Results 31 to 40 of about 164,168 (220)

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS [PDF]

BMC Medicine
Background Alterations in lipid metabolism are manifestations of amyotrophic lateral sclerosis (ALS) that contribute to the risk and rate of progression.
Sruthi Sankari Krishnamurthy, Adriana Zardini Buzatto, Caley Campkin, Hans-Peter Müller, Diana Wiesner, Jochen Weishaupt, Veronika Klose, Maximilian Wiesenfarth, Zeynep Elmas, Christine Herrmann, Özlem Parlak, Kornelia Günther, Rami Saad, Ulrike Weiland, Luc Dupuis, Albert Ludolph, Liang Li, Jan Kassubek, Johannes Dorst, Francesco Roselli   +19 more
doaj   +2 more sources

Role of the angiopoietin-like protein family in the progression of NAFLD

Heliyon
Non-alcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic liver disease, with a range of conditions including non-alcoholic fatty liver, non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC).
Xin Su, Qinchen Xu, Zigan Li, Yidan Ren, Qinlian Jiao, Lina Wang, Yunshan Wang   +6 more
doaj   +3 more sources

Response of Angiopoietin-like Proteins 3 and 4 to Hemodialysis

The International Journal of Artificial Organs, 2014
Background/Aim Patients on chronic hemodialysis (cHD) have decreased activity of lipoprotein lipase (LPL). Angiopoietin-like proteins (ANGPTL) 3 and 4 have been shown to inactivate LPL. The aim of this study was to investigate the levels of the ANGPTLs in plasma of cHD-patients and to evaluate if cHD may alter ...
Dana, Mahmood, Elena, Makoveichuk, Solveig, Nilsson, Gunilla, Olivecrona, Bernd, Stegmayr   +4 more
openaire   +3 more sources

Relationship between Serum Angiopoietin-like Proteins 3 and 8 and Atherogenic Lipid Biomarkers in Non-Diabetic Adults Depends on Gender and Obesity [PDF]

Nutrients, 2021
Magdalena Krintus, Magdalena Kuligowska-Prusińska, Lukasz Szternel   +2 more
exaly   +2 more sources

Serum ANGPTL8 and ANGPTL3 as Predictors of Triglyceride Elevation in Adult Women

Metabolites, 2022
Angiopoietin-like proteins ANGPTL3 and ANGPTL8 have been shown to inhibit lipoprotein lipase, and thus regulate triglyceride level in the circulation.
Anna Stefanska, Katarzyna Bergmann, Magdalena Krintus, Magdalena Kuligowska-Prusinska, Karolina Murawska, Grazyna Sypniewska   +5 more
doaj   +1 more source

INFLUENCE OF RENAL DYSFUNCTION ON THE LEVEL OF SERUM ANGIOPOIETIN-LIKE PROTEINS AND ANTI-PHOSPHOLIPID ANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME

Медицинская иммунология, 2021
Rheumatoid arthritis (RA) is a frequent background for the development of renal pathology. Chronic kidney disease (CKD) is determined in more than 30% of patients with RA.
V. A. Aleksandrov, L. N. Shilova, A. V. Aleksandrov, N. V. Aleksandrova, I. A. Zborovskaya   +4 more
doaj   +1 more source

Gene knockdown of angiopoietin-like protein 3 reduces the occurrence and development of thoracic aortic aneurysms [PDF]

Jichu yixue yu linchuang, 2021
Objective To explore the role of angiopoietin-like protein 3 (ANGPTL3) in the development of thoracic aortic aneurysm (TAA) and its possible mechanism. Methods The TAA patients who underwent open surgical repair in Beijing Anzhen Hospital were selected
YU Hua-hui, JIAO Xiao-lu, YANG Yun-yun, LI Fan, SUN Qiu-ju, YU Yu, LYU Qian-wen, QIN Yan-wen
doaj  

Atypical angiopoietin-like protein that regulates ANGPTL3 [PDF]

Proceedings of the National Academy of Sciences, 2012
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3 , a gene located in an intron of DOCK7 , results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL family member,
Fabiana, Quagliarini, Yan, Wang, Julia, Kozlitina, Nick V, Grishin, Rhonda, Hyde, Eric, Boerwinkle, David M, Valenzuela, Andrew J, Murphy, Jonathan C, Cohen, Helen H, Hobbs   +9 more
openaire   +2 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease [PDF]

Archives of Medical Science, 2016
The aim of the current study was to examine the difference between patients detected with nonalcoholic fatty liver disease (NAFLD) and healthy subjects in terms of serum angiopoietin-like protein (ANGPTL) 2 and ANGPTL6 levels and to evaluate the correlation between ANGPTL2 and ANGPTL6 levels and liver enzyme levels, fasting glucose, lipid levels, and ...
Erkan, Gülbanu, Muratoğlu, Suzan, Erçin, Uğur, Bilgihan, Ayşe   +3 more
openaire   +3 more sources