Results 251 to 260 of about 180,674 (285)
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Angiotensin II Receptor Subtypes
American Journal of Hypertension, 1992The octapeptide, angiotensin II (Ang II), the biologically active component of the renin-angiotensin system, elicits its multiple actions through the stimulation of specific surface receptors on various target organs. Although the existence of Ang II receptor subtypes has been suspected for some time, definitive evidence for Ang II receptor ...
P B, Timmermans +4 more
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Angiotensin II receptor antagonists
The Lancet, 2000Blockade of the renin-angiotensin system began as a way of studying the pathogenesis of cardiovascular disease with specific pharmacological probes. Oral activity, achieved by shortening the original peptide structures, transformed the probes into therapeutic agents, the angiotensin-converting enzyme (ACE) inhibitors.
M, Burnier, H R, Brunner
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Angiotensin and angiotensin receptors in cartilaginous fishes
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2001In mammals, a principal bioactive component of the renin-angiotensin system (RAS), angiotensin II (ANG II), is known to be vasopressor, dipsogenic, a stimulant of adrenocortical secretion and to control glomerular and renal tubular function. Historically, a RAS analogous to that found in mammals was thought to have first evolved in the bony fishes ...
ANDERSON W. G +6 more
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Angiotensin receptor blockers and angiotensin receptor–neprilysin inhibitors
2022Abstract This chapter addresses angiotensin receptor blockers (ARBs) and angiotensin receptor–neprilysin inhibitors (ARNIs). ARBs or angiotensin II receptor antagonists were introduced as a potentially superior alternative to an angiotensin converting enzyme (ACE) inhibitor and, later, as a possible addition to an ACE inhibitor.
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Angiotensin II Receptor Assays
Current Protocols in Pharmacology, 1998AbstractThis unit describes the use of an isolated rabbit thoracic aorta preparation for determining the nature, potency, and selectivity of antagonists to the agonism of angiotensin II at AT1 receptors by measuring their effects on the tension of the tissue.
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2004
Although angiotensin IV (Ang IV) was thought initially to be an inactive product of angiotensin II (Ang II) degradation, the hexapeptide was subsequently shown to markedly enhance learning and memory in normal rodents and reverse memory deficits observed in animal models of amnesia. These central nervous system effects of Ang IV are mediated by binding
S. Y. Chai +5 more
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Although angiotensin IV (Ang IV) was thought initially to be an inactive product of angiotensin II (Ang II) degradation, the hexapeptide was subsequently shown to markedly enhance learning and memory in normal rodents and reverse memory deficits observed in animal models of amnesia. These central nervous system effects of Ang IV are mediated by binding
S. Y. Chai +5 more
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American Journal of Physiology-Legacy Content, 1970
S Y, Lin, T L, Goodfriend
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S Y, Lin, T L, Goodfriend
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1995
The renin-angiotensin system (RAS) profoundly influences cardiovascular function. The system likely evolved to meet the need to preserve cardiovascular function in response to stressors such as hemorrhage, dehydration and dietary sodium deficiency.
Robert C. Speth +2 more
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The renin-angiotensin system (RAS) profoundly influences cardiovascular function. The system likely evolved to meet the need to preserve cardiovascular function in response to stressors such as hemorrhage, dehydration and dietary sodium deficiency.
Robert C. Speth +2 more
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International Journal of Biochemistry, 1992
R, Seyer, J P, Richoux, A, Aumelas
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R, Seyer, J P, Richoux, A, Aumelas
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