Results 31 to 40 of about 22,958 (190)
Angiopoietin-like proteins, ANGPTL3, ANGPTL4, and ANGPTL8, are involved in regulating plasma lipids. In vitro and animal-based studies point to LPL and endothelial lipase (EL, LIPG) as key targets of ANGPTLs.
Fredrik Landfors +2 more
doaj +1 more source
Pentraxin-3, Angiopoietin-Like Protein-3, Angiopoietin-Like Protein-4 and Angiopoietin-Like Protein-8 Levels in Morbid Obese Children [PDF]
A low-grade inflammatory state accompanies obesity and metabolic syndrome (MetS), which are risk factors for cardiovascular diseases (CVD) in children’s future lives. The aim of this study is to investigate possible associations of pentraxin 3 (PTX3), a promising new marker for CVDs, with angiopoietin-like proteins (ANGPTL) in morbid obese (MO ...
openaire +1 more source
Angiopoietin-like protein 4 and cardiovascular function in COPD [PDF]
Introduction The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) is frequent and might be inter-related through inflammation-related processes reflected by specific markers.
B Waschki +9 more
openaire +2 more sources
Evinacumab, a human monoclonal antibody against angiopoietin-like protein 3 (ANGPTL3), has recently been approved by the U.S. Food and Drug Administration as an add-on therapy for homozygous familial hypercholesterolemia (HoFH) in patients of 12 years ...
Alice Fachin +5 more
doaj +1 more source
Psoriasis, vitiligo and lichen planus (LP) are autoimmune skin diseases associated with metabolic syndrome. Angiopoietin-like 4 (ANGPTL4) is a member of angiopoietin-like proteins, which play an important role in lipid metabolism, and its serum ...
Julia Nowowiejska +8 more
doaj +1 more source
ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
Successful expansion of hematopoietic stem cells would benefit the use of hematopoietic stem cell transplants in the clinic. Several angiopoietin-like proteins, including angiopoietin-like 7, can support the activity of hematopoietic stem cells. However,
Yiren Xiao +20 more
doaj +1 more source
Regulation of the angiopoietin-like protein 3 gene by LXR [PDF]
Angiopoietins are members of the vascular endothelial growth factor family. One family member, angiopoietin-like protein 3 (Angptl3), was recently shown to be predominantly expressed in the liver and to play an important role in regulating lipid metabolism.
Rebecca Kaplan +6 more
openaire +3 more sources
Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample
We have developed and validated quantitative ELISAs for human angiopoietin-like (ANGPTL)3 and 4 and correlated their serum levels with parameters of lipid and carbohydrate metabolism.
Marius R. Robciuc +3 more
doaj +1 more source
Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice [PDF]
Angiopoietin-like protein 8 (ANGPTL8) is a hormone involved in regulating lipid metabolism. Patients with coronary artery disease have markedly higher plasma levels of ANGPTL8 than controls; however, the role of ANGPTL8 in atherosclerosis has not been explored.
Xiaolu Jiao +9 more
openaire +2 more sources
The effects of two types of interval training on the association between cardiovascular fitness and atherogenic biomarkers with blood pressure in wWomen with overweight/obesity [PDF]
Background and Purpose: Obesity, especially central body obesity, is related to cardiovascular diseases risk factors such as high blood pressure and hyperlipidemia.
Maryam Nazari +2 more
doaj +1 more source

