A Brazilian glycoprotein E-negative bovine herpesvirus type 1.2a (BHV-1.2a) mutant is attenuated for cattle and induces protection against wild-type virus challenge [PDF]
The authors previously reported the construction of a glycoprotein E-deleted (gE-) mutant of bovine herpesvirus type 1.2a (BHV-1.2a). This mutant, 265gE-, was designed as a vaccinal strain for differential vaccines, allowing the distinction between ...
Esteves, P.A. +7 more
core
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J. +80 more
core +2 more sources
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J. +23 more
core +1 more source
Human herpesvirus-6A (HHV-6A) is rarer than HHV-6B in many infant populations. However, they are similarly prevalent as germline, chromosomally integrated genomes (ciHHV-6A/B).
Spyrou, MA +5 more
core +1 more source
Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]
Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David +23 more
core +1 more source
Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr +9 more
core +1 more source
Latent equine herpesvirus infections in horses [PDF]
A significant characteristic of the herpesviruses is that they form latent infections in infected hosts, and can be reactivated to again induce lytic infections by stressors.
Hamzah, Hazilawati
core
Characterising the adaptive t-cell immune response against Kaposi’s sarcoma-associated herpesvirus [PDF]
Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi’s sarcoma (KS), the most common malignancy in individuals with untreated HIV/AIDS.
Robey, R.C.
core
Development and validation of a real-time PCR assay for the detection of anguillid herpesvirus 1 [PDF]
Anguillid herpesvirus 1 (AngHV1) causes a haemorrhagic disease with increased mortality in wild and farmed European eel, Anguilla anguilla (L.) and Japanese eel Anguilla japonica, Temminck & Schlegel).
Haenen, O L M +5 more
core
Proteomic Profiling Skin Mucus of European Eel Anguilla anguilla Infected with Anguillid Herpesvirus. [PDF]
Li YY +5 more
europepmc +1 more source

