Results 21 to 30 of about 22,958 (190)

Roles of angiopoietin-like proteins in regulation of stem cell activity [PDF]

Journal of Biochemistry, 2019
Abstract Various types of stem cells reside in the body and self-renew throughout an organism’s lifetime. Such self-renewal is essential for maintenance of tissue homeostasis and is co-ordinately regulated by stem cell-intrinsic signals and signals from stem cell niche. Angiopoietin is a niche-derived signalling molecule well known to
Yuichi Oike, Tsuyoshi Kadomatsu, Kadomatsu Tsuyoshi   +2 more
exaly   +3 more sources

Serum ANGPTL8 and ANGPTL3 as Predictors of Triglyceride Elevation in Adult Women

Metabolites, 2022
Angiopoietin-like proteins ANGPTL3 and ANGPTL8 have been shown to inhibit lipoprotein lipase, and thus regulate triglyceride level in the circulation.
Anna Stefanska, Katarzyna Bergmann, Magdalena Krintus, Magdalena Kuligowska-Prusinska, Karolina Murawska, Grazyna Sypniewska   +5 more
doaj   +1 more source

INFLUENCE OF RENAL DYSFUNCTION ON THE LEVEL OF SERUM ANGIOPOIETIN-LIKE PROTEINS AND ANTI-PHOSPHOLIPID ANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME

Медицинская иммунология, 2021
Rheumatoid arthritis (RA) is a frequent background for the development of renal pathology. Chronic kidney disease (CKD) is determined in more than 30% of patients with RA.
V. A. Aleksandrov, L. N. Shilova, A. V. Aleksandrov, N. V. Aleksandrova, I. A. Zborovskaya   +4 more
doaj   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Gene knockdown of angiopoietin-like protein 3 reduces the occurrence and development of thoracic aortic aneurysms [PDF]

Jichu yixue yu linchuang, 2021
Objective To explore the role of angiopoietin-like protein 3 (ANGPTL3) in the development of thoracic aortic aneurysm (TAA) and its possible mechanism. Methods The TAA patients who underwent open surgical repair in Beijing Anzhen Hospital were selected
YU Hua-hui, JIAO Xiao-lu, YANG Yun-yun, LI Fan, SUN Qiu-ju, YU Yu, LYU Qian-wen, QIN Yan-wen
doaj  

Atypical angiopoietin-like protein that regulates ANGPTL3 [PDF]

Proceedings of the National Academy of Sciences, 2012
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3 , a gene located in an intron of DOCK7 , results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG).
Fabiana, Quagliarini, Yan, Wang, Julia, Kozlitina, Nick V, Grishin, Rhonda, Hyde, Eric, Boerwinkle, David M, Valenzuela, Andrew J, Murphy, Jonathan C, Cohen, Helen H, Hobbs   +9 more
openaire   +2 more sources

Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease [PDF]

Archives of Medical Science, 2016
The aim of the current study was to examine the difference between patients detected with nonalcoholic fatty liver disease (NAFLD) and healthy subjects in terms of serum angiopoietin-like protein (ANGPTL) 2 and ANGPTL6 levels and to evaluate the correlation between ANGPTL2 and ANGPTL6 levels and liver enzyme levels, fasting glucose, lipid levels, and ...
Erkan, Gülbanu, Muratoğlu, Suzan, Erçin, Uğur, Bilgihan, Ayşe   +3 more
openaire   +3 more sources

Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension

Lipids in Health and Disease, 2018
Background Hypertension is a risk factor for both cardiovascular diseases (CVDs) and type 2 diabetes (T2D). Angiopoietin-like proteins (ANGPTLs), mainly ANGPTL3, ANGPTL4 and ANGPTL8, are associated with increased plasma lipid content due to their role in
Mohamed Abu-Farha, Preethi Cherian, Mohamed G. Qaddoumi, Irina AlKhairi, Devarajan Sriraman, Muath Alanbaei, Jehad Abubaker   +6 more
doaj   +1 more source

Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment

Lipids in Health and Disease, 2021
Background Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This study evaluated the level of ANGPTL3, 4, and 8 in the liver, brown adipose tissue (BAT),
Hossein Arefanian, Irina Al-Khairi, Nermeen Abu Khalaf, Preethi Cherian, Sina Kavalakatt, Dhanya Madhu, Aditi Mathur, Mohamed G. Qaddoumi, Fahd Al-Mulla, Jehad Abubaker, Mohamed Abu-Farha   +10 more
doaj   +1 more source

Differential regulation and properties of angiopoietin-like proteins 3 and 4

Journal of Lipid Research, 2005
Angiopoietin-like protein 3 and 4 (Angptl3 and Angptl4) are two members of the angiopoietin-like family of proteins. These two closely related proteins have been reported to similarly affect lipid metabolism through their capacity to inhibit lipoprotein ...
Hongfei Ge, Ji-Young Cha, Harini Gopal, Christopher Harp, Xinxin Yu, Joyce J. Repa, Cai Li   +6 more
doaj   +1 more source