Results 61 to 70 of about 21,917 (243)

Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function

Clinical Cardiology, Volume 45, Issue 12, Page 1287-1296, December 2022., 2022
Abstract Background Type 2 diabetes mellitus (T2DM) patients may have cardiac remodeling and dysfunction from the early stage of disease. This study aimed to determine the association between cystatin C (CysC) and early cardiac functional or structural impairment in T2DM patients without renal dysfunction.
Zhuoshan Huang, Junlin Zhong, Shaozhao Zhang, Zhenyu Xiong, Yiquan Huang, Menghui Liu, Yifen Lin, Xiangbin Zhong, Xiaomin Ye, Xiaodong Zhuang, Xinxue Liao   +10 more
wiley   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Predicting progression of aortic stenosis by measuring serum calcification propensity

Clinical Cardiology, Volume 45, Issue 12, Page 1297-1302, December 2022., 2022
Abstract Background The aim of this prospective, double‐blinded study in patients with aortic sclerosis was to determine whether a new calcification propensity measure in the serum could predict disease progression. Methods We included 129 consecutive patients with aortic sclerosis as assessed during a routine clinical echocardiographic exam. Clinical,
Reto Kurmann, Eric Buffle, Andreas Pasch, Christian Seiler, Stefano F. de Marchi   +4 more
wiley   +1 more source

Structural analysis of SARS-CoV-2 and prediction of the human interactome [PDF]

arXiv, 2020
Specific elements of viral genomes regulate interactions within host cells. Here, we calculated the secondary structure content of >2500 coronaviruses and computed >100000 human protein interactions with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
arxiv  

A case of widespread unilateral subcutaneous sarcoidosis with ocular and pulmonary involvements with seropositivity for anti‐double strand‐DNA antibody and rheumatoid factor: A revisit of gap between humoral autoimmune abnormalities and clinical findings

, 2022
Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 227-228, December 2022.
Noritaka Oyama, Natsuki Baba, Hideki Ido, Minoru Hasegawa   +3 more
wiley   +1 more source

Prevalence, clinical characteristics, and predictors of sleep disordered breathing in hospitalized heart failure patients

Clinical Cardiology, Volume 45, Issue 12, Page 1311-1318, December 2022., 2022
Abstract Background Heart failure (HF) is often comorbid with sleep disordered breathing (SDB). This prospective study investigated the prevalence, clinical characteristics, and predictors of SDB in hospitalized HF patients. Methods Sleep studies were performed on hospitalized HF patients from January 2015 to February 2019.
Boping Huang, Yan Huang, Mei Zhai, Qiong Zhou, Shiming Ji, Huihui Liu, Xiaofeng Zhuang, Yuhui Zhang, Jian Zhang   +8 more
wiley   +1 more source

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Clinical Relevance of Drug–Drug Interactions With Antibiotics as Listed in a National Medication Formulary: Results From Two Large Population‐Based Case‐Control Studies in Patients Aged 65–100 Years Using Linked English Primary Care and Hospital Data

Clinical Pharmacology &Therapeutics, Volume 113, Issue 2, Page 423-434, February 2023., 2023
This study evaluated drug–drug interactions (DDIs) between antibiotic and nonantibiotic drugs listed with warnings of severe outcomes in the British National Formulary based on adverse drug reaction (ADR) detectable with routine International Classification of Diseases, Tenth Revision coding.
Tjeerd Pieter van Staa, Munir Pirmohamed, Anita Sharma, Iain Buchan, Darren M. Ashcroft   +4 more
wiley   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

Angiotensin receptors: history and mysteries [PDF]

American Journal of Hypertension, 2000
Angiotensin receptors became relatively easy to study when radioactive derivatives of the peptide were synthesized for radioimmunoassays. Binding assays in vitro led to the discovery of receptors in many tissues different from those involved in the classic actions of angiotensin.
openaire   +3 more sources