Results 51 to 60 of about 143,043 (309)
Damages for Wrongful Death in Alaska [PDF]
, 1988 I den här rapporten presenteras den forskning om ledarskap inom offentliga sektorn som bedrivs vid Linköpings universitet. Kartläggningen är indelad i fem olika teman: Chefers arbete och förutsättningar Ledarskap och lärande Genus och jämställdhet ...
Ingraham, Millard F.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A fobia e o pânico em suas relações com a angústia Phobia and panic related to anguish
Psicologia: Teoria e Pesquisa, 1999 Nesse texto, objetivou-se indicar as relações da angústia com as manifestações patológicas da fobia e do pânico, demonstrando a adequação da proposta de intervenção terapêutica, dentro de uma perspectiva psicanalítica.
Vera Lopes Besset +2 more
doaj
Selfhood and Relationality [PDF]
, 2017 Nineteenth century Christian thought about self and relationality was stamped by the reception of Kant’s groundbreaking revision to the Cartesian cogito.
Mariña, Jacqueline
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
PLoS ONE, 2011 We and others have recently demonstrated by immuno-EM and mutation analysis that two oocyte-restricted maternal effect genes, PADI6 and MATER, localize, in part, to the oocyte cytoplasmic lattices (CPLs).
Eric Morency +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
What\u27s Hecuba to Him, or He to Hecuba? [PDF]
, 1996 (Excerpt) My first attendance at this institute also marked the first of these Institutes. came to meet a musician classmate of mine. He was in a discussion with Edward Rechlin, the distinguished organist.
Harms, Paul W.F.
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source