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Angs (Angiotensins) of the Alternative Renin-Angiotensin System Predict Outcome in Patients With Heart Failure and Preserved Ejection Fraction

Hypertension, 2019
The renin-angiotensin system plays an important role in the development and progression of heart failure (HF). In addition to the classical renin-angiotensin pathway, an alternative pathway produces Angs (angiotensins), which counteract the negative ...
Christina Binder   +2 more
exaly   +2 more sources

Peripheral levels of angiotensins are associated with depressive symptoms in Parkinson's disease

Journal of the Neurological Sciences, 2016
Natalia Pessoa Rocha   +2 more
exaly   +2 more sources

ANGIOTENSIN HYPERTENSION

Clinical and Experimental Pharmacology and Physiology, 1998
SUMMARY1. One of the most important issues in the field of hypertension research centres on the therapeutic use of inhibitors of the renin‐angiotensin system (RAS). Inhibitors of the RAS have potent anti‐hypertensive effects, even in experimental models of hypertension and in human essential hypertension, where the activity of the peripheral RAS is low
E H, Blaine   +5 more
openaire   +2 more sources

Role of aminopeptidase activity in the regulation of the pressor activity of circulating angiotensins.

Journal of Pharmacology and Experimental Therapeutics, 1990
Aminopeptidase A (AmA; EC 3.4.11.7) can convert angiotensin II (AII) to angiotensin III (AIII), and aminopeptidase M (AmM; EC 3.4.11.2) has been shown to degrade AIII. The present study investigated angiotensin metabolism by AmA and AmM activities in rat
Saleem Ahmad, Patrick E. Ward
semanticscholar   +1 more source

Angiotensins in Alzheimer's disease – friend or foe?

Trends in Neurosciences, 2009
Patrick G Kehoe, Scott Miners, Seth Love
exaly   +2 more sources

Human Leukocytes Contain Angiotensin I, Angiotensin II and Angiotensin Metabolites

International Archives of Allergy and Immunology, 1994
Angiotensin I (ANG I) and angiotensin II (ANG II) were measured radioimmunologically in human leukocytes extracted with a mixture of acetone, 1N HCl and water (40:1:10 vol). The analytical recoveries of 125I-ANG I and 125I-ANG II, which were added prior to extraction, were 92.00 +/- 3.10 and 99.19 +/- 0.91% (mean +/- SEM; n = 12).
K, Hermann, J, Ring
openaire   +2 more sources

Is the adrenal angiotensin receptor angiotensin II — or angiotensin III like?

Acta Endocrinologica, 1983
Abstract. In order to determine whether the adrenal receptor is primarily directed at angiotensin II (All) or angiotensin III (AIII) the following in vitro experiments were performed examining aldosterone responsiveness in isolated glomerulosa cells.
L M, Braley   +3 more
openaire   +2 more sources

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