Results 221 to 230 of about 2,698 (247)

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Combined Angiotensin Inhibition for CKD: The Truth Is Rarely Pure and Never Simple. [PDF]

Am J Kidney Dis
Srivastava A, Schmidt IM, Palsson R.
europepmc   +1 more source

Role of the RAAS in mediating the pathophysiology of COVID-19. [PDF]

Pharmacol Rep
Jasiczek J, Doroszko A, Trocha T, Trocha M.   +3 more
europepmc   +1 more source

Structural basis of divergent substrate recognition and inhibition of human neurolysin. [PDF]

Sci Rep
Shi K, Bagchi S, Bickel J, Esfahani SH, Yin L, Cheng T, Karamyan VT, Aihara H.   +7 more
europepmc   +1 more source

Outcomes of renin-angiotensin inhibitors following transcatheter aortic valve implantation. [PDF]

Clin Cardiol
Hosseinpour A, Gupta R.
europepmc   +1 more source

Physiological and Molecular Implications of Angiotensinergic Signaling in the Brainstem.

Endocrinology
Ghobrial M, Gomez RA, Grobe JL, Sigmund CD, Nakagawa P.   +4 more
europepmc   +1 more source

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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

Circulation Research, 2020
Anthony J Turner, Anissa Viveiros, Mohan K Raizada   +2 more
exaly  

FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1–7) Axis in Mice

Cell Metabolism, 2018
Haishan Tian, Fan Wu, Aimin Xu
exaly  

Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2

Circulation, 2005
Mark C Chappell, Carlos M Ferrario, David B Averill   +2 more
exaly