Results 41 to 50 of about 5,909,528 (224)

Angiopoietin-like protein 4 and cardiovascular function in COPD [PDF]

BMJ Open Respiratory Research, 2016
Introduction The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) is frequent and might be inter-related through inflammation-related processes reflected by specific markers.
B Waschki, AM Kirsten, O Holz, T Meyer, R Lichtinghagen, KF Rabe, H Magnussen, T Welte, H Watz, S Janciauskiene   +9 more
openaire   +2 more sources

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]

, 2005
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz, Mann, K., Ghosh, M., Machleidt, W., Machleidt, Werner, Siwanowicz, I., Ghosh, Madhumita, Holak, Tad A., Holak, T. A., Holak, T., Siwanowicz, Igor, Shanker, Sreejesh, Shanker, S.   +12 more
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Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8

Journal of Lipid Research, 2021
High plasma triglyceride (TG) levels and low HDL-C levels are risk factors for atherosclerosis and cardiovascular disease. Both plasma TG and HDL-C levels are regulated in part by the circulating inhibitor, angiopoietin-like 3 (ANGPTL3). ANGPTL3 inhibits
Kelli L. Sylvers-Davie, Ashley Segura-Roman, Alicia M. Salvi, Kylie J. Schache, Brandon S.J. Davies   +4 more
doaj   +1 more source

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis.

, 2011
OBJECTIVE: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel biomarkers of morbidity and mortality in patients with severe sepsis. DESIGN: Multicenter longitudinal cohort study.
Hawkes, Michael, Michael Hawkes, Nimerta Rajwans, W. Conrad Liles, Fox-Robichaud, Alison, Lisa J. Toltl, Alison Fox-Robichaud, Patricia C. Liaw, Cook, Deborah J, Ricciuto, Daniel R, Lafferty, Erin I, Rajwans, Nimerta, Kain, Kevin C, Andrea L. Conroy, Kevin C. Kain, Conroy, Andrea L, Daniel R. Ricciuto, Deborah J. Cook, Kahnamoui, Kamyar, Erin I. Lafferty, dos Santos, Claudia C, Liaw, Patricia C, Liles, W Conrad, Kamyar Kahnamoui, Toltl, Lisa J, Claudia C. dos Santos   +25 more
core   +1 more source

Regulation of the angiopoietin-like protein 3 gene by LXR [PDF]

Journal of Lipid Research, 2003
Angiopoietins are members of the vascular endothelial growth factor family. One family member, angiopoietin-like protein 3 (Angptl3), was recently shown to be predominantly expressed in the liver and to play an important role in regulating lipid metabolism.
Rebecca Kaplan, Theresa Zhang, Melba Hernandez, Frank Xiaodong Gan, Samuel D. Wright, M.Gerard Waters, Tian-Quan Cai   +6 more
openaire   +3 more sources

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

Haematologica, 2015
Successful expansion of hematopoietic stem cells would benefit the use of hematopoietic stem cell transplants in the clinic. Several angiopoietin-like proteins, including angiopoietin-like 7, can support the activity of hematopoietic stem cells. However,
Yiren Xiao, Zhiwu Jiang, Yin Li, Wei Ye, Bei Jia, Minjie Zhang, Yan Xu, Donghai Wu, Liangxue Lai, Yaoyu Chen, Yingjun Chang, Xiaojun Huang, Hudan Liu, Guoliang Qing, Pentao Liu, Yangqiu Li, Bing Xu, Mei Zhong, Yao Yao, Duanqing Pei, Peng Li   +20 more
doaj   +1 more source

Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats

, 2003
Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) have been identified as ligands with different effector functions of the vascular assembly and maturation-mediating receptor tyrosine kinase Tie-2.
Weiss, C, Koblizek, T., Marme, D., Augustin, HG, Augustin, H. G., Fiedler, U, Krissl, T., Martiny-Baron, G., Krissl, T, Koidl, S., Martiny-Baron, G, Deutsch, U, Fiedler, U., Weiss, C., Deutsch, U., Koidl, S, Koblizek, T, Marmé, D   +17 more
core   +1 more source

Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample

Journal of Lipid Research, 2010
We have developed and validated quantitative ELISAs for human angiopoietin-like (ANGPTL)3 and 4 and correlated their serum levels with parameters of lipid and carbohydrate metabolism.
Marius R. Robciuc, Esa Tahvanainen, Matti Jauhiainen, Christian Ehnholm   +3 more
doaj   +1 more source

Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice [PDF]

Atherosclerosis, 2020
Angiopoietin-like protein 8 (ANGPTL8) is a hormone involved in regulating lipid metabolism. Patients with coronary artery disease have markedly higher plasma levels of ANGPTL8 than controls; however, the role of ANGPTL8 in atherosclerosis has not been explored.
Xiaolu Jiao, Yunyun Yang, Linyi Li, Huahui Yu, Yunxiao Yang, Juan Li, Yunhui Du, Jing Zhang, Chaowei Hu, Yanwen Qin   +9 more
openaire   +2 more sources

Angiopoietin-like proteins - their role in lipoprotein metabolism and association with atherogenic dyslipidemia [PDF]

, 2018
Scientists have been trying to find the best parameter for laboratory assessment of the risk of cardiovasculardiseases (CVD) for decades. Initially, the results of many studies indicated that the analysisof the lipid profile was sufficient to evaluate ...
Sypniewska, Grażyna, Murawska, Karolina, Szternel, Łukasz   +2 more
core   +1 more source