more source

Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Is Associated With a Reduced Risk of Poststroke Epilepsy in Patients With Ischemic Stroke. [PDF]

J Am Heart Assoc
Chang KC, Lin CH, Huang JA.
europepmc   +1 more source

Influencing Factors Associated With Infantile Hemangioma: A Case–Control Study Among Chinese Pediatric Populations

The Journal of Dermatology, EarlyView.
ABSTRACT Infantile hemangioma (IH) is the most common benign vascular tumor of infancy. While its epidemiology is well‐documented in Caucasian populations, large‐scale systematic studies regarding clinical characteristics and risk factors in the Chinese population remain limited.
Xinyu Liu, Dan Song, Liang Wang, Changfeng Wang, Lei Guo   +4 more
wiley   +1 more source

Case Report: Angiotensin converting enzyme inhibitors vs. angiotensin receptor blockers in the management of chronic hypertension: a case of lisinopril-induced rhinorrhea. [PDF]

Front Allergy
Amudzi AA, Samale GR, Vela-Parada X.
europepmc   +1 more source

Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time‐averaged cumulative systolic blood pressure (TACsBP‐inD) as a new metric

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 525-534, June 2025.
Abstract Background Blood pressure is a crucial risk factor for hemodialysis patients, but the specific impact of weather factors, particularly barometric pressure, on blood pressure remains unclear. This study aims to examine the relationship between barometric pressure and blood pressure in hemodialysis patients. Methods We conducted a single‐center,
Kosaku Iwatsubo, Shouichi Fujimoto, Michikazu Nakai   +2 more
wiley   +1 more source

Comparative Efficacy and Safety of Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Calcium Channel Blockers in Hypertensive Patients With Chronic Kidney Disease: A Systematic Review. [PDF]

Cureus
Mhmndar MA, Singh T, Fatima I, Shehryar A, Zaidi MR, Mairaj M, Khan SM, Kolanu ND, Ahmed S, Kamal A, Rehman A, Quinn M.   +11 more
europepmc   +1 more source

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source