Results 91 to 100 of about 4,091 (198)

New Insights into the Genetic Association of Lipids and Lipid‐Modifying Target Genes with Pancreatitis

MedComm, Volume 6, Issue 12, December 2025.
Linbo Yao, Xinmin Yang, Robert Sutton, Qing Xia, Wei Huang   +4 more
wiley   +1 more source

The iPSC Awakens ANGPTL3 in Tangier Disease [PDF]

EBioMedicine, 2017
Man K.S. Lee, Andrew J. Murphy
openaire   +3 more sources

Investigation of ANGPTL3 expression, exon sequence and promotor methylation between Ningxiang and Changbai pigs

, 2013
Background: Angiopoietin-like protein 3 (ANGPTL3), a member of angiopoietin-like proteins, has been demonstrated to affect lipid metabolism by inhibiting the activity of lipoprotein lipase (LPL).
Liu, ZY, Kuang, GW, Zhang, DS, Chen, XJ, Pan, RT, Sun, ZL   +5 more
core   +2 more sources

Ewinakumab — inhibitor ANGPTL3 — nowy lek w terapii zaburzeń lipidowych. Przegląd literatury i badań klinicznych

, 2021
Białka podobne do angiopoetyny (ANGPTL) tworzą rodzinę kilku białek, z których ANGPTL3, 4 i 8 są zaangażowane w metabolizm lipidów. Białka te, odkryte stosunkowo niedawno, regulują dostępność triglicerydów dla serca, mięśni szkieletowych oraz białej i ...
Surma, Stanisław; Wydział Nauk Medycznych w Katowicach, Śląski Uniwersytet Medyczny w Katowicach, Medyków 18, 40-752 Katowice, Poland, Filipiak, Krzysztof J.; I Katedra i Klinika Kardiologii, Warszawski Uniwersytet Medyczny, Banacha 1a, pawilon D, 02-097 Warszawa, Poland, Romańczyk, Monika; Wydział Nauk Medycznych w Katowicach, Śląski Uniwersytet Medyczny w Katowicach, Medyków 18, 40-752 Katowice, Poland   +2 more
core  

The Correlation Between Angiopoietin-Like 3 and Metabolic Markers of Some Lipid and Glucose in Type 2 Diabetes Mellitus Patients at the First Diagnosis

Diabetes, Metabolic Syndrome and Obesity, 2022
Minh Hoang Thi,1 Chung Dang Thanh,2 Thuan Huynh Quang3 1Department of Pathophysiology, Vietnam Military Medical University (VMMU), Ha Noi City, Vietnam; 2Department of Pathology and Forensic Medicine, 103 Military Medical Hospital, Vietnam Military ...
Hoang Thi M, Dang Thanh C, Huynh Quang T
doaj  

ANGPTL3 facilitates lipolysis through insulin-resistance development in 3T3-L1 cells.

, 2020
Detection of loss-of-function (LOF) mutations in ANGPTL3 gene in humans revealed the existence of a new lipid phenotype, called familial combined hypolipidemia (FHBL2) and characterized by markedly reduced levels of all lipoproteins.
L. Polito, A. Ghadiri, M. Arca
core  

In Silico Description of the Direct Inhibition Mechanism of Endothelial Lipase by ANGPTL3 [PDF]

Angiopoietin-like protein 3 (ANGPTL3) is a plasmatic protein that plays a crucial role in lipoprotein metabolism by inhibiting the lipoprotein lipase (LPL) and the endothelial lipase (EL) responsible for the hydrolysis of phospholipids on high-density ...
L. Palazzolo, U. Guerrini, L. Calabresi, Alice Federica Ossoli, S. Saporiti, A. F. Ossoli, T. Laurenzi, Linda Montavoci, Simona Saporiti, I. Eberini, L. Montavoci, O. Ben Mariem, Tommaso Laurenzi, Uliano Guerrini, Laura Calabresi, Ivano Eberini, Omar Ben Mariem, Luca Palazzolo   +17 more
core   +1 more source

Abstracts of the 18th SCWD Conference, 11‐13 December 2025 in Rome/Italy

JCSM Communications, Volume 9, Issue 1, January/June 2026.
wiley   +1 more source

Downregulating ANGPTL3 by miR-144-3p promoted TGF-β1-induced renal interstitial fibrosis via activating PI3K/AKT signaling pathway

Heliyon
Despite observations of decreased ANGPTL3 (angiopoietin-like protein 3) levels in tubular atrophy and renal interstitial fibrosis (RIF), its functional implications and regulatory mechanisms in RIF remain unclear.
Bin Yang, Fengxian Shen, Yi Zhu, Haolei Cai   +3 more
doaj   +1 more source

The Effect of Canagliflozin on High-Density Lipoprotein Cholesterol and Angiopoietin-Like Protein 3 in Type 2 Diabetes Mellitus

Journal of Diabetes Research
Background. Diabetes mellitus is often accompanied by dyslipidemia. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, as a novel therapeutic agent for the treatment of type 2 diabetes mellitus (T2DM), have been reported to exert effects on lipid, while ...
Simo Liu, Jing Ke, Xiaotong Feng, Zongwei Wang, Xin Wang, Longyan Yang, Dong Zhao   +6 more
doaj   +1 more source