Angiopoietin-like proteins: a comprehensive look [PDF]
Frontiers in Endocrinology, 2014 Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date eight ANGPTLs have been discovered, named ANGPLT1 to ANGPLT8.
Gaetano eSantulli
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Distinct Clinical Impact and Biological Function of Angiopoietin and Angiopoietin-like Proteins in Human Breast Cancer [PDF]
Cells, 2021 Secreted angiopoietin/angiopoietin-like (ANGPT/ANGPTL) proteins are involved in many biological processes. However, the role of these proteins in human breast cancers (BCs) remains largely unclear. Here, we conducted integrated omics analyses to evaluate
Hui Yang +5 more
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Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer [PDF]
International Journal of Molecular Sciences, 2018 Altered expression of secreted factors by tumor cells or cells of the tumor microenvironment is a key event in cancer development and progression. In the last decade, emerging evidences supported the autocrine and paracrine activity of the members of the Angiopoietin-like (ANGPTL) protein family in angiogenesis, inflammation and in the regulation of ...
Carmine Carbone +2 more
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An Integrated Computational Analysis of High-Risk SNPs in Angiopoietin-like Proteins (ANGPTL3 and ANGPTL8) Reveals Perturbed Protein Dynamics Associated with Cancer [PDF]
Molecules, 2023 Angiopoietin-like proteins (ANGPTL) constitute a family of eight proteins (1–8) which play a pivotal role in the regulation of various pathophysiological processes.
Sajid Iqbal +4 more
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Angiopoietin-like proteins inhibitors: New horizons in the treatment of atherogenic dyslipidemia and familial hypercholesterolemia [PDF]
Cardiology Journal, 2023 Angiopoietin-like proteins (ANGPTL) are involved in the regulation of numerous physiological and biochemical processes. ANGPTL3, 4 and 8, which are involved in the regulation of lipoprotein metabolism, are particularly important.
Stanisław Surma +2 more
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Angiopoietin-like Proteins in Colorectal Cancer-A Literature Review. [PDF]
Int J Mol Sci, 2021 Colorectal cancer (CRC) is one of the most common types of malignancy, with an annual incidence of about 10% of the total number of new cases. Despite well-developed screening tests, mortality from this type of cancer remains unchanged. Therefore, it is important to search for more accurate markers that are useful in the detection of colorectal cancer (
Zajkowska M, Mroczko B.
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Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy [PDF]
BiomedicinesAngiopoietins are crucial growth factors for maintaining a healthy, functional endothelium. Patients with type 2 diabetes (T2D) exhibit significant levels of angiogenic markers, particularly Angiopoietin-2, which compromises endothelial integrity and is ...
Eman Alshawaf +10 more
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Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea [PDF]
Frontiers in Endocrinology, 2018 Objective: Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health ...
Abdulmohsen Al-Terki +9 more
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Circulating angiopoietin-like proteins in metabolic-associated fatty liver disease: a systematic review and meta-analysis [PDF]
Lipids in Health and Disease, 2021 Background Angiopoietin-like proteins (ANGPTLs) are closely related to insulin resistance and lipid metabolism, and may be a key in metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) (newly named metabolic-associated fatty liver disease (MAFLD)
Yani Ke, Shan Liu, Zheyuan Zhang, Jie Hu
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Circulating Angiopoietin-like proteins in Strongyloides Stercoralis infection and reversal following treatment. [PDF]
PLoS Neglected Tropical DiseasesStrongyloides stercoralis (Ss) is a parasitic infection affecting 50-100 million people globally, with significant immune and metabolic consequences, particularly in immunocompromised individuals.
Anuradha Rajamanickam +2 more
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