Multicenter surveillance of antifungal susceptibility of clinical <i>Aspergillus</i> isolates to conventional and novel antifungal agents in Taiwan, 2021-2023. [PDF]
Hsieh M +4 more
europepmc +1 more source
CYP51C Y319H and H349R substitutions cannot confer azole resistance in <i>Aspergillus flavus</i> NRRL 3357-5. [PDF]
Zhou YB +4 more
europepmc +1 more source
Ergosterol-depleted clinical isolates of <i>Nakaseomyces glabratus</i> can develop multi-drug resistance without severe fitness defects or attenuated virulence in an invertebrate infection model. [PDF]
Aldejohann AM +16 more
europepmc +1 more source
Beyond <i>Candida</i>: Epidemiological Insights into Rare Yeast Fungaemia in Greece from a 15-Year Hospital-Based Study and Literature Review. [PDF]
Siopi M +5 more
europepmc +1 more source
Deciphering the multidrug resistance paradigm in <i>Candida auris</i>. [PDF]
Santana DJ +3 more
europepmc +1 more source
Anidulafungin, a New Echinocandin
Anidulafungin is a new echinocandin with potent in vitro activity against Aspergillus and Candida species, including those resistant to fluconazole and amphotericin B. Results of several clinical trials indicate that anidulafungin is effective in treating oesophageal candidiasis, including azole-refractory disease.
G. Morace +3 more
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Anidulafungin: an echinocandin antifungal
Expert Opinion on Investigational Drugs, 2004Anidulafungin (LY-303366, V-echinocandin trade mark, Vicuron Pharmaceuticals, Inc.) is a new echinocandin antifungal agent with broad spectrum activity against Candida and Aspergillus spp. Anidulafungin exhibits low toxicity, concentration-dependent fungicidal activity for Candida, and a prolonged post antifungal effect (> 12h).
exaly +3 more sources
Anidulafungin is a novel antifungal agent which, like other echinocandins, inhibits beta-(1,3)-D-glucan synthase and disrupts fungal cell-wall synthesis. It has marked antifungal activity against a broad spectrum of Candida spp. and Aspergillus spp., including amphotericin B- and triazole-resistant strains.
David, Murdoch, Greg L, Plosker
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