Results 101 to 110 of about 4,093 (216)

Inclisiran and siRNA-Based Lipid Lowering: A New Frontier Including ANGPTL3 Inhibitors and Apo C III Inhibitors [PDF]

Ramya Pechetty, Ping‐Fan Rao, Tripti Deb, Chandana Shekar, K. Deepthi   +4 more
openalex   +1 more source

ANGPTL3 is involved in kidney injury in high-fat diet-fed mice by suppressing ACTN4 expression [PDF]

, 2022
Guanyu Li, Di Lu, Jingzhi Wang, Shuling Yue, Mei Tan, Ming Liu, Xia Gao   +6 more
openalex   +1 more source

ANGPTL3

Journal of the American College of Cardiology, 2017
openaire   +1 more source

Inhibition of Angiopoietin-Like 3 (ANGPTL3) Reduces Adipose Tissue Insulin Resistance in Patients With Familial Partial Lipodystrophy [PDF]

, 2021
Maria Cristina Foss‐Freitas, Barış Akıncı, Adam Neidert, Rita Hench, Elif A Oral   +4 more
openalex   +1 more source

ANGPTL3 Downregulation Increases Intracellular Lipids by Reducing Energy Utilization [PDF]

Grazia Pennisi, Samantha Maurotti, Ester Ciociola, Oveis Jamialahmadi, Giorgio Bertolazzi, Angela Mirarchi, Per‐Olof Bergh, Francesca Scionti, Rosellina Margherita Mancina, Rocco Spagnuolo, Claudio Tripodo, Jan Borén, Salvatore Petta, Stefano Romeo   +13 more
openalex   +1 more source

Lipid nanoparticles incorporating a GalNAc ligand enable in vivo liver ANGPTL3 editing in wild-type and somatic LDLR knockout non-human primates [PDF]

, 2021
Lisa N. Kasiewicz, Souvik Biswas, Aaron Beach, Huilan Ren, Chaitali Dutta, Anne Marie Mazzola, Ellen Rohde, Alexandra C. Chadwick, Christopher H.K. Cheng, Kiran Musunuru, Sekar Kathiresan, Padma Malyala, Kallanthottathil G. Rajeev, Andrew M. Bellinger   +13 more
openalex   +1 more source

ANGPTL3/8: one target, multiple lipid disorders

Trends in Molecular Medicine
The angiopoietin-like protein (ANGPTL)3/8 complex regulates triglyceride partitioning, and its selective blockade lowers triglycerides while raising HDL-cholesterol (HDL-C). Clinical and genetic evidence support ANGPTL3/8 antagonism as a precision therapy for mixed dyslipidemia, monogenic hypertriglyceridemia (CREBH or APOA5 deficiency), and diabetic ...
openaire   +3 more sources

ANGPTL3 binds to PCSK9 to coordinately regulate intracellular lipid homeostasis

Simone Bini, Valeria Pecce, Alessandra Pinzon Grimaldos, Alessia Di Costanzo, Ilenia Minicocci, Stella Covino, Daniele Tramontano, Silvia Piconese, Laura D’Erasmo, Marcello Arca   +9 more
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Data from ANGPTL3 in the Peripheral Circulation Is Associated with Resistance to Anti-PD1 Therapy in Advanced Gastric Cancer

Chie Kudo-Saito, Hirokazu Shoji, Kengo Nagashima, H. Imazeki, Kai Tsugaru, Naoki Takahashi, Takeshi Kawakami, Yusuke Amanuma, Takeru Wakatsuki, Naohiro Okano, Yukiya Narita, Yoshiyuki Yamamoto, Rika Kizawa, Kei Muro, Narikazu Boku   +14 more
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Association of ANGPTL3 polymorphisms with high‐density lipoprotein cholesterol uptake capacity in patients with cardiovascular disease

, 2021
Malihe Aghasizadeh, Mina Nosrati, Maryam Saberi‐Karimian, Hamideh Safarian, Parisa Assadian, Ensieh Akbarpour, Amirhosein Sahebkar, Amir Avan, Gordon A. Ferns, Toba Kazemi, Ebrahim Miri‐Moghaddam, Majid Ghayour‐Mobarhan   +11 more
openalex   +1 more source