Results 31 to 40 of about 22,958 (190)

Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4

open access: yesJournal of Lipid Research, 2023
Angiopoietin-like proteins, ANGPTL3, ANGPTL4, and ANGPTL8, are involved in regulating plasma lipids. In vitro and animal-based studies point to LPL and endothelial lipase (EL, LIPG) as key targets of ANGPTLs.
Fredrik Landfors   +2 more
doaj   +1 more source

Pentraxin-3, Angiopoietin-Like Protein-3, Angiopoietin-Like Protein-4 and Angiopoietin-Like Protein-8 Levels in Morbid Obese Children [PDF]

open access: yesMed One, 2017
A low-grade inflammatory state accompanies obesity and metabolic syndrome (MetS), which are risk factors for cardiovascular diseases (CVD) in children’s future lives. The aim of this study is to investigate possible associations of pentraxin 3 (PTX3), a promising new marker for CVDs, with angiopoietin-like proteins (ANGPTL) in morbid obese (MO ...
openaire   +1 more source

Angiopoietin-like protein 4 and cardiovascular function in COPD [PDF]

open access: yesBMJ Open Respiratory Research, 2016
Introduction The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) is frequent and might be inter-related through inflammation-related processes reflected by specific markers.
B Waschki   +9 more
openaire   +2 more sources

Rapid Resolution of Life-Threatening Hypertriglyceridemia after Evinacumab Administration in a Pediatric HSCT Recipient: A Case Report

open access: yesPharmaceuticals, 2023
Evinacumab, a human monoclonal antibody against angiopoietin-like protein 3 (ANGPTL3), has recently been approved by the U.S. Food and Drug Administration as an add-on therapy for homozygous familial hypercholesterolemia (HoFH) in patients of 12 years ...
Alice Fachin   +5 more
doaj   +1 more source

Angiopoietin-Like 4 (ANGPTL4) in Patients with Psoriasis, Lichen Planus and Vitiligo—A Pilot Study from the Bialystok+ Polish Longitudinal University Study

open access: yesMetabolites, 2022
Psoriasis, vitiligo and lichen planus (LP) are autoimmune skin diseases associated with metabolic syndrome. Angiopoietin-like 4 (ANGPTL4) is a member of angiopoietin-like proteins, which play an important role in lipid metabolism, and its serum ...
Julia Nowowiejska   +8 more
doaj   +1 more source

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

open access: yesHaematologica, 2015
Successful expansion of hematopoietic stem cells would benefit the use of hematopoietic stem cell transplants in the clinic. Several angiopoietin-like proteins, including angiopoietin-like 7, can support the activity of hematopoietic stem cells. However,
Yiren Xiao   +20 more
doaj   +1 more source

Regulation of the angiopoietin-like protein 3 gene by LXR [PDF]

open access: yesJournal of Lipid Research, 2003
Angiopoietins are members of the vascular endothelial growth factor family. One family member, angiopoietin-like protein 3 (Angptl3), was recently shown to be predominantly expressed in the liver and to play an important role in regulating lipid metabolism.
Rebecca Kaplan   +6 more
openaire   +3 more sources

Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample

open access: yesJournal of Lipid Research, 2010
We have developed and validated quantitative ELISAs for human angiopoietin-like (ANGPTL)3 and 4 and correlated their serum levels with parameters of lipid and carbohydrate metabolism.
Marius R. Robciuc   +3 more
doaj   +1 more source

Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice [PDF]

open access: yesAtherosclerosis, 2020
Angiopoietin-like protein 8 (ANGPTL8) is a hormone involved in regulating lipid metabolism. Patients with coronary artery disease have markedly higher plasma levels of ANGPTL8 than controls; however, the role of ANGPTL8 in atherosclerosis has not been explored.
Xiaolu Jiao   +9 more
openaire   +2 more sources

The effects of two types of interval training on the association between cardiovascular fitness and atherogenic biomarkers with blood pressure in wWomen with overweight/obesity [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: Obesity, especially central body obesity, is related to cardiovascular diseases risk factors such as high blood pressure and hyperlipidemia.
Maryam Nazari   +2 more
doaj   +1 more source

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